Research Groups

* joined first author # joined corresponding author

2021

Lei Xing, Agnieszka Kubik-Zahorodna, Takashi Namba, Anneline Pinson, Marta Florio, Jan Prochazka, Mihail Sarov, Radislav Sedlacek, Wieland Huttner
Expression of human-specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility.
EMBO J, 40(13) Art. No. 107093 (2021)
Open Access   DOI
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Barbara Stepien✳︎, Samir Vaid✳︎#, Ronald Naumann✳︎, Anja Holtz, Wieland Huttner#
Generation of interspecies mouse-rat chimeric embryos by embryonic stem (ES) cell microinjection.
STAR Protoc, 2(2) Art. No. 100494 (2021)
Open Access   DOI
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Anneline Pinson#, Wieland Huttner#
Neocortex expansion in development and evolution-from genes to progenitor cell biology.
Curr Opin Cell Biol, 73 9-18 (2021)
DOI
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Takashi Namba, Christiane Haffner, Wieland Huttner
Ex vivo Tissue Culture Protocols for Studying the Developing Neocortex.
Bio Protoc, 11(10) Art. No. e4031 (2021)
DOI
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Michael Heide#, Wieland Huttner#
Human-Specific Genes, Cortical Progenitor Cells, and Microcephaly.
Cells, 10(5) Art. No. 1209 (2021)
Open Access   DOI
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Felipe Mora-Bermúdez#, Elena Taverna, Wieland Huttner#
From stem and progenitor cells to neurons in the developing neocortex - key differences among hominids.
FEBS J, Art. No. doi: 10.1111/febs.15793 (2021)
DOI
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Dimitri Eigel, Romy Schuster, Max J Männel, Julian Thiele, Martyna J Panasiuk, Laura C Andreae, Carmine Varricchio, Andrea Brancale, Petra B Welzel, Wieland Huttner, Carsten Werner, Ben Newland#, Katherine S. Long#
Sulfonated cryogel scaffolds for focal delivery in ex-vivo brain tissue cultures.
Biomaterials, 271 Art. No. 120712 (2021)
DOI
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Takashi Namba, Jeannette Nardelli, Pierre Gressens#, Wieland Huttner#
Metabolic Regulation of Neocortical Expansion in Development and Evolution.
Neuron, 109(3) 408-419 (2021)
DOI
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Gabriella Shull, Christiane Haffner, Wieland Huttner, Elena Taverna#, Suhasa B Kodandaramaiah#
Manipulation of Single Neural Stem Cells and Neurons in Brain Slices using Robotic Microinjection.
J Vis Exp, (167) Art. No. e61599 (2021)
DOI
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Barbara Stepien✳︎, Samir Vaid✳︎, Wieland Huttner
Length of the Neurogenic Period-A Key Determinant for the Generation of Upper-Layer Neurons During Neocortex Development and Evolution.
Front Cell Dev Biol, 9 Art. No. 676911 (2021)
Open Access   DOI

2020

Tracy A Bedrosian✳︎, Judith Houtman✳︎, Juan Sebastian Eguiguren, Saeed Ghassemzadeh, N Rund, Nicole M Novaresi, Lauren Hu, Sarah L Parylak, Ahmet M Denli, Lynne Randolph-Moore, Takashi Namba, Fred H Gage, Tomohisa Toda
Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis.
EMBO J, 40(3) Art. No. e105819 (2020)
Open Access   DOI
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Barbara Stepien, Ronald Naumann, Anja Holtz, Jussi Helppi, Wieland Huttner, Samir Vaid
Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion.
Curr Biol, 30(21) 4227-4237 (2020)
DOI
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Lei Xing, Nereo Kalebic, Takashi Namba, Samir Vaid, Pauline Wimberger, Wieland Huttner
Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex.
Neuron, 108(6) 1113-1129 (2020)
DOI
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Nereo Kalebic#, Wieland Huttner#
Basal Progenitor Morphology and Neocortex Evolution.
Trends Neurosci., 43(11) 843-853 (2020)
DOI
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Michael Heide#, Christiane Haffner, Ayako Y Murayama, Yoko Kurotaki, Haruka Shinohara, Hideyuki Okano, Erika Sasaki, Wieland Huttner#
Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset.
Science, 369(6503) 546-550 (2020)
DOI
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Samir Vaid#, Wieland Huttner#
Transcriptional Regulators and Human-Specific/Primate-Specific Genes in Neocortical Neurogenesis.
Int J Mol Sci, 21(13) Art. No. 4614 (2020)
Open Access   DOI
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Michael Heide#, Wieland B. Huttner#
Grundlagen und Mechanismen der Neocortex-Expansion.
BIOspektrum, 26(4) 393-397 (2020)
Open Access  
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Nereo Kalebic#, Barbara Langen, Jussi Helppi, Hiroshi Kawasaki, Wieland Huttner#
In Vivo Targeting of Neural Progenitor Cells in Ferret Neocortex by In Utero Electroporation.
J Vis Exp, (159) Art. No. e61171 (2020)
DOI
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József Jászai#, Kristina Thamm, Jana Karbanová, Peggy Janich, Christine A. Fargeas, Wieland Huttner, Denis Corbeil#
Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3.
J Biol Chem, 295(18) 6007-6022 (2020)
DOI
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Ayse Güven, Nereo Kalebic, Katherine S. Long, Marta Florio, Samir Vaid, Holger Brandl, Denise Stenzel, Wieland Huttner
Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex.
Elife, 9 Art. No. e49808 (2020)
Open Access   DOI
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Takashi Namba#, Judit Dóczi, Anneline Pinson, Lei Xing, Nereo Kalebic, Michaela Wilsch-Bräuninger, Katherine S. Long, Samir Vaid, Janelle Lauer, Aliona Bogdanova, Barbara Borgonovo, Anna Shevchenko, Patrick Keller, David N. Drechsel, Teymuras V. Kurzchalia, Pauline Wimberger, Christos Chinopoulos, Wieland Huttner#
Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis.
Neuron, 105(5) 867-881 (2020)
DOI
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Lillian Garrett, Yoon Jeung Chang, Kristina M Niedermeier, Tamara Heermann, Wolfgang Enard, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabe de Angelis, Wieland Huttner, Wolfgang Wurst, Sabine M Hölter
A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.
Transl Psychiatry, 10(1) 66-66 (2020)
Open Access   DOI
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Simone Fietz, Takashi Namba, Holger Kirsten, Wieland Huttner, Robert Lachmann
Signs of reduced basal progenitor levels and cortical neurogenesis in human foetuses with open spina bifida at 11-15 weeks of gestation.
J Neurosci, 40(8) 1766-1777 (2020)
DOI
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Lei Xing#, Wieland Huttner#
Neurotransmitters as Modulators of Neural Progenitor Cell Proliferation During Mammalian Neocortex Development.
Front Cell Dev Biol, 8 Art. No. 391 (2020)
Open Access   DOI
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Katherine Long, Wieland Huttner
Formation of gyri and sulci.
In: Patterning and Cell Type Specification in the Developing CNS and PNS : Comprehensive Developmental Neuroscience. (Eds.) John L.R. Rubenstein,Amsterdam, Netherlands,Academic Press (2020),223-252 Ch. 11
DOI
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Yuko Gonda, Takashi Namba, Carina Hanashima
Beyond Axon Guidance: Roles of Slit-Robo Signaling in Neocortical Formation.
Front Cell Dev Biol, 8 Art. No. 607415 (2020)
Open Access   DOI

