Research Groups

2018

Jie Wang, Jeong-Mo Choi, Alex S Holehouse, Hyun O. Lee, Xiaojie Zhang, Marcus Jahnel, Shovamayee Maharana, Regis P. Lemaitre, Andrei I. Pozniakovsky, David N. Drechsel, Ina Poser, Rohit V Pappu, Simon Alberti, Anthony Hyman
A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins.
Cell, 174 Art. No. doi: 10.1016/j.cell.2018.06.006 (2018)
---
Simon Alberti, Shambaditya Saha, Jeffrey Woodruff, Titus Franzmann, Jie Wang, Anthony Hyman
A User's Guide for Phase Separation Assays with Purified Proteins.
J Mol Biol, Art. No. doi: 10.1016/j.jmb.2018.06.038 (2018)
---
Miroslav P Ivanov, Rene Ladurner, Ina Poser, Rebecca Beveridge, Evelyn Rampler, Otto Hudecz, Maria Novatchkova, Jean-Karim Hériché, Gordana Wutz, Petra van der Lelij, Emanuel Kreidl, James R A Hutchins, Heinz Axelsson-Ekker, Jan Ellenberg, Anthony Hyman, Karl Mechtler, Jan-Michael Peters
The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.
EMBO J, Art. No. e97150 (2018)
---
Sonja Kroschwald, Matthias Munder, Shovamayee Maharana, Titus Franzmann, Doris Richter, Martine Ruer, Anthony Hyman, Simon Alberti
Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery.
Cell Rep, 23(11) 3327-3339 (2018)
---
Richard Wheeler, Anthony Hyman
Controlling compartmentalization by non-membrane-bound organelles.
Philos Trans R Soc Lond B Biol Sci, 373(1747) Art. No. 20170193 (2018)
---
Bruce Alberts, Tony Hyman, Christopher L. Pickett, Shirley Tilghman, Harold Varmus
Improving support for young biomedical scientists.
Science, 360(6390) 716-718 (2018)
---
Petra Schwille, Joachim P. Spatz, Katharina Landfester, Eberhard Bodenschatz, Stephan Herminghaus, Victor Sourjik, Tobias Erb, Philippe Bastiaens, Reinhard Lipowsky, Anthony Hyman, Peter Dabrock, Jean-Christophe Baret, Tanja Vidakovic-Koch, Peter Bieling, Rumiana Dimova, Hannes Mutschler, Tom Robinson, Dora Tang, Seraphine Wegner, Kai Sundmacher
MaxSynBio - Avenues towards creating cells from the bottom up.
Angew Chem Int Ed Engl, Art. No. doi: 10.1002/anie.201802288 (2018)
---
Shovamayee Maharana, Jie Wang, Dimitrios Papadopoulos, Doris Richter, Andrei I. Pozniakovsky, Ina Poser, Marc Bickle, Sandra Rizk, Jordina Guillén-Boixet, Titus Franzmann, Marcus Jahnel, Lara Marrone, Young-Tae Chang, Jared Sterneckert, Pavel Tomancak, Anthony Hyman, Simon Alberti
RNA buffers the phase separation behavior of prion-like RNA binding proteins.
Science, 360(6391) 918-921 (2018)
---
Edgar Boczek, Simon Alberti
One domain fits all: Using disordered regions to sequester misfolded proteins.
J Cell Biol, 217(4) 1173-1175 (2018)
---
Radoslav Aleksandrov, Anton Dotchev, Ina Poser, Dragomir Krastev, Georgi Georgiev, Greta C Panova, Yordan Babukov, Georgi Danovski, Teodora Dyankova, Lars Hubatsch, Aneliya Ivanova, Aleksandar Atemin, Marina N Nedelcheva-Veleva, Susanne Hasse, Mihail Sarov, Frank Buchholz, Anthony Hyman, Stephan W. Grill, Stoyno Stoynov
Protein Dynamics in Complex DNA Lesions.
Mol Cell, 69(6) 1046-1061 (2018)
---
Susanne Wegmann, Bahareh Eftekharzadeh, Katharina Tepper, Katarzyna M Zoltowska, Rachel E Bennett, Simon Dujardin, Pawel R Laskowski, Danny MacKenzie, Tarun Kamath, Caitlin Commins, Charles Vanderburg, Allyson D Roe, Zhanyun Fan, Amandine M Molliex, Amayra Hernandez-Vega, Daniel Muller, Anthony Hyman, Eckhard Mandelkow, J Paul Taylor, Bradley T Hyman
Tau protein liquid-liquid phase separation can initiate tau aggregation.
EMBO J, Art. No. e98049 (2018)
---
FoSheng Hsu, Stephanie Spannl, Charles Ferguson, Anthony Hyman, Robert G. Parton, Marino Zerial
Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria.
Elife, 7 Art. No. e32282 (2018)
---
Lara Marrone, Ina Poser, Ian Casci, Julia Japtok, Peter Reinhardt, Antje Janosch, Cordula Andree, Hyun-Ok Kate Lee, Claudia Moebius, Ellen Koerner, Lydia Reinhardt, Maria Elena Cicardi, Karl Hackmann, Barbara Klink, Angelo Poletti, Simon Alberti, Marc Bickle, Andreas Hermann, Udai Pandey, Anthony Hyman, Jared Sterneckert
Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Stem Cell Reports, 10(2) 375-389 (2018)
---
Jeffrey Woodruff, Anthony Hyman, Elvan Boke
Organization and Function of Non-dynamic Biomolecular Condensates.
Trends Biochem Sci, 43(2) 81-94 (2018)
---
Marcel Naumann, Arun Pal, Anand Goswami, Xenia Lojewski, Julia Japtok, Anne Vehlow, Maximilian Naujock, René Günther, Mengmeng Jin, Nancy Stanslowsky, Peter Reinhardt, Jared Sterneckert, Marie Frickenhaus, Francisco Pan-Montojo, Erik Storkebaum, Ina Poser, Axel Freischmidt, Jochen H Weishaupt, Karlheinz Holzmann, Dirk Troost, Albert C Ludolph, Tobias M Boeckers, Stefan Liebau, Susanne Petri, Nils Cordes, Anthony Hyman, Florian Wegner, Stephan W. Grill, Joachim Weis, Alexander Storch, Andreas Hermann
Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
Nat Commun, 9(1) Art. No. 335 (2018)
---
Stephen Enos, Martin Dressler, Beatriz Ferreira Gomes, Anthony Hyman, Jeffrey Woodruff
Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit.
Biol Open, 7(1) Art. No. 029777 (2018)
---
Titus Franzmann, Marcus Jahnel, Andrei I. Pozniakovsky, Julia Mahamid, Alex S Holehouse, Elisabeth Nüske, Doris Richter, Wolfgang Baumeister, Stephan W. Grill, Rohit V Pappu, Anthony A. Hyman, Simon Alberti
Phase separation of a yeast prion protein promotes cellular fitness.
Science, 359(6371) Art. No. eaao5654 (2018)

2017

Yusuke Toyoda, Cedric J Cattin, Martin P Stewart, Ina Poser, Mirko Theis, Teymuras V. Kurzchalia, Frank Buchholz, Anthony Hyman, Daniel J. Müller
Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding.
Nat Commun, 8(1) Art. No. 1266 (2017)
---
Amayra Hernández-Vega, Marcus Braun, Lara Scharrel, Marcus Jahnel, Susanne Wegmann, Bradley T Hyman, Simon Alberti, Stefan Diez, Anthony Hyman
Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase.
Cell Rep, 20(10) 2304-2312 (2017)
---
Shambaditya Saha, Anthony Hyman
RNA gets in phase.
J Cell Biol, 216(8) 2235-2237 (2017)
---
Adam Klosin, Anthony Hyman
Molecular biology: A liquid reservoir for silent chromatin.
Nature, 547(7662) 168-170 (2017)
---
Valentina Botti, François McNicoll, Michaela Steiner, Florian M Richter, Anfisa Solovyeva, Marius Wegener, Oliver D Schwich, Ina Poser, Kathi Zarnack, Ilka Wittig, Karla M. Neugebauer, Michaela Müller-McNicoll
Cellular differentiation state modulates the mRNA export activity of SR proteins.
J Cell Biol, 216(7) 1993-2009 (2017)
---
Beata E Mierzwa, Nicolas Chiaruttini, Lorena Redondo-Morata, Joachim Moser von Filseck, Julia König, Jorge Larios, Ina Poser, Thomas Müller-Reichert, Simon Scheuring, Aurélien Roux, Daniel W Gerlich
Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis.
Nat Cell Biol, 19(7) 787-798 (2017)
---
Jeffrey Woodruff, Beatriz Ferreira Gomes, Per Widlund, Julia Mahamid, Alf Honigmann, Anthony Hyman
The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin.
Cell, 169(6) 1066-1077 (2017)
---
David G Drubin, Anthony Hyman
Stem cells: the new "model organism".
Mol Biol Cell, 28(11) 1409-1411 (2017)
---
Avinash Patel, Liliana Malinovska, Shambaditya Saha, Jie Wang, Simon Alberti, Yamuna Krishnan, Anthony Hyman
ATP as a biological hydrotrope.
Science, 356(6339) 753-756 (2017)
---
Salman F Banani, Hyun-Ok Kate Lee, Anthony Hyman, Michael K Rosen
Biomolecular condensates: organizers of cellular biochemistry.
Nat Rev Mol Cell Biol, 18(5) 285-298 (2017)
---
Daniel Mateju, Titus Franzmann, Avinash Patel, Andrii Kopach, Edgar Boczek, Shovamayee Maharana, Hyun-Ok Kate Lee, Serena Carra, Anthony Hyman, Simon Alberti
An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function.
EMBO J, 36(12) 1669-1687 (2017)
---
David Zwicker, Rabea Seyboldt, Christoph A. Weber, Anthony A. Hyman, Frank Jülicher
Growth and division of active droplets provides a model for protocells
Nat Phys, 13(4) 408-413 (2017)
---
Marie Skogs, Charlotte Stadler, Rutger Schutten, Martin Hjelmare, Christian Gnann, Lars Björk, Ina Poser, Anthony Hyman, Mathias Uhlén, Emma Lundberg
Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins.
J Proteome Res, 16(1) 147-155 (2017)
---
Nina Peel, Jyoti Iyer, Anar Naik, Michael P Dougherty, Markus Decker, Kevin F O'Connell
Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication.
PLoS Genet, 13(1) Art. No. e1006543 (2017)

