Research areas
1. Role of compartmentalisation in tuning and regulating biochemistry
A key property of the cell is, it’s ability to compartmentalize chemical reactions. This allows the cell to…
2. Dynamic systems
In nature, an out of equilibrium state is maintained by taking energy from the environment and exploiting biochemical network complexity. As minimal synthetic cells lack this…
3. Communicating networks to regulate robustness
Biological tissues are inherently variable in their cellular compositions. In light of this variability, cells and tissues must co-ordinate their…
Methodologies:
Artificial cell synthesis Fabrication of synthetic cellular chassis Cell free expression systems Analytical methodss (spectroscopy, mass spectrometry, DLS, HPLC, NMR)…
Dynamic Protocellular systems
Biology is well equipped in exploiting a large number of out of equilibrium processes to support life. A complete understanding of these mechanisms is still in its…
Phenotypic Mutations
Transcriptional and translational errors generate diverse sequences, most dysfunctional, some harboring novel functions (Romero et. al, Prot Sci. 2022).
To detect and…
We had a great pizza party night celebrating Cedric's paper publication. Well done Cedric!
Cedric Landerer, Jonas Pöhls, Agnes Toth-Petroczy Fitness effects of phenotypic mutations at…