2019

Elena Taverna#, Wieland Huttner#
The Golgi Apparatus in Polarized Neuroepithelial Stem Cells and Their Progeny: Canonical and Noncanonical Features.
In: The Golgi apparatus and centriole : functions, interactions and role in disease. (Eds.) Malgorzata Kloc (Results and Problems in Cell Differentiation ; 67).,Cham,Springer International Publishing (2019),359-375 Ch. 15
DOI
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Tatsunori Seki, Tomokatsu Hori, Hajime Miyata, Michiyo Maehara, Takashi Namba
Analysis of proliferating neuronal progenitors and immature neurons in the human hippocampus surgically removed from control and epileptic patients.
Sci Rep, 9(1) Art. No. 18194 (2019)
Open Access   DOI
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Gabriella Shull, Christiane Haffner, Wieland Huttner, Suhasa B Kodandaramaiah, Elena Taverna
Robotic platform for microinjection into single cells in brain tissue.
EMBO Rep, 20(10) Art. No. e47880 (2019)
Open Access   DOI
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Sabina Kanton, Michael James Boyle, Zhisong He, Malgorzata Santel, Anne Weigert, Fátima Sanchís-Calleja, Patricia Guijarro, Leila Sidow, Jonas Simon Fleck, Dingding Han, Zhengzong Qian, Michael Heide, Wieland Huttner, Philipp Khaitovich, Svante Pääbo, Barbara Treutlein, J Gray Camp
Organoid single-cell genomic atlas uncovers human-specific features of brain development.
Nature, 574(7778) 418-422 (2019)
DOI
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Agnes I Lukaszewicz, Cu Nguyen, Elizabeth Melendez, David P Lin, Jia-Ling Teo, Keane K Y Lai, Wieland Huttner, Song-Hai Shi, Michael Kahn
The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or p300.
Cancers (Basel), 11(7) Art. No. E962 (2019)
Open Access   DOI
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Anneline Pinson, Takashi Namba#, Wieland Huttner#
Malformations of Human Neocortex in Development - Their Progenitor Cell Basis and Experimental Model Systems.
Front Cell Neurosci, 13 Art. No. 305 (2019)
Open Access   DOI
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Steven D. Briscoe, Clifton W. Ragsdale
Evolution of the Chordate Telencephalon.
Curr Biol, 29(13) 647-662 (2019)
DOI
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Takashi Namba#, Samir Vaid, Wieland Huttner#
Primate neocortex development and evolution: Conserved versus evolved folding.
J Comp Neurol, 527(10) 1621-1632 (2019)
DOI
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Milos Kostic, Judith Paridaen, Katherine S. Long, Nereo Kalebic, Barbara Langen, Nannette Grübling, Pauline Wimberger, Hiroshi Kawasaki, Takashi Namba#, Wieland Huttner#
YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex.
Cell Rep, 27(4) 1103-1118 (2019)
Open Access   DOI
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Nereo Kalebic, Carlotta Gilardi, Barbara Stepien, Michaela Wilsch-Bräuninger, Katherine S. Long, Takashi Namba, Marta Florio, Barbara Langen, Benoit Lombardot, Anna Shevchenko, Manfred W Kilimann, Hiroshi Kawasaki, Pauline Wimberger, Wieland Huttner
Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology.
Cell Stem Cell, 24(4) 535-550 (2019)
DOI
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Barbara Stepien#, Wieland Huttner#
Transport, Metabolism, and Function of Thyroid Hormones in the Developing Mammalian Brain.
Front Endocrinol (Lausanne), 10 Art. No. 209 (2019)
Open Access   DOI
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Germán Camargo Ortega, Sven Falk, Pia A Johansson, Elise Peyre, Loïc Broix, Sanjeeb Kumar Sahu, William Hirst, Thomas Schlichthaerle, Camino De Juan Romero, Kalina Draganova, Stanislav Vinopal, Kaviya Chinnappa, Anna Gavranovic, Tugay Karakaya, Thomas Steininger, Juliane Merl-Pham, Regina Feederle, Wei Shao, Song-Hai Shi, Stefanie M Hauck, Ralf Jungmann, Frank Bradke, Víctor Borrell, Arie Geerlof, Simone Reber, Vijay K Tiwari, Wieland Huttner, Michaela Wilsch-Bräuninger, Laurent Nguyen, Magdalena Götz
The centrosome protein AKNA regulates neurogenesis via microtubule organization.
Nature, 567(7746) 113-117 (2019)
DOI
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Katherine S. Long#, Wieland Huttner#
How the extracellular matrix shapes neural development.
Open Biol, 9(1) Art. No. 180216 (2019)
Open Access   DOI
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Donald Singer, Kristina Thamm, Heng Zhuang, Jana Karbanová, Yan Gao, Jemma Victoria Walker, Heng Jin, Xiangnan Wu, Clarissa R Coveney, Pauline Marangoni, Dongmei Lu, Portia Rebecca Clare Grayson, Tulay Gulsen, Karen J Liu, Stefano Ardu, Angus Kt Wann, Shouqing Luo, Alexander C. Zambon, Anton M. Jetten, Christopher Tredwin, Ophir D. Klein, Massimo Attanasio, Peter Carmeliet, Wieland Huttner, Denis Corbeil#, Bing Hu#
Prominin-1 controls stem cell activation by orchestrating ciliary dynamics.
EMBO J, 38(2) Art. No. e99845 (2019)
DOI
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Kristina Thamm, Deimantė Šimaitė, Jana Karbanová, Vicente Bermúdez, Doreen Reichert, Anne Morgenstern, Martin Bornhäuser, Wieland Huttner, Michaela Wilsch-Bräuninger, Denis Corbeil
Prominin-1 (CD133) modulates the architecture and dynamics of microvilli.
Traffic, 20(1) 39-60 (2019)
DOI
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Jan Fischer✳︎, Michael Heide✳︎#, Wieland Huttner#
Genetic Modification of Brain Organoids.
Front Cell Neurosci, 13 Art. No. 558 (2019)
Open Access   DOI
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Steven D. Briscoe
Field Homology: Still a Meaningless Concept.
Brain Behav. Evol., 93(1) 1-3 (2019)
DOI

