Mass spectrometers

Vanquish Neo - OT Astral LC-MS/MS setup (Thermo Fisher Scientific) 
Mass range:                                                                                                                  m/z 50 - 6000(Astral analizer)/m/z 40 - 8000(Orbitrap analyzer)
Resolution:                                                                                                                   80,000 @m/z 524; 120,000 in Zoom mode (Astral analyzer)/480,000 @m/z 200 (Orbitrap analyzer)
Sensitivity: 200 copies/cell
Mode: LC
Application: Low input and in-depth proteomics

Q Exactive HF (Thermo Fisher Scientific)
Mass range: m/z 50 - 6000
Resolution: 240,000 @ m/z 200
Sensitivity: 30-500 fg Buspirone on column
Mode: LC/Direct infusion
Application: Proteomics/Lipidomics/Intact proteins

Q Exactive HF Biopharma (Thermo Fisher Scientific)
Mass range: m/z 50 - 6000, high mass range option (HMR, biopharma)
Resolution: 240,000 @ m/z 200; 500,000 @ m/z 200
Sensitivity: 30-500 fg Buspirone on column
Mode: LC/Direct infusion
Application: Proteomics/Lipidomics

Q Exactive Calssic (Thermo Fisher Scientific)
Mass range: m/z 50 - 6000
Resolution: 140,000 @ m/z 200
Sensitivity: 50-500 fg Buspirone on column
Mode: LC/Direct infusion
Application: Lipidomics/Small molecules

Liquid chromatography

nanoLC (Thermo Fisher Scientific)
Dionex Ultimate 3000, RSLCnano System, UHPLC (x2)
Dionex Ultimate 3000, HPLC

Other

FTMS Booster X2 (Spectroswiss) 

Hardware tools to access the unreduced data in FTMS

Triversa NanoMate® integrated ion source platform (x4), Advion Interchim Scientific

Available MS-Data Processing Software

Mascot (Matrix Science, licensed)

Scaffold (Proteome Software, licensed)

Proteome Discoverer™ (Thermo Fisher Scientific, licensed)

Spectronaut® (Biognosys, licensed)

 

FragPipe https://fragpipe.nesvilab.org/

DiaNN https://github.com/vdemichev/DiaNN

SkyLine https://skyline.ms/home/project-begin.view

LipidExplorer https://apps.lifs-tools.org/lipidxplorer/

PeakStrainer https://git.mpi-cbg.de/labShevchenko/PeakStrainer/-/wikis/About

GlobeQuant  https://github.com/bharathkumar91/GlobeQuant/releases