Numerical methods for self-organized shape dynamics
Discovering the decision and communication patterns cells execute when arranging into tissues is a reverse-engineering task. In order to see what…
Parallel high-performance computing for systems biology
Performing simulations of nonlinear models in 3D geometries, training deep neural nets over 3D data, and visualizing terabyte-size images in…
Biology
In close collaboration with experimental groups, we use this mechanical, physical understanding to understand how these emergent mechanical properties affect and constrain tissue…
Physics
We want to understand how the mechanical properties of individual cells emerge from those of their constituents, and in turn give rise to mechanical properties at the level of the tissues…
Biophysical Models of RNA secondary structure prediction
Most of the many computational methods that have been developed for the prediction of RNA secondary structure and the prediction of the…
Turing's Diffusive Threshold in Random Reaction-Diffusion Systems
Turing instabilities of reaction-diffusion systems can only arise if the diffusivities of the chemical species are sufficiently…
Stabilisation of Microbial Communities by Responsive Phenotypic Switching
Clonal microbes can switch between different phenotypes and recent theoretical work has shown that stochastic switching…