2018

Nereo Kalebic, Carlotta Gilardi, Mareike Albert, Takashi Namba, Katherine S. Long, Milos Kostic, Barbara Langen, Wieland Huttner
Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex.
Elife, 7 Art. No. e41241 (2018)
Open Access   DOI
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Samir Vaid, J Gray Camp, Lena Hersemann, Christina Eugster Oegema, Anne-Kristin Heninger, Sylke Winkler, Holger Brandl, Mihail Sarov, Barbara Treutlein, Wieland Huttner#, Takashi Namba#
A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex.
Development, 145(20) Art. No. dev169276 (2018)
DOI
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Steven D. Briscoe, Clifton W. Ragsdale
Homology, neocortex, and the evolution of developmental mechanisms.
Science, 362(6411) 190-193 (2018)
DOI
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Felipe Mora-Bermudez, Wieland B. Huttner
Centrosomes in asymmetric cell division and neocortical development.
In: Encyclopedia of Life Sciences (eLS). (Eds.) Mauro Maccarrone,Chichester,John Wiley & Sons Ltd. (2018),1-9
DOI
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Katherine S. Long, Ben Newland, Marta Florio, Nereo Kalebic, Barbara Langen, Anna Kolterer, Pauline Wimberger, Wieland Huttner
Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex.
Neuron, 99(4) 702-719 (2018)
DOI
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Michael Heide, Wieland B. Huttner, Felipe Mora-Bermúdez
Brain organoids as models to study human neocortex development and evolution.
Curr Opin Cell Biol, 55 8-16 (2018)
DOI
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Stefania Tavano, Elena Taverna, Nereo Kalebic, Christiane Haffner, Takashi Namba, Andreas Dahl, Michaela Wilsch-Bräuninger, Judith Paridaen#, Wieland B. Huttner#
Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7.
Neuron, 97(6) 1299-1314 (2018)
DOI
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Marta Florio✳︎, Michael Heide✳︎, Anneline Pinson, Holger Brandl, Mareike Albert, Sylke Winkler, Pauline Wimberger, Wieland B. Huttner#, Michael Hiller#
Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.
Elife, 7 Art. No. e32332 (2018)
Open Access   PDF    DOI
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Mareike Albert#, Wieland Huttner#
Epigenetic and Transcriptional Pre-patterning-An Emerging Theme in Cortical Neurogenesis.
Front Neurosci, 12 Art. No. 359 (2018)
Open Access   DOI

2017

J M Wasielewska, L Grönnert, N Rund, L Donix, R Rust, Alex Sykes, A Hoppe, Axel Roers, Gerd Kempermann, T L Walker
Mast cells increase adult neural precursor proliferation and differentiation but this potential is not realized in vivo under physiological conditions.
Sci Rep, 7(1) Art. No. 17859 (2017)
Open Access   DOI
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Michael Heide, Katherine Long, Wieland B. Huttner
Novel gene function and regulation in neocortex expansion.
Curr Opin Cell Biol, 49 22-30 (2017)
DOI
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Mareike Albert#, Nereo Kalebic, Marta Florio, Naharajan Lakshmanaperumal, Christiane Haffner, Holger Brandl, Ian Henry, Wieland B. Huttner#
Epigenome profiling and editing of neocortical progenitor cells during development.
EMBO J, 36(17) 2642-2658 (2017)
DOI
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Sheik Pran Babu Sardar Pasha, Robert Münch, Patrick Schäfer, Peter Oertel, Alex Sykes, Yiqing Zhu, Mike Karl
Retinal cell death dependent reactive proliferative gliosis in the mouse retina.
Sci Rep, 7(1) Art. No. 9517 (2017)
Open Access   DOI
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Tobias Boothe, Lennart Hilbert, Michael Heide, Lea Berninger, Wieland B. Huttner, Vasily Zaburdaev, Nadine Vastenhouw, Eugene W Myers, David N. Drechsel, Jochen Rink
A tunable refractive index matching medium for live imaging cells, tissues and model organisms.
Elife, 6 Art. No. e27240 (2017)
Open Access   DOI
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Takashi Namba, Wieland B. Huttner
Neural progenitor cells and their role in the development and evolutionary expansion of the neocortex.
Wiley Interdiscip Rev Dev Biol, 6(1) Art. No. e256 (2017)
DOI
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Marta Florio, Víctor Borrell, Wieland B. Huttner
Human-specific genomic signatures of neocortical expansion.
Curr Opin Neurobiol, 42 33-44 (2017)
DOI
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Stefania Tavano, Wieland B. Huttner
The Cell Biology of Neural Stem and Progenitor Cells and Neocortex Expansion in Development and Evolution
In: Essentials of noncoding RNA in neuroscience : ontogenetics, plasticity of the vertebrate brain. (Eds.) Davide De Pietri Tonelli,Amsterdam, Netherlands,Academic Press (2017),81-99
DOI
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Andreas Ettinger, Yoichi Kosodo, Wieland B. Huttner
Specific membrane dynamics during neural stem cell division.
Methods Cell Biol, 137 143-172 (2017)
DOI
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Nereo Kalebic, Katherine S. Long, Wieland B. Huttner
Neocortex expansion in development and evolution: the cell biology of neural stem and progenitor cells and the impact of human-specific gene expression.
In: Evolution of Nervous Systems . Vol. 3 : The nervous systems of non-human primates. (Eds.) Jon H Kaas,Amsterdam, Netherlands,Elsevier (2017),73-89