2016

Ilaria Visco, Carsten Hoege, Anthony Hyman, Petra Schwille
In vitro Reconstitution of a Membrane Switch Mechanism for the Polarity Protein LGL.
J Mol Biol, 428(24 Pt A) 4828-4842 (2016)
---
Sandra Scharaw, Murat Iskar, Alessandro Ori, Gaelle Boncompain, Vibor Laketa, Ina Poser, Emma Lundberg, Franck Perez, Mike Beck, Peer Bork, Rainer Pepperkok
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
J Cell Biol, 215(4) 543-558 (2016)
---
Jacques Pécréaux, Stefanie Redemann, Zahraa Alayan, Benjamin Mercat, Sylvain Pastezeur, Carlos Garzon-Coral, Anthony Hyman, Jonathon Howard
The Mitotic Spindle in the One-Cell C. elegans Embryo Is Positioned with High Precision and Stability.
Biophys J, 111(8) 1773-1784 (2016)
---
Oliver Wueseke, David Zwicker, Anne Schwager, Yao Liang Wong, Karen Oegema, Frank Jülicher, Anthony Hyman, Jeffrey Woodruff
Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation.
Biol Open, 5(10) 1431-1440 (2016)
---
Cornelia G Spruijt, Martijn S Luijsterburg, Roberta Menafra, Rik G H Lindeboom, Pascal W T C Jansen, Raghu Ram Edupuganti, Marijke P Baltissen, Wouter W Wiegant, Moritz C Voelker-Albert, Filomena Matarese, Anneloes Mensinga, Ina Poser, Harmjan R Vos, Hendrik G Stunnenberg, Haico van Attikum, Michiel Vermeulen
ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage.
Cell Rep, 17(3) 783-798 (2016)
---
Simon Alberti, Anthony Hyman
Are aberrant phase transitions a driver of cellular aging?
Bioessays, 38(10) 959-968 (2016)
---
Shambaditya Saha, Christoph A. Weber, Marco Nousch, Omar Adame-Arana, Carsten Hoege, Marco Y Hein, Erin Osborne-Nishimura, Julia Mahamid, Marcus Jahnel, Louise Jawerth, Andrei Pozniakovski, Christian R. Eckmann, Frank Jülicher, Anthony Hyman
Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism.
Cell, 166(6) 1572-1584 (2016)
---
Jochen H Weishaupt, Tony Hyman, Ivan Dikic
Common Molecular Pathways in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Trends Mol Med, 22(9) 769-783 (2016)
---
Massimo Ganassi, Daniel Mateju, Ilaria Bigi, Laura Mediani, Ina Poser, Hyun-Ok Kate Lee, Samuel J Seguin, Federica F Morelli, Jonathan Vinet, Giuseppina Leo, Orietta Pansarasa, Cristina Cereda, Angelo Poletti, Simon Alberti, Serena Carra
A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.
Mol Cell, 63(5) 796-810 (2016)
---
Elisabeth Fischer-Friedrich, Yusuke Toyoda, Cedric J Cattin, Daniel J. Müller, Anthony Hyman, Frank Jülicher
Rheology of the Active Cell Cortex in Mitosis.
Biophys J, 111(3) 589-600 (2016)
---
Elvan Boke, Martine Ruer, Martin Wühr, Margaret Coughlin, Regis P. Lemaitre, Steven Gygi, Simon Alberti, David N. Drechsel, Anthony Hyman, Timothy J. Mitchison
Amyloid-like Self-Assembly of a Cellular Compartment.
Cell, 166(3) 637-650 (2016)
---
Sara Cuylen, Claudia Blaukopf, Antonio Z Politi, Thomas Müller-Reichert, Beate Neumann, Ina Poser, Jan Ellenberg, Anthony Hyman, Daniel W Gerlich
Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.
Nature, 535(7611) 308-312 (2016)
---
Diego Guerrera, Jimit Shah, Ekaterina Vasileva, Sophie Sluysmans, Isabelle Méan, Lionel Jond, Ina Poser, Matthias Mann, Anthony Hyman, Sandra Citi
PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.
J Biol Chem, 291(21) 11016-11029 (2016)
---
Andrés Diaz Delgadillo
Temperature drives P granule formation in Caenorhabditis elegans
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2016)
---
Radhika A Varier, Enrique Carrillo de Santa Pau, Petra van der Groep, Rik G H Lindeboom, Filomena Matarese, Anneloes Mensinga, Arne H Smits, Raghu Ram Edupuganti, Marijke P Baltissen, Pascal W T C Jansen, Natalie Ter Hoeve, Danny R van Weely, Ina Poser, Paul J van Diest, Hendrik G Stunnenberg, Michiel Vermeulen
Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.
J Biol Chem, 291(14) 7313-7324 (2016)
---
Susanne Hasse, Anthony Hyman, Mihail Sarov
TransgeneOmics - A transgenic platform for protein localization based function exploration.
Methods, 96 69-74 (2016)
---
Michaela Müller-McNicoll, Valentina Botti, Antonio Domingues, Holger Brandl, Oliver D Schwich, Michaela Steiner, Tomaz Curk, Ina Poser, Kathi Zarnack, Karla M. Neugebauer
SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export.
Genes Dev, 30(5) 553-566 (2016)
---
Ryota Uehara, Tomoko Kamasaki, Shota Hiruma, Ina Poser, Kinya Yoda, Junichiro Yajima, Daniel W Gerlich, Gohta Goshima
Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission.
Mol Biol Cell, 27(5) 812-827 (2016)
---
Julia Mahamid, Stefan Pfeffer, Miroslava Schaffer, Elizabeth Villa, Radostin Danev, Luis Kuhn Cuellar, Friedrich Förster, Anthony Hyman, Jürgen M Plitzko, Wolfgang Baumeister
Visualizing the molecular sociology at the HeLa cell nuclear periphery.
Science, 351(6276) 969-972 (2016)
---
Jan Arnold, Julia Mahamid, Vladan Lucic, Alex de Marco, Jose-Jesus Fernandez, Tim Laugks, Tobias Mayer, Anthony Hyman, Wolfgang Baumeister, Jürgen M Plitzko
Site-Specific Cryo-focused Ion Beam Sample Preparation Guided by 3D Correlative Microscopy.
Biophys J, 110(4) 860-869 (2016)
---
Ronald D Vale, Anthony Hyman
Priority of discovery in the life sciences.
Elife, 5 Art. No. e16931 (2016)
---
Xiangdong Zheng, Anand Ramani, Komal Soni, Marco Gottardo, Shuangping Zheng, Li Ming Gooi, Wenjing Li, Shan Feng, Aruljothi Mariappan, Arpit Wason, Per Widlund, Andrei I. Pozniakovsky, Ina Poser, Haiteng Deng, Guangshuo Ou, Maria Riparbelli, Callaini Giuliano, Anthony Hyman, Michael Sattler, Jay Gopalakrishnan, Haitao Li
Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length.
Nat Commun, 7 Art. No. 11874 (2016)
---
Mark Leaver, Simone Kienle, Maria L Begasse, Ralf J Sommer, Anthony Hyman
A locus in Pristionchus pacificus that is responsible for the ability to give rise to fertile offspring at higher temperatures.
Biol Open, 5(8) 1111-1117 (2016)

