Tensor clustering with algebraic constraints gives interpretable groups of crosstalk mechanisms in breast cancer
We introduce a tensor-based clustering method to extract sparse, low-dimensional…
Geometric anomaly detection in data
The quest for low-dimensional models which approximate high-dimensional data is pervasive across the physical, natural, and social sciences. The dominant paradigm…
Topological approximate Bayesian computation for parameter inference of an angiogenesis model
Inferring the parameters of models describing biological systems is an important problem in the reverse…
Algebra, Geometry and Topology of ERK Kinetics
The MEK/ERK signalling pathway is involved in cell division, cell specialisation, survival and cell death. Here we study a polynomial dynamical system…
Multiscale topology classifies cells in subcellular spatial transcriptomics
Spatial transcriptomics measures in situ gene expression at millions of locations within a tissue1, hitherto with some…
2022
Lewis Marsh, Felix Y. Zhou, Xiao Qin, Xin Lu, Helen M. Byrne, Heather A. Harrington Detecting Temporal shape changes with the Euler Characteristic Transform arXiv preprint arXiv:2212.10883 …
News
Off to the Christmas markets
Sandra and her gang went to the famous Dresden Christmas markets! Spending some quality time outside of the lab sounds great, and walking around different Christmas…
News - First lab retreat
First lab retreat
Our newly started Scharaw Lab spent its first retreat together with the amazing Grapin-Botton Lab!
What a retreat! We discussed our research and brainstormed new ideas about it,…
David Grommisch
Postdoc (since 2024) PhD (Medical Science, Karolinska Institutet, Sweden - Group of Dr. Maria Genander) M.Sc. (Biomedicine, Karolinska Institutet, Sweden) B.Sc. (Molecular…