2016

Ayse Güven
The role of Sox9 and extracellular matrix in the development and evolutionary expansion of the neocortex
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2016)
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Marta Florio, Takashi Namba, Svante Pääbo, Michael Hiller, Wieland B. Huttner
A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification
Sci Adv, 2(12) Art. No. e1601941 (2016)
Open Access   PDF   
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Kristina Thamm, Sylvi Graupner, Carsten Werner, Wieland B. Huttner, Denis Corbeil
Monoclonal Antibodies 13A4 and AC133 Do Not Recognize the Canine Ortholog of Mouse and Human Stem Cell Antigen Prominin-1 (CD133).
PLoS ONE, 11(10) Art. No. e0164079 (2016)
Open Access   PDF    DOI
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Felipe Mora-Bermúdez, Farhath Badsha, Sabina Kanton, J Gray Camp, Benjamin Vernot, Kathrin Köhler, Birger Voigt, Keisuke Okita, Tomislav Maricic, Zhisong He, Robert Lachmann, Svante Pääbo, Barbara Treutlein, Wieland B. Huttner
Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development.
Elife, 5 Art. No. e18683 (2016)
Open Access   PDF    DOI
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M Gai, Federico Bianchi, Cristiana Vagnoni, Fiammetta Vernì, Silvia Bonaccorsi, Selina Pasquero, G E Berto, F Sgrò, A M A Chiotto, Laura Annaratone, Anna Sapino, Anna Bergo, Nicoletta Landsberger, Jacqueline Bond, Wieland B. Huttner, F Di Cunto
ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.
EMBO Rep, 17(10) 1396-1409 (2016)
DOI
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Felipe Mora-Bermúdez
Costa Rica: World's last in vitro fertilization ban falls.
Nature, 536(7616) 274-274 (2016)
DOI
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Michael Heide, Marta Florio, Wieland B. Huttner
Die Rolle humanspezifischer Gene in der Gehirnentwicklung und -evolution
BIOspektrum, 22(4) 352-355 (2016)
DOI
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Michaela Wilsch-Bräuninger, Marta Florio, Wieland B. Huttner
Neocortex expansion in development and evolution - from cell biology to single genes.
Curr Opin Neurobiol, 39 122-132 (2016)
DOI
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Christian Lange, Miguel Turrero Garcia, Ilaria Decimo, Francesco Bifari, Guy Eelen, Annelies Quaegebeur, Ruben Boon, Hui Zhao, Bram Boeckx, Junlei Chang, Christine Wu, Ferdinand Le Noble, Diether Lambrechts, Mieke Dewerchin, Calvin J Kuo, Wieland B. Huttner, Peter Carmeliet
Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.
EMBO J, 35(9) 924-941 (2016)
DOI
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Berta Terré, Gabriele Piergiovanni, Sandra Segura-Bayona, Gabriel Gil-Gómez, Sameh A Youssef, Camille Stephan-Otto Attolini, Michaela Wilsch-Bräuninger, Carole Jung, Ana M Rojas, Marko Marjanović, Philip A Knobel, Lluís Palenzuela, Teresa López-Rovira, Stephen Forrow, Wieland B. Huttner, Miguel A Valverde, Alain de Bruin, Vincenzo Costanzo, Travis H Stracker
GEMC1 is a critical regulator of multiciliated cell differentiation.
EMBO J, 35(9) 942-960 (2016)
DOI
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F Sgrò, Federico Bianchi, M Falcone, G Pallavicini, M Gai, A M A Chiotto, G E Berto, E Turco, Yoon Jeung Chang, Wieland B. Huttner, F Di Cunto
Tissue-specific control of midbody microtubule stability by Citron kinase through modulation of TUBB3 phosphorylation.
Cell Death Differ, 23(5) 801-813 (2016)
DOI
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Yoko Arai, Wieland B. Huttner, Federico Calegari
Neural stem cells
In: Regenerative Medicine - from Protocol to Patient : Stem Cell Science and Technology . (Eds.) Gustav Steinhoff,Cham,Springer International Publishing (2016),169-208 Ch. 7
DOI
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Marta Florio, Takashi Namba, Katherine Long
The Tortuous Routes of Migrating Neurons in the Folding Neocortex.
J Neurosci, 36(14) 3887-3889 (2016)
DOI
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Nereo Kalebic, Elena Taverna, Stefania Tavano, Fong Kuan Wong, Dana Suchold, Sylke Winkler, Wieland B. Huttner, Mihail Sarov
CRISPR/Cas9-induced disruption of gene expression in mouse embryonic brain and single neural stem cells in vivo.
EMBO Rep, 17(3) 338-348 (2016)
Open Access   PDF    DOI
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Stefania Tavano
Molecular and cellular mechanisms underlying the role of Insm1 in the generation of basal progenitor cells
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2016)
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Eric Lewitus, Iva Kelava, Alex T. Kalinka, Pavel Tomancak, Wieland B. Huttner
Comment on "Cortical folding scales universally with surface area and thickness, not number of neurons".
Science, 351(6275) 825-825 (2016)
PDF    DOI
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Miguel Turrero García, Yoon Jeung Chang, Yoko Arai, Wieland B. Huttner
S-phase duration is the main target of cell cycle regulation in neural progenitors of developing ferret neocortex.
J Comp Neurol, 524(3) 456-470 (2016)
DOI
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Elena Taverna, Felipe Mora-Bermúdez, Paulina J. Strzyz, Marta Florio, Jaroslav Icha, Christiane Haffner, Caren Norden, Michaela Wilsch-Bräuninger, Wieland B. Huttner
Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells.
Sci Rep, 6 Art. No. 21206 (2016)
Open Access   PDF    DOI
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Sandrine Passemard, Alain Verloes, Thierry Billette de Villemeur, Odile Boespflug-Tanguy, Karen Hernandez, Marion Laurent, Bertrand Isidor, Corinne Alberti, Nathalie Pouvreau, Séverine Drunat, Bénédicte Gérard, Vincent El Ghouzzi, Jorge Gallego, Monique Elmaleh-Bergès, Wieland B. Huttner, Stephan Eliez, Pierre Gressens, Marie Schaer
Abnormal spindle-like microcephaly-associated (ASPM) mutations strongly disrupt neocortical structure but spare the hippocampus and long-term memory.
Cortex, 74 158-176 (2016)
DOI