2015

Barbara Sorce, Carlos Escobedo, Yusuke Toyoda, Martin P Stewart, Cedric J Cattin, Richard Newton, Indranil Banerjee, Alexander Stettler, Botond Roska, Suzanne Eaton, Anthony Hyman, Andreas Hierlemann, Daniel J. Müller
Mitotic cells contract actomyosin cortex and generate pressure to round against or escape epithelial confinement.
Nat Commun, 6 Art. No. 8872 (2015)
---
Alexander Mietke, Oliver Otto, Salvatore Girardo, Philipp Rosendahl, Anna Taubenberger, Stefan Golfier, Elke Ulbricht, Sebastian Aland, Jochen Guck, Elisabeth Fischer-Friedrich
Extracting Cell Stiffness from Real-Time Deformability Cytometry: Theory and Experiment.
Biophys J, 109(10) 2023-2036 (2015)
---
Julia Mahamid, Ruud Schampers, Hans Persoon, Anthony Hyman, Wolfgang Baumeister, Jürgen M Plitzko
A focused ion beam milling and lift-out approach for site-specific preparation of frozen-hydrated lamellas from multicellular organisms.
J Struct Biol, 192(2) 262-269 (2015)
---
Marco Y Hein, Nina C Hubner, Ina Poser, Jürgen Cox, Nagarjuna Nagaraj, Yusuke Toyoda, Igor A Gak, Ina Weisswange, Jorg Mansfeld, Frank Buchholz, Anthony Hyman, Matthias Mann
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
Cell, 163(3) 712-723 (2015)
---
Avinash Patel, Hyun-Ok Kate Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus Franzmann, Andrei Pozniakovski, Ina Poser, Nicola Maghelli, Loic Royer, Martin Weigert, Eugene W Myers, Stephan W. Grill, David N. Drechsel, Anthony Hyman, Simon Alberti
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Cell, 162(5) 1066-1077 (2015)
---
Li Ding, Maciej Paszkowski-Rogacz, Maria Winzi, Debojyoti Chakraborty, Mirko Theis, Sukhdeep Singh, Giovanni Ciotta, Ina Poser, Assen Roguev, Wai Kit Chu, Chunaram Choudhary, Matthias Mann, A. Francis Stewart, Nevan J Krogan, Frank Buchholz
Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.
Cell Sys, 1(2) 141-151 (2015)
---
Simone Reber, Nathan Goehring
Intracellular Scaling Mechanisms.
Cold Spring Harb Perspect Biol, 7(12) Art. No. a019067 (2015)
---
David Zwicker, Anthony Hyman, Frank Jülicher
Suppression of Ostwald ripening in active emulsions.
Phys Rev E, 92(1) Art. No. 012317 (2015)
---
Jeffrey Woodruff, Oliver Wueseke, Valeria Viscardi, Julia Mahamid, Stacy D Ochoa, Jakob Bunkenborg, Per Widlund, Andrei I. Pozniakovsky, Esther Zanin, Shirin Bahmanyar, Andrea Zinke, Sun Hae Hong, Markus Decker, Wolfgang Baumeister, Jens S Andersen, Karen Oegema, Anthony Hyman
Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro.
Science, 348(6236) 808-812 (2015)
---
Ana Tomasovic, Nina Kurrle, Duran Sürün, Juliana Heidler, Koraljka Husnjak, Ina Poser, Frank Schnütgen, Susan Scheibe, Michael Seimetz, Peter Jaksch, Anthony Hyman, Norbert Weissmann, Harald von Melchner
Sestrin 2 Protein Regulates Platelet-derived Growth Factor Receptor β (Pdgfrβ) Expression by Modulating Proteasomal and Nrf2 Transcription Factor Functions.
J Biol Chem, 290(15) 9738-9752 (2015)
---
Oliver Wüseke
Pericentriolar material assembly in Caenorhabditis elegans
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2015)
---
Maria L Begasse, Mark Leaver, Federico Vazquez, Stephan W. Grill, Anthony Hyman
Temperature Dependence of Cell Division Timing Accounts for a Shift in the Thermal Limits of C. elegans and C. briggsae.
Cell Rep, 10(5) 647-653 (2015)
---
Subramanian Ramanathan, Jonne Helenius, Martin P Stewart, Cedric J Cattin, Anthony Hyman, Daniel J. Müller
Cdk1-dependent mitotic enrichment of cortical myosin II promotes cell rounding against confinement.
Nat Cell Biol, 17(2) 148-159 (2015)
---
Nurhan Özlü, Mohammad H Qureshi, Yusuke Toyoda, Bernhard Y Renard, Gürkan Mollaoglu, Nazlı E Özkan, Selda Bulbul, Ina Poser, Wiebke Timm, Anthony Hyman, Timothy J. Mitchison, Judith A Steen
Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis.
EMBO J, 34(2) 251-265 (2015)
---
Sonja Kroschwald, Shovamayee Maharana, Daniel Mateju, Liliana Malinovska, Elisabeth Nüske, Ina Poser, Doris Richter, Simon Alberti
Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules.
Elife, 4 Art. No. e06807 (2015)
---
Mitsuhiro Yanagida, Anthony A. Hyman, Jonathon Pines
Mitosis : a subject collection from Cold Spring Harbor Perspectives in biology
Cold Spring Harbor, N.Y, Cold Spring Harbor Laboratory Press (2015), 203 S.
---
Jeffrey Woodruff, Anthony Hyman
Method: In vitro analysis of pericentriolar material assembly.
Methods Cell Biol, 129 369-382 (2015)
---
Simone Reber, Anthony A. Hyman
Emergent Properties of the Metaphase Spindle
In: Mitosis : a subject collection form Cold Spring Harbor Perspectives in biology. (Eds.) Mitsuhiro Yanagida, Anthony A. Hyman, Jonathon Pines,Cold Spring Harbor, N.Y,Cold Spring Harbor Laboratory Press (2015),31-52

2014

Oliver Wueseke, Jakob Bunkenborg, Marco Y Hein, Andrea Zinke, Valeria Viscardi, Jeffrey Woodruff, Karen Oegema, Matthias Mann, Jens S Andersen, Anthony Hyman
The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix.
Mol Biol Cell, 25(19) 2984-2992 (2014)
---
Amr El-Labban, A Zisserman, Yusuke Toyoda, Alexander W. Bird, Anthony A. Hyman
Temporal models for mitotic phase labelling.
Med Image Anal, 18(7) 977-988 (2014)
---
Jeffrey Woodruff, Oliver Wueseke, Anthony Hyman
Pericentriolar material structure and dynamics.
Philos Trans R Soc Lond B Biol Sci, 369(1650) Art. No. 20130459 (2014)
---
Yusuke Toyoda, Cihan Erkut, Francisco Pan-Montojo, Sebastian Boland, Martin P Stewart, Daniel J. Müller, Wolfgang Wurst, Anthony Hyman, Teymuras V. Kurzchalia
Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival.
Biol Open, 3(8) 777-784 (2014)
---
David Zwicker, Markus Decker, Steffen Jaensch, Anthony Hyman, Frank Jülicher
Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles.
Proc Natl Acad Sci U.S.A., 111(26) 2636-2645 (2014)
---
Stephanie Schonegg, Anthony A. Hyman, William B. Wood
Timing and Mechanism of the Initial Cue Establishing Handed Left-Right Asymmetry in Caenorhabditis elegans Embryos
Genesis, 52(6) 572-580 (2014)
---
Michael Kuhn, Anthony Hyman, Andreas Beyer
Coiled-coil proteins facilitated the functional expansion of the centrosome.
PLoS Comput Biol, 10(6) Art. No. e1003657 (2014)
---
Anthony Hyman
Encouraging innovation.
Mol Biol Cell, 25(4) 427-428 (2014)
---
Milan Esner, Felix Meyenhofer, Michael Kuhn, Melissa Thomas, Yannis Kalaidzidis, Marc Bickle
Development of a Kinetic Assay for Late Endosome Movement.
J Biomol Screen, 19(7) 1070-1078 (2014)
---
Stefanie Redemann, Britta Weber, Marit Möller, Jean-Marc Verbavatz, Anthony Hyman, Daniel Baum, Steffen Prohaska, Thomas Müller-Reichert
The segmentation of microtubules in electron tomograms using Amira.
Methods Mol Biol, 1136 261-278 (2014)
---
Elisabeth Fischer-Friedrich, Anthony Hyman, Frank Jülicher, Daniel J. Müller, Jonne Helenius
Quantification of surface tension and internal pressure generated by single mitotic cells.
Sci Rep, 4 Art. No. 6213 (2014)
---
Anthony Hyman, Christian Weber, Frank Jülicher
Liquid-liquid phase separation in biology.
Annu Rev Cell Dev Biol, 30 39-58 (2014)
---
Xiangdong Zheng, Li Ming Gooi, Arpit Wason, Elke Gabriel, Narges Zare Mehrjardi, Qian Yang, Xingrun Zhang, Alain Debec, Marcus L Basiri, Tomer Avidor-Reiss, Andrei I. Pozniakovsky, Ina Poser, Tomo Saric, Anthony Hyman, Haitao Li, Jay Gopalakrishnan
Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis.
Proc Natl Acad Sci U.S.A., 111(3) 354-363 (2014)
---
Britta Weber, Erin M Tranfield, Johanna L Höög, Daniel Baum, Claude Antony, Tony Hyman, Jean-Marc Verbavatz, Steffen Prohaska
Automated Stitching of Microtubule Centerlines across Serial Electron Tomograms.
PLoS ONE, 9(12) Art. No. e113222 (2014)

2013

Peter Refsing Andersen, Michal Domanski, Maiken S Kristiansen, Helena Storvall, Evgenia Ntini, Celine Verheggen, Aleks Schein, Jakob Bunkenborg, Ina Poser, Marie Hallais, Rickard Sandberg, Anthony Hyman, John Lacava, Michael P Rout, Jens S Andersen, Edouard Bertrand, Torben Heick Jensen
The human cap-binding complex is functionally connected to the nuclear RNA exosome.
Nat Struct Mol Biol, 20(12) 1367-1376 (2013)
---
Jarmila Hnilicová, Samira Hozeifi, Eva Stejskalová, Eva Dušková, Ina Poser, Jana Humpolíčková, Martin Hof, David Staněk
The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.
Mol Biol Cell, 24(22) 3557-3568 (2013)
---
Simone Reber, Johannes Baumgart, Per Widlund, Andrei I. Pozniakovsky, Jonathon Howard, Anthony Hyman, Frank Jülicher
XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules
Nat Cell Biol, 15(9) 1116-1122 (2013)
---
Esther Zanin, Arshad Desai, Ina Poser, Yusuke Toyoda, Cordula Andree, Claudia Moebius, Marc Bickle, Barbara Conradt, Alisa Piekny, Karen Oegema
A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis.
Dev Cell, 26(5) 496-510 (2013)
---
Chiu Fan Lee, Clifford Brangwynne, Joebin Gharakhani, Anthony Hyman, Frank Jülicher
Spatial organization of the cell cytoplasm by position-dependent phase separation.
Phys Rev Lett, 111(8) Art. No. 088101 (2013)
---
Ryota Uehara, Yuki Tsukada, Tomoko Kamasaki, Ina Poser, Kinya Yoda, Daniel W Gerlich, Gohta Goshima
Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase.
J Cell Biol, 202(4) 623-636 (2013)
---
Marija Zanic, Per Widlund, Anthony Hyman, Jonathon Howard
Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels.
Nat Cell Biol, 15(6) 688-693 (2013)
---
Carsten Hoege, Anthony Hyman
Principles of PAR polarity in Caenorhabditis elegans embryos.
Nat Rev Mol Cell Biol, 14(5) 315-322 (2013)
---
Jessie M Jeffery, Ilya Grigoriev, Ina Poser, Armando van der Horst, Nicholas Hamilton, Nigel Waterhouse, Jonathan Bleier, V Nathan Subramaniam, Ivan V Maly, Anna Akhmanova, Kum Kum Khanna
Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment.
Cell Cycle, 12(6) 899-906 (2013)
---
Zoltan Maliga, Magno Junqueira, Yusuke Toyoda, Andreas Ettinger, Felipe Mora-Bermúdez, Robin Klemm, Andrej Vasilj, E. Guhr, Itziar Ibarlucea-Benitez, Ina Poser, Enzio Bonifacio, Wieland B. Huttner, Andrej Shevchenko, Anthony Hyman
A genomic toolkit to investigate kinesin and myosin motor function in cells.
Nat Cell Biol, 15(3) 325-334 (2013)
---
Michael C Bassik, Martin Kampmann, Robert Jan Lebbink, Shuyi Wang, Marco Y Hein, Ina Poser, Jimena Weibezahn, Max A Horlbeck, Siyuan Chen, Matthias Mann, Anthony A. Hyman, Emily M Leproust, Michael T McManus, Jonathan S. Weissman
A systematic Mammalian genetic interaction map reveals pathways underlying ricin susceptibility.
Cell, 152(4) 909-922 (2013)
---
Arne H Smits, Pascal W T C Jansen, Ina Poser, Anthony A. Hyman, Michiel Vermeulen
Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics.
Nucleic Acids Res, 41(1) Art. No. e28 (2013)
---
Julia Mahamid, Anthony Hyman, Wolfgang Baumeister
Toward Exploring the 3D Supramolecular Architecture of Centrosomes In-Situ
In: Advances in Imaging and Electron Physics ; Vol. 179. (Eds.) Peter W. Hawkes,Amsterdam, Netherlands,Academic Press (2013),147-147
---
Anthony Hyman
Funding innovative science.
Science, 339(6116) 119-119 (2013)
---
Vincent Fraisier, Amal Kasri, Stéphanie Miserey-Lenkei, Jean-Baptiste Sibarita, Deepak Nair, Adeline Mayeux, Sabine Bardin, Yusuke Toyoda, Ina Poser, Anton A Poznyakovskiy, Bruno Goud, Anthony Hyman, Ariane Dimitrov
C11ORF24 Is a Novel Type I Membrane Protein That Cycles between the Golgi Apparatus and the Plasma Membrane in Rab6-Positive Vesicles.
PLoS ONE, 8(12) Art. No. e82223 (2013)

