19.9.2023 | 19:00 Uhr
Alte Börse, Naschmarkt 2, 04109 Leipzig
Leipziger Gespräch zur Mathematik mit Prof. Dr. Dr. h.c. mult. Jürgen Kurths, Potsdam-Institut für…
Selected Publications
Tan, T.H., Amiri, A., Seijo-Barandiarán, I., Staddon, M.F., Materne, A., Tomas, S., Duclut, C., Popović, M.,…
11.9.2023 | 19:00 – 20:00 Uhr
Kleines Haus des Staatsschauspiel Dresden, Glacisstraße 28, 01099 Dresden
Wissenschaft im Theater – Eine Vortragsreihe des Max-Planck-Instituts für…
5.9. – 25.9.2023 | Montag – Samstag | 10:00 – 19:00 Uhr
Kulturpalast Dresden, Schloßstr. 2, 01067 Dresden
Ausstellung: Pioniere des Wissens. Die Nobelpreisträger*innen der…
Artificial three-dimensional niches deconstruct pancreas development in vitro
We developed the first pancreas organoid model, starting from embryonic mouse pancreas progenitors. We showed that cell…
Using genetic lineage tracing, we discovered that the potential of individual pancreatic cells during development is heterogeneous at a given time point of development. We further showed the clonal…
A 3D system to model human pancreas development and its reference single cell transcriptome atlas reveal signaling pathways required for progenitor expansion
We established an organoid model of…
Deconstructing the principles of ductal network formation in the pancreas
We digitized the network of ducts of the pancreas and analysed its structure. Our results showed that its network properties…
Architectural cues controlling cell differentiation
We investigate how architectural cues deployed along ducts control the differentiation of endocrine cells, notably the links between planar cell…
Pancreas organoids to model human disease
We use human organoids to study how genes expressed during development predispose the fetus to subsequent development of cysts and diabetes.