2015

J Gray Camp, Farhath Badsha, Marta Florio, Sabina Kanton, Tobias Gerber, Michaela Wilsch-Bräuninger, Eric Lewitus, Alex Sykes, Wulf Hevers, Madeline Lancaster, Jürgen A. Knoblich, Robert Lachmann, Svante Pääbo, Wieland B. Huttner, Barbara Treutlein
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development.
Proc Natl Acad Sci U.S.A., 112(51) 15672-15677 (2015)
Open Access   PDF    DOI
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Felipe Mora-Bermúdez, Wieland B. Huttner
Novel insights into mammalian embryonic neural stem cell division: focus on microtubules.
Mol Biol Cell, 26(24) 4302-4306 (2015)
DOI
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Marta Florio
Transcriptional Signatures of Neocortical Expansion - Evolutionary Role of the Human-Specific Gene ARHGAP11B
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2015)
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Edo Dzafic, Paulina J. Strzyz, Michaela Wilsch-Bräuninger, Caren Norden
Centriole Amplification in Zebrafish Affects Proliferation and Survival but Not Differentiation of Neural Progenitor Cells.
Cell Rep, 13(1) 168-182 (2015)
Open Access   PDF    DOI
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Fong Kuan Wong, Jifeng Fei, Felipe Mora-Bermúdez, Elena Taverna, Christiane Haffner, Jun Fu, Konstantinos Anastassiadis, A Francis Stewart, Wieland B. Huttner
Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex.
PLoS Biol, 13(8) Art. No. e1002217 (2015)
Open Access   PDF    DOI
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Mareike Albert, Wieland B. Huttner
Clever space saving-how the cerebral cortex folds.
EMBO J, 34(14) 1845-1847 (2015)
DOI
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Wieland B. Huttner
Stem cells: slow and steady wins the race.
Nat Neurosci, 18(5) 613-614 (2015)
DOI
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Marta Florio, Mareike Albert, Elena Taverna, Takashi Namba, Holger Brandl, Eric Lewitus, Christiane Haffner, Alex Sykes, Fong Kuan Wong, Jula Peters, E. Guhr, Sylvia Klemroth, Kay Prüfer, Janet Kelso, Ronald Naumann, Ina Nüsslein, Andreas Dahl, Robert Lachmann, Svante Pääbo, Wieland B. Huttner
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion.
Science, 347(6229) 1465-1470 (2015)
DOI
---
Eric Lewitus, Wieland B. Huttner
Neurodevelopmental LincRNA Microsyteny Conservation and Mammalian Brain Size Evolution.
PLoS ONE, 10(7) Art. No. e0131818 (2015)
Open Access   PDF    DOI
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Yoko Arai, Julio Sampaio, Michaela Wilsch-Bräuninger, Andreas Ettinger, Christiane Haffner, Wieland B. Huttner
Lipidome of midbody released from neural stem and progenitor cells during mammalian cortical neurogenesis.
Front Cell Neurosci, 9 Art. No. 325 (2015)
Open Access   PDF    DOI
---
Judith Paridaen, Wieland B. Huttner, Michaela Wilsch-Bräuninger
Analysis of primary cilia in the developing mouse brain.
Methods Cell Biol, 127 93-129 (2015)
DOI

2014

Eric Lewitus#, Iva Kelava, Alex T. Kalinka, Pavel Tomancak, Wieland B. Huttner#
An Adaptive Threshold in Mammalian Neocortical Evolution.
PLoS Biol, 12(11) Art. No. e1002000 (2014)
Open Access   PDF    DOI
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Elena Taverna, Magdalena Götz, Wieland B. Huttner
The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex.
Annu Rev Cell Dev Biol, 30 465-502 (2014)
DOI
---
Jana Karbanová, Jan Laco, Anne-Marie Marzesco, Peggy Janich, Magda Voborníková, Jaroslav Mokrý, Christine A. Fargeas, Wieland B. Huttner, Denis Corbeil
Human prominin-1 (CD133) is detected in both neoplastic and non-neoplastic salivary gland diseases and released into saliva in a ubiquitinated form.
PLoS ONE, 9(6) Art. No. e98927 (2014)
Open Access   DOI
---
Felipe Mora-Bermúdez, Fumio Matsuzaki, Wieland B. Huttner
Specific polar subpopulations of astral microtubules control spindle orientation and symmetric neural stem cell division.
Elife, 3 Art. No. e02875 (2014)
Open Access   PDF    DOI
---
Fong Kuan Wong
Generation of basal radial glia in the embryonic mouse dorsal telencephalon
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2014)
---
Marta Florio, Wieland B. Huttner
Neural progenitors, neurogenesis and the evolution of the neocortex.
Development, 141(11) 2182-2194 (2014)
DOI
---
Alicia Tapias, Zhong-Wei Zhou, Yue Shi, Zechen Chong, Pei Wang, Marco Groth, Matthias Platzer, Wieland Huttner, Zdenko Herceg, Yun-Gui Yang, Zhao-Qi Wang
Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions.
Cell Stem Cell, 14(5) 632-643 (2014)
DOI
---
Fong Kuan Wong, Christiane Haffner, Wieland B. Huttner, Elena Taverna
Microinjection of membrane-impermeable molecules into single neural stem cells in brain tissue.
Nat Protoc, 9(5) 1170-1182 (2014)
DOI
---
Judith Paridaen, Wieland B. Huttner
Neurogenesis during development of the vertebrate central nervous system.
EMBO Rep, 15(4) 351-364 (2014)
DOI
---
Jifeng Fei, Christiane Haffner, Wieland B. Huttner
3' UTR-Dependent, miR-92-Mediated Restriction of Tis21 Expression Maintains Asymmetric Neural Stem Cell Division to Ensure Proper Neocortex Size.
Cell Rep, 7(2) 398-411 (2014)
Open Access   DOI
---
Iva Kelava, Wieland B. Huttner
Neural progenitors and evolution of mammalian neocortex.
In: Stem Cells : From Basic Research to Therapy ; Vol. 1, Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms. (Eds.) Federico Calegari, Claudia Waskow,Boca Raton, USA,CRC Press (2014),213-257 Ch. 8
---
Denise Stenzel, Michaela Wilsch-Bräuninger, Fong Kuan Wong, Heike Heuer, Wieland B. Huttner
Integrin αvβ3 and thyroid hormones promote expansion of progenitors in embryonic neocortex.
Development, 141(4) 795-806 (2014)
PDF    DOI
---
Marie-Theres Schmid, Franziska Weinandy, Michaela Wilsch-Bräuninger, Wieland B. Huttner, Silvia Cappello, Magdalena Götz
The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration.
Front Cell Neurosci, 8 Art. No. 215 (2014)
Open Access   DOI
---
Davide De Pietri Tonelli, Yoanne M Clovis, Wieland B. Huttner
Detection and monitoring of microRNA expression in developing mouse brain and fixed brain cryosections.
Methods Mol Biol, 1092 31-42 (2014)
DOI