2012

Clifford Brangwynne, Anthony A. Hyman
The Origin of Life
Nature, 491(7425) 524-525 (2012)
---
Per Widlund, Marija Podolski, Simone Reber, Joshua Alper, Marko Storch, Anthony Hyman, Jonathon Howard, David N. Drechsel
One-step purification of assembly-competent tubulin from diverse eukaryotic sources.
Mol Biol Cell, 23(22) 4393-4401 (2012)
---
Andrew Dauber, Stephen H Lafranchi, Zoltan Maliga, Julian C Lui, Jennifer E Moon, Cailin McDeed, Katrin Henke, Jonathan Zonana, Garrett A Kingman, Tune H Pers, Jeffrey Baron, Ron G Rosenfeld, Joel N Hirschhorn, Matthew P Harris, Vivian Hwa
Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein.
J Clin Endocrinol Metab, 97(11) 2140-2151 (2012)
---
Daniël Splinter, David S Razafsky, Max A Schlager, Andrea Serra-Marques, Ilya Grigoriev, Jeroen Demmers, Nanda Keijzer, Kai Jiang, Ina Poser, Anthony Hyman, Casper C Hoogenraad, Stephen J King, Anna Akhmanova
BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures.
Mol Biol Cell, 23(21) 4226-4241 (2012)
---
Kristina Uzunova, Billy T Dye, Hannelore Schutz, Rene Ladurner, Georg Petzold, Yusuke Toyoda, Marc A Jarvis, Nicholas G Brown, Ina Poser, Maria Novatchkova, Karl Mechtler, Anthony A. Hyman, Holger Stark, Brenda A Schulman, Jan-Michael Peters
APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.
Nat Struct Mol Biol, 19(11) 1116-1123 (2012)
---
Mihail Sarov, John I Murray, Kristin Schanze, Andrei Pozniakovski, Wei Niu, Karolin Angermann, Susanne Hasse, Michaela Rupprecht, Elisabeth Vinis, Matthew Tinney, Elicia A. Preston, Andrea Zinke, Susanne Enst, Tina Teichgraber, Judith Janette, Kadri Reis, Stephan Janosch, Siegfried Schloissnig, Radoslaw K Ejsmont, Cindie Slightam, Xiao Xu, Stuart K Kim, Valerie Reinke, A Francis Stewart, Michael Snyder, Robert H Waterston, Anthony A. Hyman
A Genome-Scale Resource for In Vivo Tag-Based Protein Function Exploration in C. elegans.
Cell, 150(4) 855-866 (2012)
---
Sara K Olson, Garrett Greenan, Arshad Desai, Thomas Müller-Reichert, Karen Oegema
Hierarchical assembly of the eggshell and permeability barrier in C. elegans.
J Cell Biol, 198(4) 731-748 (2012)
---
Anthony A. Hyman, Kai Simons
Cell biology. Beyond oil and water--phase transitions in cells.
Science, 337(6098) 1047-1049 (2012)
---
Claudia Wurzenberger, Michael Held, Michael A Lampson, Ina Poser, Anthony A. Hyman, Daniel W Gerlich
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores.
J Cell Biol, 198(2) 173-183 (2012)
---
Adam Frost, Marc G Elgort, Onn Brandman, Clinton Ives, Sean R. Collins, Lakshmi Miller-Vedam, Jimena Weibezahn, Marco Y Hein, Ina Poser, Matthias Mann, Anthony A. Hyman, Jonathan S. Weissman
Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions.
Cell, 149(6) 1339-1352 (2012)
---
Katharina Ross, Anna Sedello, Gabriele Putz Todd, Maciej Paszkowski-Rogacz, Alexander W. Bird, Li Ding, Tatyana Grinenko, Kira Behrens, Nina Hubner, Matthias Mann, Claudia Waskow, Carol Stocking, Frank Buchholz
Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells.
Blood, 119(18) 4152-4161 (2012)
---
Nathan Goehring, Anthony A. Hyman
Organelle growth control through limiting pools of cytoplasmic components.
Curr Biol, 22(9) 330-339 (2012)
---
Britta Weber, Garrett Greenan, Steffen Prohaska, Daniel Baum, Hans-Christian Hege, Thomas Müller-Reichert, Anthony A. Hyman, Jean-Marc Verbavatz
Automated tracing of microtubules in electron tomograms of plastic embedded samples of Caenorhabditis elegans embryos.
J Struct Biol, 178(2 SI) 129-138 (2012)
---
Nimesh Joseph, Andrea Hutterer, Ina Poser, Masanori Mishima
ARF6 GTPase protects the post-mitotic midbody from 14-3-3-mediated disintegration
EMBO J, 31(11) 2604-2614 (2012)
---
Cristina Aguirre-Portolés, Alexander W. Bird, Anthony A. Hyman, Marta Cañamero, Ignacio Pérez de Castro, Marcos Malumbres
Tpx2 controls spindle integrity, genome stability, and tumor development.
Cancer Res, 72(6) 1518-1528 (2012)
---
Li Ding, Ina Poser, Maciej Paszkowski-Rogacz, Frank Buchholz
From RNAi screens to molecular function in embryonic stem cells
Stem cell rev, 8(1) 32-42 (2012)
---
Heiko Dückert, Verena Pries, Vivek Khedkar, Sascha Menninger, Hanna Bruss, Alexander W. Bird, Zoltan Maliga, Andreas Brockmeyer, Petra Janning, Anthony A. Hyman, Stefan Grimme, Markus Schürmann, Hans Preut, Katja Hübel, Slava Ziegler, Kamal Kumar, Herbert Waldmann
Natural product-inspired cascade synthesis yields modulators of centrosome integrity.
Nat Chem Biol, 8(2) 179-184 (2012)
---
Martin P Stewart, Yusuke Toyoda, Anthony A. Hyman, Daniel J. Müller
Tracking mechanics and volume of globular cells with atomic force microscopy using a constant-height clamp.
Nat Protoc, 7(1) 143-154 (2012)
---
Alexander W. Bird, Axel Erler, Jun Fu, Jean-Karim Hériché, Marcello Maresca, Youming Zhang, Anthony A. Hyman, A Francis Stewart
High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes.
Nat Methods, 9(1) 103-109 (2012)
---
Massimilano Scolz, Per Widlund, Silvano Piazza, Debora Rosa Bublik, Simone Reber, Leticia Y Peche, Yari Ciani, Nina Hubner, Mayumi Isokane, Martin Monte, Jan Ellenberg, Anthony Hyman, Claudio Schneider, Alexander W. Bird
GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration.
PLoS ONE, 7(12) Art. No. e51259 (2012)

