30 Years Max Planck Institutes Saxony

19.9.2023 | 19:00 Uhr   Alte Börse, Naschmarkt 2, 04109 Leipzig  Leipziger Gespräch zur Mathematik mit Prof. Dr. Dr. h.c. mult. Jürgen Kurths, Potsdam-Institut für…

Research Focus - Selected Publications

Selected Publications Tan, T.H., Amiri, A., Seijo-Barandiarán, I., Staddon, M.F., Materne, A., Tomas, S., Duclut, C., Popović, M.,…

30 Years Max Planck Institutes Saxony

11.9.2023 | 19:00 – 20:00 Uhr  Kleines Haus des Staatsschauspiel Dresden, Glacisstraße 28, 01099 Dresden   Wissenschaft im Theater – Eine Vortragsreihe des Max-Planck-Instituts für…

30 Years Max Planck Institutes Saxony

5.9. – 25.9.2023 | Montag – Samstag | 10:00 – 19:00 Uhr Kulturpalast Dresden, Schloßstr. 2, 01067 Dresden Ausstellung: Pioniere des Wissens. Die Nobelpreisträger*innen der…

Publications - Artificial three-dimensional niches deconstruct pancreas development in vitro

Artificial three-dimensional niches deconstruct pancreas development in vitro We developed the first pancreas organoid model, starting from embryonic mouse pancreas progenitors. We showed that cell…

Publications

Using genetic lineage tracing, we discovered that the potential of individual pancreatic cells during development is heterogeneous at a given time point of development. We further showed the clonal…

Publications - A 3D system to model human pancreas development and its reference single cell transcriptome atlas reveal signaling pathways required for progenitor expansion

A 3D system to model human pancreas development and its reference single cell transcriptome atlas reveal signaling pathways required for progenitor expansion We established an organoid model of…

Publications - Deconstructing the principles of ductal network formation in the pancreas

Deconstructing the principles of ductal network formation in the pancreas We digitized the network of ducts of the pancreas and analysed its structure. Our results showed that its network properties…

Projects - Architectural cues controlling cell differentiation

Architectural cues controlling cell differentiation We investigate how architectural cues deployed along ducts control the differentiation of endocrine cells, notably the links between planar cell…

Projects - Pancreas organoids to model human disease

Pancreas organoids to model human disease We use human organoids to study how genes expressed during development predispose the fetus to subsequent development of cysts and diabetes.

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