2013

Wieland B. Huttner, Iva Kelava, Eric Lewitus
Progenitor networking in the fetal primate neocortex.
Neuron, 80(2) 259-262 (2013)
DOI
---
Judith Paridaen, Michaela Wilsch-Bräuninger, Wieland B. Huttner
Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division.
Cell, 155(2) 333-344 (2013)
DOI
---
Joanna Kalucka, Andreas Ettinger, Kristin Franke, Soulafa Mamlouk, Rashim Pal Singh, Katja Farhat, Antje Muschter, Susanne Olbrich, Georg Breier, Dörthe M Katschinski, Wieland Huttner, Alexander Weidemann, Ben Wielockx
Loss of epithelial hypoxia-inducible factor prolyl hydroxylase 2 accelerates skin wound healing in mice.
Mol Cell Biol, 33(17) 3426-3438 (2013)
DOI
---
Eric Lewitus, Iva Kelava, Wieland B. Huttner
Conical expansion of the outer subventricular zone and the role of neocortical folding in evolution and development
Front Hum Neurosci, 7 Art. No. 424 (2013)
Open Access   DOI
---
Denise Stenzel, Wieland B. Huttner
Role of maternal thyroid hormones in the developing neocortex and during human evolution
Front Neuroanat, 7 Art. No. 19 (2013)
Open Access   DOI
---
Iva Kelava, Eric Lewitus, Wieland B. Huttner
The secondary loss of gyrencephaly as an example of evolutionary phenotypical reversal
Front Neuroanat, 7 Art. No. 16 (2013)
Open Access   DOI
---
József Jászai, Sylvi Graupner, Elly M. Tanaka, Richard Funk, Wieland B. Huttner, Michael Brand, Denis Corbeil
Spatial distribution of prominin-1 (CD133)-positive cells within germinative zones of the vertebrate brain
PLoS ONE, 8(5) Art. No. e63457 (2013)
Open Access   DOI
---
Chun-Ting Chen, Andreas Ettinger, Wieland B. Huttner, Stephen J Doxsey
Resurrecting remnants: the lives of post-mitotic midbodies
Trends Cell Biol, 23(3) 118-128 (2013)
DOI
---
Zoltan Maliga, Magno Junqueira, Yusuke Toyoda, Andreas Ettinger, Felipe Mora-Bermúdez, Robin Klemm, Andrej Vasilj, E. Guhr, Itziar Ibarlucea-Benitez, Ina Poser, Enzio Bonifacio, Wieland B. Huttner, Andrej Shevchenko, Anthony Hyman
A genomic toolkit to investigate kinesin and myosin motor function in cells.
Nat Cell Biol, 15(3) 325-334 (2013)
DOI
---
Felipe Mora-Bermúdez, Miguel Turrero García, Wieland B. Huttner
Stem cells: Neural stem cells in cerebral cortex development.
In: Neuroscience in the 21st Century : from basic to clinical. (Eds.) Donald W. Pfaff,New York,Springer (2013),137-159 Ch. 6
DOI
---
A.M. Sykes, Wieland B. Huttner
Prominin-1 (CD133) and the cell biology of neural progenitors and their progeny.
In: Prominin-1 (CD133): New Insights on Stem and Cancer Stem Cell Biology. (Eds.) Denis Corbeil Advances in Experimental Medicine and Biology ; 777.,New York,Springer (2013),89-98 Ch. 6
DOI
---
Eric Lewitus✳︎, Iva Kelava✳︎, Alex T. Kalinka, Pavel Tomancak, Wieland B. Huttner
An Adaptive Threshold in Mammalian Neocortical Evolution
bioRxiv, Art. No. doi: 10.1101/001289 (2013)
Open Access   PDF   

2012

Iva Kelava, Wieland B. Huttner
Neurogenesis in the developing mammalian neocortex.
In: Encyclopedia of Life Sciences (eLS).,Chichester,John Wiley & Sons Ltd. (2012)
DOI
---
Yoanne M Clovis, Wolfgang Enard, Federica Marinaro, Wieland B. Huttner, Davide De Pietri Tonelli
Convergent repression of Foxp2 3'UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons.
Development, 139(18) 3332-3342 (2012)
DOI
---
Simone Fietz, Robert Lachmann, Holger Brandl, Martin Kircher, Nikolay Samusik, Roland Schröder, Naharajan Lakshmanaperumal, Ian Henry, Johannes Vogt, Axel Riehn, Wolfgang Distler, Robert Nitsch, Wolfgang Enard, Svante Pääbo, Wieland B. Huttner
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal.
Proc Natl Acad Sci U.S.A., 109(29) 11836-11841 (2012)
DOI
---
Annette Gärtner, Eugenio F Fornasiero, Sebastian Munck, Krist'l Vennekens, Eve Seuntjens, Wieland B. Huttner, Flavia Valtorta, Carlos G Dotti
N-cadherin specifies first asymmetry in developing neurons.
EMBO J, 31(8) 1893-1903 (2012)
PDF    DOI
---
Elena Taverna, Christiane Haffner, Rainer Pepperkok, Wieland B. Huttner
A new approach to manipulate the fate of single neural stem cells in tissue.
Nat Neurosci, 15(2) 329-337 (2012)
DOI
---
Iva Kelava, Isabel Reillo, Ayako Y Murayama, Alex T. Kalinka, Denise Stenzel, Pavel Tomancak, Fumio Matsuzaki, Cécile Lebrand, Erika Sasaki, Jens C Schwamborn, Hideyuki Okano, Wieland B. Huttner, Víctor Borrell
Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus.
Cereb Cortex, 22(2) 469-481 (2012)
PDF    DOI
---
Michaela Wilsch-Bräuninger, Jula Peters, Judith Paridaen, Wieland B. Huttner
Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination.
Development, 139(1) 95-105 (2012)
PDF    DOI

2011

Maki Asami, Gregor A Pilz, Jovica Ninkovic, Leanne Godinho, Timm Schroeder, Wieland B. Huttner, Magdalena Götz
The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex
Development, 138(23) 5067-5078 (2011)
DOI
---
Nicola Bauer, Michaela Wilsch-Bräuninger, Jana Karbanová, Ana-Violeta Fonseca, Doreen Strauss, Daniel Freund, Christoph Thiele, Wieland B. Huttner, Martin Bornhäuser, Denis Corbeil
Haematopoietic stem cell differentiation promotes the release of prominin-1/CD133-containing membrane vesicles-a role of the endocytic-exocytic pathway
EMBO Mol Med, 3(7) 398-409 (2011)
DOI
---
Ewa Missol-Kolka, Jana Karbanová, Peggy Janich, Michael Haase, Christine A. Fargeas, Wieland B. Huttner, Denis Corbeil
Prominin-1 (CD133) is not restricted to stem cells located in the basal compartment of murine and human prostate.
Prostate, 71(3) 254-267 (2011)
PDF    DOI
---
Simone Fietz, Wieland B. Huttner
Cortical progenitor expansion, self-renewal and neurogenesis-a polarized perspective.
Curr Opin Neurobiol, 21(1) 23-35 (2011)
PDF    DOI
---
Andreas Ettinger, Michaela Wilsch-Bräuninger, Anne-Marie Marzesco, Marc Bickle, Annett Lohmann, Zoltan Maliga, Jana Karbanová, Denis Corbeil, Anthony A. Hyman, Wieland B. Huttner
Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour.
Nat Commun, 2 Art. No. 503 (2011)
Open Access   PDF    DOI
---
Yoko Arai, Jeremy N. Pulvers, Christiane Haffner, Britta Schilling, Ina Nüsslein, Federico Calegari, Wieland B. Huttner
Neural stem and progenitor cells shorten S-phase on commitment to neuron production.
Nat Commun, 2 Art. No. 154 (2011)
Open Access   DOI
---
József Jászai, Christine A. Fargeas, Sylvi Graupner, Elly M. Tanaka, Michael Brand, Wieland B. Huttner, Denis Corbeil
Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species.
PLoS ONE, 6(3) Art. No. e17590 (2011)
Open Access   DOI