2011

Anthony A. Hyman
Whither systems biology.
Philos Trans R Soc Lond B Biol Sci, 366(1584) 3635-3637 (2011)
---
Simone Reber, Anthony A. Hyman
Samurai sword sets spindle size.
Cell, 147(6) 1224-1225 (2011)
---
Anthony A. Hyman, Kai Simons
Beyond HeLa cells
Nature, 480(7375) 34-34 (2011)
---
Björn Hegemann, James R A Hutchins, Otto Hudecz, Maria Novatchkova, Jonathan Rameseder, Martina M Sykora, Shang-Yun Liu, Michael Mazanek, Péter Lénárt, Jean-Karim Hériché, Ina Poser, Norbert Kraut, Anthony A. Hyman, Michael B Yaffe, Karl Mechtler, Jan-Michael Peters
Systematic phosphorylation analysis of human mitotic protein complexes.
Sci Signal, 4(198) Art. No. rs12 (2011)
---
Antigoni Elefsinioti, Ömer Sinan Saraç, Anna Hegele, Conrad Plake, Nina C Hubner, Ina Poser, Mihail Sarov, Anthony A. Hyman, Matthias Mann, Michael Schroeder, Ulrich Stelzl, Andreas Beyer
Large-scale de novo prediction of physical protein-protein association.
Mol Cell Proteomics, 10(11) Art. No. M111.010629 (2011)
---
Nathan Goehring, Philipp Khuc Trong, Justin Bois, Debanjan Chowdhury, Ernesto M Nicola, Anthony A. Hyman, Stephan W. Grill
Polarization of PAR Proteins by Advective Triggering of a Pattern-Forming System.
Science, 334(6059) 1137-1141 (2011)
---
Jason Stumpff, Yaqing Du, Chauca A English, Zoltan Maliga, Michael Wagenbach, Charles L Asbury, Linda Wordeman, Ryoma Ohi
A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A.
Mol Cell, 43(5) 764-775 (2011)
---
Markus Decker, Steffen Jaensch, Andrei I. Pozniakovsky, Andrea Zinke, Kevin F O'Connell, Wolfgang Zachariae, Eugene Myers, Anthony A. Hyman
Limiting amounts of centrosome material set centrosome size in C. elegans embryos.
Curr Biol, 21(15) 1259-1267 (2011)
---
Martin P Stewart, Yusuke Toyoda, Anthony A. Hyman, Daniel J. Müller
Force probing cell shape changes to molecular resolution.
Trends Biochem Sci, 36(8) 444-450 (2011)
---
Anthony A. Hyman, Clifford Brangwynne
Beyond stereospecificity: liquids and mesoscale organization of cytoplasm.
Dev Cell, 21(1) 14-16 (2011)
---
Nathan Goehring, Carsten Hoege, Stephan W. Grill, Anthony A. Hyman
PAR proteins diffuse freely across the anterior-posterior boundary in polarized C. elegans embryos.
J Cell Biol, 193(3) 583-594 (2011)
---
Rebecca A Green, Huey-Ling Kao, Anjon Audhya, Swathi Arur, Jonathan R Mayers, Heidi N Fridolfsson, Monty Schulman, Siegfried Schloissnig, Sherry Niessen, Kimberley Laband, Shaohe Wang, Daniel A Starr, Anthony A. Hyman, Tim Schedl, Arshad Desai, Fabio Piano, Kristin C. Gunsalus, Karen Oegema
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue.
Cell, 145(3) 470-482 (2011)
---
Lis Jakobsen, Katja Vanselow, Marie Skogs, Yusuke Toyoda, Emma Lundberg, Ina Poser, Lasse G Falkenby, Martin Bennetzen, Jens Westendorf, Erich A Nigg, Mathias Uhlen, Anthony A. Hyman, Jens S Andersen
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
EMBO J, 30(8) 1520-1535 (2011)
---
Anthony A. Hyman
Q & A Tony Hyman
Curr Biol, 21(7) 240-242 (2011)
---
Clifford Brangwynne, Timothy J. Mitchison, Anthony A. Hyman
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes.
Proc Natl Acad Sci U.S.A., 108(11) 4334-4339 (2011)
---
Julien Guizetti, Lothar Schermelleh, Jana Mäntler, Sandra Maar, Ina Poser, Heinrich Leonhardt, Thomas Müller-Reichert, Daniel W Gerlich
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments.
Science, 331(6024) 1616-1620 (2011)
---
Stefanie Redemann, Siegfried Schloissnig, Susanne Ernst, Andrei I. Pozniakovsky, Swathi Ayloo, Anthony A. Hyman, Henrik Bringmann
Codon adaptation-based control of protein expression in C. elegans.
Nat Methods, 8(3) 250-252 (2011)
---
Per Widlund, Jeffrey H. Stear, Andrei I. Pozniakovsky, Marija Zanic, Simone Reber, Gary J. Brouhard, Anthony A. Hyman, Jonathon Howard
XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region.
Proc Natl Acad Sci U.S.A., 108(7) 2741-2746 (2011)
---
Frank Schnütgen, Franziska Ehrmann, Ina Poser, Nina C Hubner, Jens Hansen, Thomas Floss, Ingrid deVries, Wolfgang Wurst, Anthony A. Hyman, Matthias Mann, Harald von Melchner
Resources for proteomics in mouse embryonic stem cells.
Nat Methods, 8(2) 103-104 (2011)
---
William M Behnke-Parks, Jeremie Vendome, Barry Honig, Zoltan Maliga, Carolyn Moores, Steven S Rosenfeld
Loop L5 acts as a conformational latch in the mitotic kinesin Eg5.
J Biol Chem, 286(7) 5242-5253 (2011)
---
Wei Niu, Zhi John Lu, Mei Zhong, Mihail Sarov, James T Murray, Cathleen M Brdlik, Judith Janette, Chao Chen, Pedro Alves, Elicia A. Preston, Cindie Slightam, Lixia Jiang, Anthony A. Hyman, Stuart K Kim, Robert H Waterston, Mark Gerstein, Michael Snyder, Valerie Reinke
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans.
Genome Res, 21(2) 245-254 (2011)
---
Martin P Stewart, Jonne H. Helenius, Yusuke Toyoda, Subramanian Ramanathan, Daniel J. Müller, Anthony A. Hyman
Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding.
Nature, 469(7329) 226-230 (2011)
---
Maria L Begasse, Anthony A. Hyman
The first cell cycle of the Caenorhabditis elegans embryo: spatial and temporal control of an asymmetric cell division.
In: Cell Cycle in Development. Results and Problems in Cell Differentiation, 53.,Berlin;Heidelberg,Springer (2011),109-133 Ch. 6
---
Christopher Gell, Claire Friel, Barbara Borgonovo, David N. Drechsel, Anthony A. Hyman, Jonathon Howard
Purification of tubulin from porcine brain.
Methods Mol Biol, 777 15-28 (2011)
---
Andreas Ettinger, Michaela Wilsch-Bräuninger, Anne-Marie Marzesco, Marc Bickle, Annett Lohmann, Zoltan Maliga, Jana Karbanová, Denis Corbeil, Anthony A. Hyman, Wieland B. Huttner
Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour.
Nat Commun, 2 Art. No. 503 (2011)

