Vanquish Neo - OT Astral LC-MS/MS setup (Thermo Fisher Scientific)
Mass range: m/z 50 - 6000(Astral analizer)/m/z 40 - 8000(Orbitrap analyzer)
Resolution: 80,000 @m/z 524; 120,000 in Zoom mode (Astral analyzer)/480,000 @m/z 200 (Orbitrap analyzer)
Sensitivity: 200 copies/cell
Mode: LC
Application: Low input and in-depth proteomics
Q Exactive HF (Thermo Fisher Scientific)
Mass range: m/z 50 - 6000
Resolution: 240,000 @ m/z 200
Sensitivity: 30-500 fg Buspirone on column
Mode: LC/Direct infusion
Application: Proteomics/Lipidomics/Intact proteins
Q Exactive HF Biopharma (Thermo Fisher Scientific)
Mass range: m/z 50 - 6000, high mass range option (HMR, biopharma)
Resolution: 240,000 @ m/z 200; 500,000 @ m/z 200
Sensitivity: 30-500 fg Buspirone on column
Mode: LC/Direct infusion
Application: Proteomics/Lipidomics
Q Exactive Calssic (Thermo Fisher Scientific)
Mass range: m/z 50 - 6000
Resolution: 140,000 @ m/z 200
Sensitivity: 50-500 fg Buspirone on column
Mode: LC/Direct infusion
Application: Lipidomics/Small molecules
nanoLC (Thermo Fisher Scientific)
Dionex Ultimate 3000, RSLCnano System, UHPLC (x2)
Dionex Ultimate 3000, HPLC
FTMS Booster X2 (Spectroswiss)
Hardware tools to access the unreduced data in FTMS
Triversa NanoMate® integrated ion source platform (x4), Advion Interchim Scientific
Mascot (Matrix Science, licensed)
Scaffold (Proteome Software, licensed)
Proteome Discoverer™ (Thermo Fisher Scientific, licensed)
Spectronaut® (Biognosys, licensed)
FragPipe https://fragpipe.nesvilab.org/
DiaNN https://github.com/vdemichev/DiaNN
SkyLine https://skyline.ms/home/project-begin.view
LipidExplorer https://apps.lifs-tools.org/lipidxplorer/
PeakStrainer https://git.mpi-cbg.de/labShevchenko/PeakStrainer/-/wikis/About
GlobeQuant https://github.com/bharathkumar91/GlobeQuant/releases