2010

Andreas Ettinger
Release of post-abscission midbodies from stem and cancer cells and potential links to differentiation
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2010)
---
Elena Taverna, Wieland B. Huttner
Neural progenitor nuclei IN motion.
Neuron, 67(6) 906-914 (2010)
PDF    DOI
---
Jeremy N. Pulvers, Jaroslaw Bryk, Jennifer L. Fish, Michaela Wilsch-Bräuninger, Yoko Arai, Dora Schreier, Ronald Naumann, Jussi Helppi, Bianca Habermann, Johannes Vogt, Robert Nitsch, Attila Toth, Wolfgang Enard, Svante Pääbo, Wieland B. Huttner
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline.
Proc Natl Acad Sci U.S.A., 107(38) 16595-16600 (2010)
PDF    DOI
---
Simone Fietz, Iva Kelava, Johannes Vogt, Michaela Wilsch-Bräuninger, Denise Stenzel, Jennifer L. Fish, Denis Corbeil, Axel Riehn, Wolfgang Distler, Robert Nitsch, Wieland B. Huttner
OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling.
Nat Neurosci, 13(6) 690-699 (2010)
PDF    DOI
---
Judith Schenk
Interkinetic nuclear migration and centrosome positioning in mammalian neural progenitors : the role of non-muscle myosin II
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2010)
---
Denis Corbeil, Anne-Marie Marzesco, Michaela Wilsch-Bräuninger, Wieland B. Huttner
The intriguing links between prominin-1 (CD133), cholesterol-based membrane microdomains, remodeling of apical plasma membrane protrusions, extracellular membrane particles, and (neuro)epithelial cell differentiation.
FEBS Lett, 584(9) 1659-1664 (2010)
PDF    DOI
---
József Jászai, Lilla M. Farkas, Christine A. Fargeas, Peggy Janich, Michael Haase, Wieland B. Huttner, Denis Corbeil
Prominin-2 is a novel marker of distal tubules and collecting ducts of the human and murine kidney.
Histochem Cell Biol, 133(5) 527-539 (2010)
PDF    DOI
---
Alessio Attardo✳︎, Klaus Fabel✳︎, Julia Krebs, Wulf Haubensak, Wieland B. Huttner✳︎, Gerd Kempermann✳︎
Tis21 expression marks not only populations of neurogenic precursor cells but also new postmitotic neurons in adult hippocampal neurogenesis.
Cereb Cortex, 20(2) 304-314 (2010)
PDF    DOI
---
Jésica Díaz-Vera, Yézer G Morales, Juan R Hernández-Fernaud, Marcial Camacho, Mónica S Montesinos, Federico Calegari, Wieland B. Huttner, Ricardo Borges, José D Machado
Chromogranin B gene ablation reduces the catecholamine cargo and decelerates exocytosis in chromaffin secretory vesicles.
J Neurosci, 30(3) 950-957 (2010)
PDF    DOI
---
Denis Corbeil, Anne-Marie Marzesco, Christine A. Fargeas, Wieland B. Huttner
Prominin-1: a distinct cholesterol-binding membrane protein and the organisation of the apical plasma membrane of epithelial cells.
Subcell Biochem, 51 399-423 (2010)
DOI
---
Stefanie Obermüller✳︎, Federico Calegari✳︎, Angus King, Anders Lindqvist, Ingmar Lundquist, Albert Salehi, Maura Francolini, Patrizia Rosa, Patrik Rorsman, Wieland B. Huttner#, Sebastian Barg#
Defective secretion of islet hormones in chromogranin-B deficient mice.
PLoS ONE, 5(1) Art. No. e8936 (2010)
Open Access   PDF    DOI

2009

Kueifang Chung, Flavie Sicard, Vladimir Vukicevic, Andreas Hermann, Alexander Storch, Wieland B. Huttner, Stefan R. Bornstein, Monika Ehrhart-Bornstein
Isolation of neural crest derived chromaffin progenitors from adult adrenal medulla.
Stem Cells, 27(10) 2602-2613 (2009)
PDF    DOI
---
Tom Kowalczyk✳︎, Adria Pontious✳︎, Chris Englund, Ray A. M. Daza, Francesco Bedogni, Rebecca Hodge, Alessio Attardo, Chris Bell, Wieland B. Huttner, Robert F Hevner
Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex.
Cereb Cortex, 19(10) 2439-2450 (2009)
PDF    DOI
---
Judith Schenk, Michaela Wilsch-Bräuninger, Federico Calegari, Wieland B. Huttner
Myosin II is required for interkinetic nuclear migration of neural progenitors.
Proc Natl Acad Sci U.S.A., 106(38) 16487-16492 (2009)
PDF    DOI
---
Christian Lange, Wieland B. Huttner, Federico Calegari
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors.
Cell Stem Cell, 5(3) 320-331 (2009)
PDF    DOI
---
Jifeng Fei, Wieland B. Huttner
Nonselective sister chromatid segregation in mouse embryonic neocortical precursor cells.
Cereb Cortex, 19(Suppl 1) 49-54 (2009)
PDF    DOI
---
Sidney B Cambridge, Daniel Geissler, Federico Calegari, Konstantinos Anastassiadis, Mazahir T Hasan, A. Francis Stewart, Wieland B. Huttner, Volker Hagen, Tobias Bonhoeffer
Doxycycline-dependent photoactivated gene expression in eukaryotic systems.
Nat Methods, 6(7) 527-531 (2009)
PDF    DOI
---
Anne-Marie Marzesco, Felipe Mora-Bermudez, Wieland B. Huttner
Neurogenesis in G minor.
Nat Neurosci, 12(6) 669-671 (2009)
PDF    DOI
---
Denis Corbeil✳︎, Angret Joester✳︎, Christine A. Fargeas, József Jászai, Jeremy Garwood, Andrea Hellwig, Hauke B Werner, Wieland B. Huttner
Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells.
Glia, 57(8) 860-874 (2009)
PDF    DOI
---
Jeremy N. Pulvers, Wieland B. Huttner
Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors.
Development, 136(11) 1859-1868 (2009)
PDF    DOI
---
Kanako Saito✳︎, Veronique Dubreuil✳︎, Yoko Arai, Michaela Wilsch-Bräuninger, Dominik Schwudke, Gesine Saher, Takaki Miyata, Georg Breier, Christoph Thiele, Andrej Shevchenko, Klaus-Armin Nave, Wieland B. Huttner
Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis.
Proc Natl Acad Sci U.S.A., 106(20) 8350-8355 (2009)
PDF    DOI
---
Yoichi Kosodo, Wieland B. Huttner
Basal process and cell divisions of neural progenitors in the developing brain.
Dev Growth Differ, 51(3) 251-261 (2009)
PDF    DOI
---
Anne-Marie Marzesco, Michaela Wilsch-Bräuninger, Veronique Dubreuil, Peggy Janich, Katja Langenfeld, Christoph Thiele, Wieland B. Huttner, Denis Corbeil
Release of extracellular membrane vesicles from microvilli of epithelial cells is enhanced by depleting membrane cholesterol.
FEBS Lett, 583(5) 897-902 (2009)
PDF    DOI
---
Serena Zacchigna, Hideyasu Oh, Michaela Wilsch-Bräuninger, Ewa Missol-Kolka, József Jászai, Sandra Jansen, Naoyuki Tanimoto, Felix Tonagel, Mathias Seeliger, Wieland B. Huttner, Denis Corbeil, Mieke Dewerchin, Stefan Vinckier, Lieve Moons, Peter Carmeliet
Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration.
J Neurosci, 29(7) 2297-2308 (2009)
PDF    DOI
---
Jeremy N. Pulvers
The roles of the genes Aspm and Brcal in the development of the mouse neocortex
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2009)
---
Marat Gorivodsky, Mahua Mukhopadhyay, Michaela Wilsch-Bräuninger, Matthew Phillips, Andreas Teufel, Changmee Kim, Nasir Malik, Wieland B. Huttner, Heiner Westphal
Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain.
Dev Biol, 325(1) 24-32 (2009)
PDF    DOI
---
Kuixing Zhang, Fangwen Rao, Brinda K. Rana, Jiaur R. Gayen, Federico Calegari, Angus King, Patrizia Rosa, Wieland B. Huttner, Mats Stridsberg, Manjula Mahata, Sucheta Vaingankar, Vafa Mahboubi, Rany M Salem, Juan L Rodriguez-Flores, Maple M Fung, Douglas W Smith, Nicholas J Schork, Michael G Ziegler, Laurent Taupenot, Sushil K Mahata, Daniel T O'Connor
Autonomic function in hypertension: Role of genetic variation at the catecholaminestorage vesicle protein chromogranin B (CHGB).
Circ Cardiovasc Genet, 2(1) 46-56 (2009)
PDF    DOI