2010

Mark Gerstein, Zhi John Lu, Eric L. Van Nostrand, Chao Cheng, Bradley I. Arshinoff, Tao Liu, Kevin Y. Yip, Rebecca Robilotto, Andreas Rechtsteiner, Kohta Ikegami, Pedro Alves, Aurelien Chateigner, Marc Perry, Mitzi Morris, Raymond Auerbach, Xin Feng, Jing Leng, Anne Vielle, Wei Niu, Kahn Rhrissorrakrai, Ashish Agarwal, Roger P. Alexander, Galt Barber, Cathleen M Brdlik, Jennifer Brennan, Jeremy Jean Brouillet, Adrian Carr, Ming-Sin Cheung, Hiram Clawson, Sergio Contrino, Luke O. Dannenberg, Abby F. Dernburg, Arshad Desai, Lindsay Dick, Andréa Dosé, Jiang Du, Thea Egelhofer, Sevinc Ercan, Ghia Euskirchen, Brent Ewing, Elise A. Feingold, Reto Gassmann, Peter J. Good, Phil Green, Francois Gullier, Michelle Gutwein, Mark S. Guyer, Lukas Habegger, Ting Han, Jorja G. Henikoff, Stefan R. Henz, Angie Hinrichs, Heather Holster, Anthony A. Hyman, A. Leo Iniguez, Judith Janette, Morten Jensen, Masaomi Kato, W. James Kent, Ellen Kephart, Vishal Khivansara, Ekta Khurana, John K. Kim, Paulina Kolasinska-Zwierz, Eric C. Lai, Isabel Latorre, Amber Leahey, Suzanna E Lewis, Paul Lloyd, Lucas Lochovsky, Rebecca F. Lowdon, Yaniv Lubling, Rachel Lyne, Michael MacCoss, Sebastian D. Mackowiak, Marco Mangone, Sheldon McKay, Desirea Mecenas, Gennifer Merrihew, David M. Miller, Andrew Muroyama, John I. Murray, Siew-Loon Ooi, Hoang Pham, Taryn Phippen, Elicia A. Preston, Nikolaus Rajewski, Gunnar Rätsch, Heidi Rosenbaum, Joel Rozowksy, Kim Rutherford, Peter Ruzanov, Mihail Sarov, Rajkumar Sasidharan, Andrea Sboner, Paul Scheid, Eran Segal, Hyunjin Shin, Chong Shou, Frank J. Slack, Cindie Slightam, Richard Smith, William C. Spencer, E. O. Stinson, Scott Taing, Teruaki Takasaki, Dionne Vafeados, Ksenia Voronina, Guilin Wang, Nicole L. Washington, Christina M. Whittle, Beijing Wu, Koon-Kiu Yan, Georg Zeller, Zheng Zha, Mei Zhong, Xingliang Zhou, Julie Ahringer, Susan Strome, Kristin C. Gunsalus, Gos Micklem, X. Shirley Liu, Valerie Reinke, Stuart K Kim, LaDeana W Hillier, Steven Henikoff, Fabio Piano, Michael Snyder, Lincoln Stein, Jason D. Lieb, Robert H Waterston
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
Science, 330(6012) 1775-1787 (2010)
---
Steffen Jaensch
Time-Resolved Quantification of Centrosomes by Automated Image Analysis Suggests Limiting Component to Set Centrosome Size in C. Elegans Embryos
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2010)
---
Markus Decker
Setting centrosome size in the early caenorhabditis elegans embryo
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2010)
---
Tomoko Nishiyama, Rene Ladurner, Julia Schmitz, Emanuel Kreidl, Alexander Schleiffer, Venugopal Bhaskara, Masashige Bando, Katsuhiko Shirahige, Anthony A. Hyman, Karl Mechtler, Jan-Michael Peters
Sororin mediates sister chromatid cohesion by antagonizing Wapl.
Cell, 143(5) 737-749 (2010)
---
Nathan W. Goehring, Debanjan Chowdhury, Anthony A. Hyman, Stephan W. Grill
FRAP analysis of membrane-associated proteins: lateral diffusion and membrane-cytoplasmic exchange
Biophys J, 99(8) 2443-2452 (2010)
---
Michiel Vermeulen, H Christian Eberl, Filomena Matarese, Hendrik Marks, Sergei Denissov, Falk Butter, Kenneth K Lee, Jesper V Olsen, Anthony A. Hyman, Hendrik G Stunnenberg, Matthias Mann
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.
Cell, 142(6) 967-980 (2010)
---
Michael H A Schmitz, Michael Held, Veerle Janssens, James R A Hutchins, Otto Hudecz, Elitsa Ivanova, Jozef Goris, Laura Trinkle-Mulcahy, Angus I Lamond, Ina Poser, Anthony A. Hyman, Karl Mechtler, Jan-Michael Peters, Daniel W Gerlich
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.
Nat Cell Biol, 12(9) 886-893 (2010)
---
Cornelia G Spruijt, Stefanie J J Bartels, Arie B Brinkman, Jorrit V Tjeertes, Ina Poser, Hendrik G Stunnenberg, Michiel Vermeulen
CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.
Mol Biosyst, 6(9) 1700-1706 (2010)
---
Stefanie Redemann, Jacques Pecreaux, Nathan W. Goehring, Khaled Khairy, Ernst H K Stelzer, Anthony A. Hyman, Jonathon Howard
Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos.
PLoS ONE, 5(8) Art. No. e12301 (2010)
---
Carsten Hoege, Alexandru T. Constantinescu, Anne Schwager, Nathan W. Goehring, Prateek Kumar, Anthony A. Hyman
LGL can partition the cortex of one-cell Caenorhabditis elegans embryos into two domains.
Curr Biol, 20(14) 1296-1303 (2010)
---
Steffen Jaensch, Markus Decker, Anthony A. Hyman, Eugene Myers
Automated tracking and analysis of centrosomes in early Caenorhabditis elegans embryos
Bioinformatics, 26(12) 13-20 (2010)
---
Nina C. Hubner, Alexander W. Bird, Jürgen Cox, Bianca Splettstoesser, Peter Bandilla, Ina Poser, Anthony A. Hyman, Matthias Mann
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions.
J Cell Biol, 189(4) 739-754 (2010)
---
Sergey Lekomtsev, Julien Guizetti, Andrei I. Pozniakovsky, Daniel W Gerlich, Mark Petronczki
Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells.
J Cell Sci, 123(Pt 9) 1395-1400 (2010)
---
Christian Schenk, Henrik Bringmann, Anthony A. Hyman, Carrie R. Cowan
Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos.
Development, 137(10) 1743-1753 (2010)
---
James R A Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M Sykora, Martina Augsburg, Otto Hudecz, Bettina A Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei I. Pozniakovsky, Mikolaj Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Science, 328(5978) 593-599 (2010)
---
Nadja C Hübner, Lily Hui-Ching Wang, Manuel Kaulich, Patrick Descombes, Ina Poser, Erich A Nigg
Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs.
Chromosoma, 119(2) 149-165 (2010)
---
Beate Neumann, Thomas Walter, Jean-Karim Hériché, Jutta Bulkescher, Holger Erfle, Christian Conrad, Phill Rogers, Ina Poser, Michael Held, Urban Liebel, Cihan Cetin, Frank Sieckmann, Gregoire Pau, Rolf Kabbe, Annelie Wünsche, Venkata Satagopam, Michael H A Schmitz, Catherine Chapuis, Daniel W Gerlich, Reinhard Schneider, Roland Eils, Wolfgang Huber, Jan-Michael Peters, Anthony A. Hyman, Richard Durbin, Rainer Pepperkok, Jan Ellenberg
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.
Nature, 464(7289) 721-727 (2010)
---
Mei Zhong, Wei Niu, Zhi John Lu, Mihail Sarov, James T Murray, Judith Janette, Debasish Raha, Karyn L Sheaffer, Hugo Y K Lam, Elicia A. Preston, Cindie Slightam, LaDeana W Hillier, Trisha Brock, Ashish Agarwal, Raymond Auerbach, Anthony A. Hyman, Mark Gerstein, Susan E Mango, Stuart K Kim, Robert H Waterston, Valerie Reinke, Michael Snyder
Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response.
PLoS Genet, 6(2) Art. No. e1000848 (2010)
---
Alessia Errico, Krupa Deshmukh, Yoshimi Tanaka, Andrei I. Pozniakovsky, Tim Hunt
Identification of substrates for cyclin dependent kinases.
Adv Enzyme Regul, 50(1) 375-399 (2010)
---
Garrett Greenan, Clifford Brangwynne, Steffen Jaensch, Joebin Gharakhani, Frank Jülicher, Anthony A. Hyman
Centrosome size sets mitotic spindle length in Caenorhabditis elegans embryos.
Curr Biol, 20(4) 353-358 (2010)
---
Garrett Greenan
Setting mitotic spindle length in the early Caenorhabditis elegans embryo
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2010)

2009

Jonathon Howard, Anthony A. Hyman
Growth, fluctuation and switching at microtubule plus ends.
Nat Rev Mol Cell Biol, 10(8) 569-574 (2009)
---
Clifford Brangwynne, Christian R. Eckmann, David S Courson, Agata Rybarska, Carsten Hoege, Joebin Gharakhani, Frank Jülicher, Anthony A. Hyman
Germline P granules are liquid droplets that localize by controlled dissolution/condensation.
Science, 324(5935) 1729-1732 (2009)
---
Steffen Lawo, Mikhail Bashkurov, Michael Mullin, Mariana Gomez Ferreria, Ralf Kittler, Bianca Habermann, Andrea Tagliaferro, Ina Poser, James R A Hutchins, Björn Hegemann, Deborah Pinchev, Frank Buchholz, Jan-Michael Peters, Anthony A. Hyman, Anne-Claude Gingras, Laurence Pelletier
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.
Curr Biol, 19(10) 816-826 (2009)
---
Stefanie Redemann
The role of the acto-myosin cortex for force-generation and spindle positioning in the C. elegans embryo
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2009)
---
Marija Zanic, Jeffrey H. Stear, Jonathon Howard, Anthony A. Hyman
EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.
PLoS ONE, 4(10) Art. No. e7585 (2009)

2008

Zdenek Petrásek, Carsten Hoege, Alireza Mashaghi, Thomas Ohrt, Anthony A. Hyman, Petra Schwille
Characterization of protein dynamics in asymmetric cell division by scanning fluorescence correlation spectroscopy.
Biophys J, 95(11) 5476-5486 (2008)
---
Julien Mouysset, Alexandra Deichsel, Sandra Moser, Carsten Hoege, Anthony A. Hyman, Anton Gartner, Thorsten Hoppe
Cell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication.
Proc Natl Acad Sci U.S.A., 105(35) 12879-12884 (2008)
---
Mike Boxem, Zoltan Maliga, Niels Klitgord, Na Li, Irma Lemmens, Miyeko Mana, Lorenzo de Lichtervelde, Joram D. Mul, Diederik van de Peut, Maxime Devos, Nicolas Simonis, Muhammed A. Yildirim, Murat Cokol, Huey-Ling Kao, Anne-Sophie de Smet, Anne-Lore Schlaitz, Haidong Wang, Tong Hao, Stuart Milstein, Changyu Fan, Mike Tipsword, Kevin Drew, Matilde Galli, Kahn Rhrissorrakrai, David N. Drechsel, Daphne Koller, Frederick P. Roth, Lilia M. Iakoucheva, A. Keith Dunker, Richard Bonneau, Kristin C. Gunsalus, David E. Hill, Fabio Piano, Jan Tavernier, Sander van den Heuvel, Anthony A. Hyman, Marc Vidal
A protein domain-based interactome network for C. elegans early embryogenesis.
Cell, 134(3) 534-545 (2008)
---
Alexander W. Bird, Anthony A. Hyman
Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A.
J Cell Biol, 182(2) 289-300 (2008)
---
Ina Poser, Mihail Sarov, James R A Hutchins, Jean-Karim Hériché, Yusuke Toyoda, Andrei I. Pozniakovsky, Daniela Weigl, Anja Nitzsche, Björn Hegemann, Alexander W. Bird, Laurence Pelletier, Ralf Kittler, Sujun Hua, Ronald Naumann, Martina Augsburg, Martina M Sykora, Helmut Hofemeister, Youming Zhang, Kim Nasmyth, Kevin P White, Steffen Dietzel, Karl Mechtler, Richard Durbin, A. Francis Stewart, Jan-Michael Peters, Frank Buchholz, Anthony A. Hyman
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.
Nat Methods, 5(5) 409-415 (2008)
---
Gary J. Brouhard, Jeffrey H. Stear, Tim L. Noetzel, Jawdat Al-Bassam, Kazuhisa Kinoshita, Stephen C. Harrison, Jonathon Howard, Anthony A. Hyman
XMAP215 is a processive microtubule polymerase.
Cell, 132(1) 79-88 (2008)
---
Fei Zhu, Steffen Lawo, Alexander W. Bird, Deborah Pinchev, Alison Ralph, Constance Richter, Thomas Müller-Reichert, Ralf Kittler, Anthony A. Hyman, Laurence Pelletier
The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis.
Curr Biol, 18(2) 136-141 (2008)
---
Rebecca A. Green, Anjon Audhya, Andrei I. Pozniakovsky, Alexander Dammermann, Hayley Pemble, Joost Monen, Nathan Portier, Anthony A. Hyman, Arshad Desai, Karen Oegema
Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo
In: Fluorescent Proteins. (Eds.) Kevin F. Sullivan Methods in cell biology, 85.,Amsterdam, Netherlands,Elsevier (2008),179-218 Ch. 9
---
Victor F Lundin, Martin Srayko, Anthony A. Hyman, Michel R Leroux
Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans.
Dev Biol, 313(1) 320-334 (2008)

