Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

We do pioneering basic research. 500 curiosity-driven scientists from over 50 countries ask: How do cells form tissues? Our research programs span multiple scales of magnitude, from molecular assemblies to organelles, cells, tissues, organs, and organisms.

Cell Biology

The MPI-CBG was founded with the goal of bridging scales and bringing together cell and developmental biology. For this reason, we focused heavily on studying cell biological phenomena utilizing different model systems. We can only understand how cells form tissues, our fundamental question, through a deep knowledge of cell biology.
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Physics of Life

In order to understand the organization of life into molecules, cells, and tissues the MPI-CBG, as part of a collaboration, is bringing physics and biology together to solve biological questions. This interdisciplinary effort merges fundamental physics, theory, and experiment together to truly explore how cells form tissues, the basic research question of the institute.
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Stem Cells and Organoids

Stem cells and organoids, as a model system, allows us to push forward our research into how cells form tissues. Studying tissues using organoids and the reconstitution of complex biochemical systems allow the creation of a framework of cell and tissue organization. With organoids, human tissue biology has become accessible for study in a way that was not possible before.
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Latest News

Protein dominoes

Study reveals that transcription, a basic process in gene expression, is happening in sequentially assembled specialized areas in the cell nucleus.

Biochemical Analytics Prize 2022 awarded

Prize of the German Society for Clinical Chemistry and Laboratory Medicine e. V. (DGKL) for Kai Simons, Andrej Shevchenko and Andreas Greinacher.

Making communities of microbes stable

The switching of microbes between different subgroups in response to competition can stabilise ecological communities.

Physical Biology of the Cell

DRESDEN-concept Summer School Bootcamp for Physical Biology with Rob Phillips in Dresden.

2023 Breakthrough Prize in Life Sciences for Anthony Hyman and Clifford Brangwynne

World’s largest science prize for discovering a new mechanism of cellular organization.

German Stem Cell Network awards the GSCN 2022 Hilde Mangold Award to Meritxell Huch

The 2022 Awards of the German Stem Cell Network recognize outstanding stem cell researchers.

3Rs Prize of the International Society for Transgenic Technologies for Ronald Naumann

The head of the MPI-CBG transgenic core facility receives the award for a method to reduce the number of experimental animals.

An unstable, flake-like network in the making

Dresden research team finds that the cell cortex, a fine network of filaments below the cell membrane, is activated in a controlled way by thousands…

Modern humans generate more brain neurons than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to…