2007

Céline Elie-Caille, Fedor F. Severin, Jonne H. Helenius, Jonathon Howard, Daniel J. Müller, Anthony A. Hyman
Straight GDP-tubulin protofilaments form in the presence of taxol.
Curr Biol, 17(20) 1765-1770 (2007)
---
Stephanie Schonegg, Alexandru T. Constantinescu, Carsten Hoege, Anthony A. Hyman
The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos.
Proc Natl Acad Sci U.S.A., 104(38) 14976-14981 (2007)
---
Thomas J. F. Nieland, Jared T Shaw, Firoz A Jaipuri, Zoltan Maliga, Jay L Duffner, Angela N Koehler, Monty Krieger
Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.
J Lipid Res, 48(8) 1832-1845 (2007)
---
Peter C Stirling, Martin Srayko, Karam S Takhar, Andrei I. Pozniakovsky, Anthony A. Hyman, Michel R Leroux
Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression.
Mol Biol Cell, 18(6) 2336-2345 (2007)
---
Jawdat Al-Bassam, Nicholas A. Larsen, Anthony A. Hyman, Stephen C. Harrison
Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding.
Structure, 15(3) 355-362 (2007)
---
Carrie R. Cowan, Anthony A. Hyman
Acto-myosin reorganization and PAR polarity in C. elegans.
Development, 134(6) 1035-1043 (2007)
---
Alexander Zumdieck, Karsten Kruse, Henrik Bringmann, Anthony A. Hyman, Frank Jülicher
Stress generation and filament turnover during actin ring constriction.
PLoS ONE, 2(1) 696-696 (2007)
---
Jonathon Howard, Anthony A. Hyman
Microtubule polymerases and depolymerases.
Curr Opin Cell Biol, 19(1) 31-35 (2007)
---
Daisuke Mori, Yoshihisa Yano, Kazuhito Toyo-oka, Noriyuki Yoshida, Masami Yamada, Masami Muramatsu, Dongwei Zhang, Hideyuki Saya, Yoko Y Toyoshima, Kazuhisa Kinoshita, Anthony Wynshaw-Boris, Shinji Hirotsune
NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment.
Mol Cell Biol, 27(1) 352-367 (2007)
---
David A. Cisneros
Molecular assemblies observed by atomic force microscopy
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2007)
---
Amani Said
Mechanisms underlying cell sorting at the A-P compartment boundary in the Drosophila wing
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2007)
---
Henrik Bringmann, Carrie R. Cowan, Jun Kong, Anthony A. Hyman
LET-99, GOA-1/GPA-16, and GPR-1/2 are required for aster-positioned cytokinesis.
Curr Biol, 17(2) 185-191 (2007)
---
Henrik Bringmann
Experiments concerning the mechanisms of cytokinesis in Caenorhabditis elegans embryos
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2007)

2006

Carrie R. Cowan, Anthony A. Hyman
Cyclin E-Cdk2 temporally regulates centrosome assembly and establishment of polarity in Caenorhabditis elegans embryos.
Nat Cell Biol, 8(12) 1441-1447 (2006)
---
Sharsti Sandall, Fedor F. Severin, Ian X. McLeod, John R. Yates, Karen Oegema, Anthony A. Hyman, Arshad Desai
A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension.
Cell, 127(6) 1179-1191 (2006)
---
Jacques Pecreaux, Jens-Christian Röper, Karsten Kruse, Frank Jülicher, Anthony A. Hyman, Stephan W. Grill, Jonathon Howard
Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators.
Curr Biol, 16(21) 2111-2122 (2006)
---
Laurence Pelletier, Eileen T. O'Toole, Anne Schwager, Anthony A. Hyman, Thomas Müller-Reichert
Centriole assembly in Caenorhabditis elegans.
Nature, 444(7119) 619-623 (2006)
---
Mihail Sarov, Susan Schneider, Andrei I. Pozniakovsky, Assen Roguev, Susanne Ernst, Youming Zhang, Anthony A. Hyman, A. Francis Stewart
A recombineering pipeline for functional genomics applied to Caenorhabditis elegans.
Nat Methods, 3(10) 839-844 (2006)
---
Vladimir Varga, Jonne H. Helenius, Kozo Tanaka, Anthony A. Hyman, Tomoyuki U Tanaka, Jonathon Howard
Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner.
Nat Cell Biol, 8(9) 957-962 (2006)
---
Stephanie Schonegg, Anthony A. Hyman
CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos.
Development, 133(18) 3507-3516 (2006)
---
Jacob W. J. Kerssemakers, Emilia-Laura Munteanu, Liedewij Laan, Tim L. Noetzel, Marcel E Janson, Marileen Dogterom
Assembly dynamics of microtubules at molecular resolution.
Nature, 442(7103) 709-712 (2006)
---
Gaspare Benenati
Osmotic balance and establishment of polarity in the C. elegans embryo require cytochrome P450 CYP31A
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2006)
---
Jawdat Al-Bassam, Mark van Breugel, Stephen C. Harrison, Anthony A. Hyman
Stu2p binds tubulin and undergoes an open-to-closed conformational change.
J Cell Biol, 172(7) 1009-1022 (2006)
---
Cerasela Z. Dinu
Leveraging the motor protein kinesin to manipulate DNA molecules in synthetic environment
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2006)
---
Svyatoslav Sokolov, Dmitry A. Knorre, Ekaterina Smirnova, Olga V. Markova, Andrei I. Pozniakovsky, Vladimir P. Skulachev, Fedor F. Severin
Ysp2 mediates death of yeast induced by amiodarone or intracellular acidification.
Biochim Biophys Acta, 1757(9-10) 1366-1370 (2006)
---
Kazuhisa Kinoshita, Tim L. Noetzel, Isabelle Arnal, David N. Drechsel, Anthony A. Hyman
Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1.
J Muscle Res Cell Motil, 27(2) 107-114 (2006)
---
Svyatoslav Sokolov, Andrei I. Pozniakovsky, Natalia Bocharova, Dmitry A. Knorre, Fedor F. Severin
Expression of an expanded polyglutamine domain in yeast causes death with apoptotic markers.
Biochim Biophys Acta, 1757(5-6) 660-666 (2006)
---
K. Tanuj Sapra, Hüseyin Besir, Dieter Oesterhelt, Daniel J. Müller
Characterizing molecular interactions in different bacteriorhodopsin assemblies by single-molecule force spectroscopy.
J Mol Biol, 355(4) 640-650 (2006)
---
Karen Oegema, Anthony A. Hyman
Cell division.
WormBook : the online review of C. elegans biology, Jan 19 1-40 (2006)

2005

Henrik Bringmann
Cytokinesis and the spindle midzone.
Cell Cycle, 4(12) 1709-1712 (2005)
---
Stephanie Schonegg
Rho GTPase family members in establishment of polarity in C.elegans embryos
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2005)
---
Kazuhisa Kinoshita, Tim L. Noetzel, Laurence Pelletier, Karl Mechtler, David N. Drechsel, Anne Schwager, Mike Lee, Jordan W Raff, Anthony A. Hyman
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis.
J Cell Biol, 170(7) 1047-1055 (2005)
---
Teresa P. Barros, Kazuhisa Kinoshita, Anthony A. Hyman, Jordan W Raff
Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules.
J Cell Biol, 170(7) 1039-1046 (2005)
---
Kristin C. Gunsalus, Hui Ge, Aaron J Schetter, Debra S Goldberg, Jing-Dong J Han, Tong Hao, Gabriel F Berriz, Nicolas Bertin, Jerry Huang, Ling-Shiang Chuang, Ning Li, Ramamurthy Mani, Anthony A. Hyman, Birte Sönnichsen, Christophe J. Echeverri, Frederick P. Roth, Marc Vidal, Fabio Piano
Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis.
Nature, 436(7052) 861-865 (2005)
---
Martin Srayko, Aynur Kaya, Joanne Stamford, Anthony A. Hyman
Identification and characterization of factors required for microtubule growth and nucleation in the early C. elegans embryo.
Dev Cell, 9(2) 223-236 (2005)
---
Nurhan Ozlü, Martin Srayko, Kazuhisa Kinoshita, Bianca Habermann, Eileen T. O'Toole, Thomas Müller-Reichert, Natalie Schmalz, Arshad Desai, Anthony A. Hyman
An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles.
Dev Cell, 9(2) 237-248 (2005)
---
Henrik Bringmann, Anthony A. Hyman
A cytokinesis furrow is positioned by two consecutive signals.
Nature, 436(7051) 731-734 (2005)
---
Thimo Kurz, Nurhan Ozlü, Fabian Rudolf, Sean M O'Rourke, Brian Luke, Kay Hofmann, Anthony A. Hyman, Bruce Bowerman, Matthias Peter
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.
Nature, 435(7046) 1257-1261 (2005)
---
Stephan W. Grill, Anthony A. Hyman
Spindle positioning by cortical pulling forces.
Dev Cell, 8(4) 461-465 (2005)
---
Kozo Tanaka, Naomi Mukae, Hilary Dewar, Mark van Breugel, Euan K James, Alan R Prescott, Claude Antony, Tomoyuki U Tanaka
Molecular mechanisms of kinetochore capture by spindle microtubules.
Nature, 434(7036) 987-994 (2005)
---
Birte Sönnichsen, L B Koski, A Walsh, P Marschall, B Neumann, Michael Brehm, Anne-Marie Alleaume, J. Artelt, P Bettencourt, E Cassin, M Hewitson, Christian Holz, M Khan, S Lazik, Claudia Martin, Bert Nitzsche, Martine Ruer, Joanne Stamford, Maria Winzi, R Heinkel, M Röder, J Finell, H Häntsch, S J M Jones, M Jones, Fabio Piano, Kristin C. Gunsalus, Karen Oegema, Pierre Gönczy, A Coulson, Anthony A. Hyman, C J Echeverri
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans.
Nature, 434(7032) 462-469 (2005)
---
Anthony A. Hyman
Boveri revisited.
EMBO J, 24(6) 1104-1110 (2005)
---
Tim L. Noetzel, David N. Drechsel, Anthony A. Hyman, Kazuhisa Kinoshita
A comparison of the ability of XMAP215 and tau to inhibit the microtubule destabilizing activity of XKCM1.
Philos Trans R Soc Lond B Biol Sci, 360(1455) 591-594 (2005)
---
Ralf Kittler, Laurence Pelletier, Chunling Ma, Ina Poser, Steffi Fischer, Anthony A. Hyman, Frank Buchholz
RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells.
Proc Natl Acad Sci U.S.A., 102(7) 2396-2401 (2005)
---
Andrei I. Pozniakovsky, Dmitry A. Knorre, Olga V. Markova, Anthony A. Hyman, Vladimir P. Skulachev, Fedor F. Severin
Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast.
J Cell Biol, 168(2) 257-269 (2005)
---
Andriy Kovalchuk
Molecular analysis of the LTR Retrotransposon Ylt1 from the genome of dimorphic fungus yarrowia lipolytica
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2005)
---
Anthony A. Hyman, Jonathon Howard
Cell structure and dynamics
Curr Opin Cell Biol, 17 1-2 (2005)

2004

Henry Hess, Jens-Christian Röper, Stephan W. Grill, Michael R Koelle
RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans.
Cell, 119(2) 209-218 (2004)
---
Carrie R. Cowan, Anthony A. Hyman
Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos.
Nature, 431(7004) 92-96 (2004)
---
Srinath Sampath, Ryoma Ohi, Oliver Leismann, Adrian Salic, Andrei I. Pozniakovsky, Hironori Funabiki
The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.
Cell, 118(2) 187-202 (2004)
---
Laurence Pelletier, Nurhan Ozlü, Eva Hannak, Carrie R. Cowan, Bianca Habermann, Martine Ruer, Thomas Müller-Reichert, Anthony A. Hyman
The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication.
Curr Biol, 14(10) 863-873 (2004)
---
Henrik Bringmann, Georgios Skiniotis, Annina Spilker, Stefanie Kandels-Lewis, Isabelle Vernos, Thomas Surrey
A kinesin-like motor inhibits microtubule dynamic instability.
Science, 303(5663) 1519-1522 (2004)
---
Bruce T Schaar, Kazuhisa Kinoshita, Susan K McConnell
Doublecortin microtubule affinity is regulated by a balance of kinase and phosphatase activity at the leading edge of migrating neurons.
Neuron, 41(2) 203-213 (2004)
---
Carrie R. Cowan, Anthony A. Hyman
Asymmetric cell division in C. elegans: cortical polarity and spindle positioning.
Annu Rev Cell Dev Biol, 20 427-453 (2004)

2003

Sophie Quintin, Paul E Mains, Andrea Zinke, Anthony A. Hyman
The mbk-2 kinase is required for inactivation of MEI-1/katanin in the one-cell Caenorhabditis elegans embryo.
EMBO Rep, 4(12) 1175-1181 (2003)
---
Eileen T. O'Toole, Kent McDonald, Jana Mäntler, J. Richard McIntosh, Anthony A. Hyman, Thomas Müller-Reichert
Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans.
J Cell Biol, 163(3) 451-456 (2003)
---
Martin Srayko, Sophie Quintin, Anne Schwager, Anthony A. Hyman
Caenorhabditis elegans TAC-1 and ZYG-9 form a complex that is essential for long astral and spindle microtubules.
Curr Biol, 13(17) 1506-1511 (2003)
---
Mark van Breugel, David N. Drechsel, Anthony A. Hyman
Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family of microtubule-associated proteins is a plus end-binding microtubule destabilizer.
J Cell Biol, 161(2) 359-369 (2003)
---
Jonathon Howard, Anthony A. Hyman
Dynamics and mechanics of the microtubule plus end.
Nature, 422(6933) 753-758 (2003)
---
Thomas Müller-Reichert, Ingrid Sassoon, Eileen T. O'Toole, Maryse Romao, Anthony J. Ashford, Anthony A. Hyman, Claude Antony
Analysis of the distribution of the kinetochore protein Ndc10p in Saccharomyces cerevisiae using 3-D modeling of mitotic spindles.
Chromosoma, 111(7) 417-428 (2003)
---
Matthew Kirkham, Thomas Müller-Reichert, Karen Oegema, Stephan W. Grill, Anthony A. Hyman
SAS-4 is a C. elegans centriolar protein that controls centrosome size.
Cell, 112(4) 575-587 (2003)

2002

Manuel Mendoza, Anthony A. Hyman, Michael Glotzer
GTP binding induces filament assembly of a recombinant septin.
Curr Biol, 12(21) 1858-1863 (2002)
---
Susanne Kaitna, Heinke Schnabel, Ralf Schnabel, Anthony A. Hyman, Michael Glotzer
A ubiquitin C-terminal hydrolase is required to maintain osmotic balance and execute actin-dependent processes in the early C. elegans embryo.
J Cell Sci, 115(Pt 11) 2293-2302 (2002)
---
Eva Hannak, Karen Oegema, Matthew Kirkham, Pierre Gönczy, Bianca Habermann, Anthony A. Hyman
The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent.
J Cell Biol, 157(4) 591-602 (2002)

2001

Eva Hannak, Matthew Kirkham, Anthony A. Hyman, Karen Oegema
Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans.
J Cell Biol, 155(7) 1109-1116 (2001)
---
Pierre Gönczy, Jean-Michel Bellanger, Matthew Kirkham, Andrei Pozniakovski, Karine Baumer, Jennifer B. Phillips, Anthony A. Hyman
zyg-8, a gene required for spindle positioning in C. elegans, encodes a doublecortin-related kinase that promotes microtubule assembly.
Dev Cell, 1(3) 363-375 (2001)
---
Karen Oegema, Arshad Desai, Sonja Rybina, Matthew Kirkham, Anthony A. Hyman
Functional analysis of kinetochore assembly in Caenorhabditis elegans.
J Cell Biol, 153(6) 1209-1226 (2001)
---
Andrei V. Popov, Andrei I. Pozniakovsky, Isabelle Arnal, Claude Antony, Anthony J. Ashford, Kazuhisa Kinoshita, Regis Tournebize, Anthony A. Hyman, Eric Karsenti
XMAP215 regulates microtubule dynamics through two distinct domains.
EMBO J, 20(3) 397-410 (2001)
---
Stephan W. Grill, Pierre Gönczy, Ernst H K Stelzer, Anthony A. Hyman
Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo.
Nature, 409(6820) 630-633 (2001)
---
Torsten Wittmann, Anthony A. Hyman, Arshad Desai
The spindle: a dynamic assembly of microtubules and motors.
Nat Cell Biol, 3(1) 28-34 (2001)
---
Pierre Gönczy, Stephan W. Grill, Ernst H K Stelzer, Matthew Kirkham, Anthony A. Hyman
Spindle positioning during the asymmetric first cell division of Caenorhabditis elegans embryos.
Novartis Found Symp, 237 164-175 (2001)
---
Erik Nielsen, Fedor F. Severin, Anthony A. Hyman, Marino Zerial
In vitro reconstitution of endosome motility along microtubules
In: Kinesin protocols. (Eds.) Isabelle Vernos Methods in molecular biology ; 164.,Totowa, USA,Humana Press (2001),133-146 Ch. 12

2000

Pierre Gönczy, Christophe J. Echeverri, Karen Oegema, A Coulson, Steven J. M. Jones, Richard R. Copley, John Duperon, Jeffrey Oegema, Michael Brehm, E Cassin, Eva Hannak, Matthew Kirkham, Silke Pichler, Kathrin Flohrs, A Goessen, Sebastian Leidel, Anne-Marie Alleaume, Cecilie Martin, Nurhan Ozlü, Peer Bork, Anthony A. Hyman
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III.
Nature, 408(6810) 331-336 (2000)
---
V Jantsch-Plunger, Pierre Gönczy, Alper Romano, Heinke Schnabel, Danielle Hamill, Ralf Schnabel, Anthony A. Hyman, Michael Glotzer
CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis.
J Cell Biol, 149(7) 1391-1404 (2000)
---
Isabelle Arnal, Eric Karsenti, Anthony A. Hyman
Structural transitions at microtubule ends correlate with their dynamic properties in Xenopus egg extracts.
J Cell Biol, 149(4) 767-774 (2000)
---
Silke Pichler, Pierre Gönczy, Heinke Schnabel, Andrei I. Pozniakovsky, Anthony J. Ashford, Ralf Schnabel, Anthony A. Hyman
OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos.
Development, 127(10) 2063-2073 (2000)
---
F. J. Ahmad, Jessica Hughey, Torsten Wittmann, Anthony A. Hyman, Marion Greaser, Peter W. Baas
Motor proteins regulate force interactions between microtubules and microfilaments in the axon.
Nat Cell Biol, 2(5) 276-280 (2000)
---
Anthony A. Hyman
Centrosomes: Sic transit gloria centri.
Curr Biol, 10(7) 276-278 (2000)

1999

Pierre Gönczy, Silke Pichler, Matthew Kirkham, Anthony A. Hyman
Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo.
J Cell Biol, 147(1) 135-150 (1999)
---
Arshad Desai, Anthony A. Hyman
Microtubule cytoskeleton: No longer an also Ran.
Curr Biol, 9(18) 704-707 (1999)
---
Pierre Gönczy, Heinke Schnabel, Titus Kaletta, Ana Duran Amores, Anthony A. Hyman, Ralf Schnabel
Dissection of cell division processes in the one cell stage Caenorhabditis elegans embryo by mutational analysis.
J Cell Biol, 144(5) 927-946 (1999)
---
Torsten Wittmann, Anthony A. Hyman
Recombinant p50/dynamitin as a tool to examine the role of dynactin in intracellular processes
In: Mitosis and meiosis. (Eds.) Conly L. Rieder Methods in cell biology ; 61.,Amsterdam, Netherlands,Academic Press (1999),137-143
---
Fedor F. Severin, Ken Kaplan, Peter Sorger, Anthony A. Hyman
In vitro assays for studying Saccharomyces cerevisiae kinetochore activity
In: Mitosis and meiosis. (Eds.) Conly L. Rieder Methods in cell biology ; 61.,Amsterdam, Netherlands,Academic Press (1999),145-153 Ch. 8