2008

Lilla M. Farkas, Wieland B. Huttner
The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain development.
Curr Opin Cell Biol, 20(6) 707-715 (2008)
PDF    DOI
---
Davide De Pietri Tonelli, Jeremy N. Pulvers, Christiane Haffner, Elizabeth P Murchison, Gregory J Hannon, Wieland B. Huttner
miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex.
Development, 135(23) 3911-3921 (2008)
PDF    DOI
---
Yoichi Kosodo, Kazunori Toida, Veronique Dubreuil, Paula Alexandre, Judith Schenk, Emi Kiyokage, Alessio Attardo, Felipe Mora-Bermúdez, Tatsuo Arii, Jon D W Clarke, Wieland B. Huttner
Cytokinesis of neuroepithelial cells can divide their basal process before anaphase.
EMBO J, 27(23) 3151-3163 (2008)
PDF    DOI
---
Jana Karbanová✳︎, Ewa Missol-Kolka✳︎, Ana-Violeta Fonseca, Christoph Lorra, Peggy Janich, Hana Hollerová, József Jászai, Jirí Ehrmann, Zdenek Kolár, Cornelia Liebers, Stefanie Arl, Danuse Subrtová, Daniel Freund, Jaroslav Mokry, Wieland B. Huttner, Denis Corbeil
The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia.
J Histochem Cytochem, 56(11) 977-993 (2008)
PDF    DOI
---
József Jászai, Christine A. Fargeas, Michael Haase, Lilla M. Farkas, Wieland B. Huttner, Denis Corbeil
Robust expression of Prominin-2 all along the adult male reproductive system and urinary bladder.
Histochem Cell Biol, 130(4) 749-759 (2008)
PDF    DOI
---
Lilla M. Farkas, Christiane Haffner, Thomas Giger, Philipp Khaitovich, Katja Nowick, Carmen Birchmeier, Svante Pääbo, Wieland B. Huttner
Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex.
Neuron, 60(1) 40-55 (2008)
PDF    DOI
---
Jennifer L. Fish, Colette Dehay, Henry Kennedy, Wieland B. Huttner
Making bigger brains-the evolution of neural-progenitor-cell division.
J Cell Sci, 121(Pt 17) 2783-2793 (2008)
PDF    DOI
---
Zhenglin Yang, Yali Chen, Concepcion Lillo, Jeremy Chien, Zhengya Yu, Michel Michaelides, Martin Klein, Kim A Howes, Yang Li, Yuuki Kaminoh, Haoyu Chen, Chao Zhao, Yuhong Chen, Youssef Tawfik Al-Sheikh, Goutam Karan, Denis Corbeil, Pascal Escher, Shin Kamaya, Chunmei Li, Samantha Johnson, Jeanne M Frederick, Yu Zhao, Changguan Wang, D Joshua Cameron, Wieland B. Huttner, Daniel F Schorderet, Frances L Munier, Anthony T Moore, David G Birch, Wolfgang Baehr, David M Hunt, David S Williams, Kang Zhang
Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.
J Clin Invest, 118(8) 2908-2916 (2008)
PDF    DOI
---
Sonia Bonilla✳︎, Anita C. Hall✳︎, Luisa Pinto, Alessio Attardo, Magdalena Götz, Wieland B. Huttner, Ernest Arenas
Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors.
Glia, 56(8) 809-820 (2008)
PDF    DOI
---
Hagen B Huttner, Peggy Janich, Martin Köhrmann, József Jászai, Florian Siebzehnrubl, Ingmar Blümcke, Meinolf Suttorp, Manfred Gahr, Daniela Kuhnt, Christopher Nimsky, Dietmar Krex, Gabriele Schackert, Kai Löwenbrück, Heinz Reichmann, Eric Jüttler, Werner Hacke, Peter D Schellinger, Stefan Schwab, Michaela Wilsch-Bräuninger, Anne-Marie Marzesco, Denis Corbeil
The stem cell marker prominin-1/CD133 on membrane particles in human cerebrospinal fluid offers novel approaches for studying central nervous system disease.
Stem Cells, 26(3) 698-705 (2008)
PDF    DOI
---
Jifeng Fei
Studies on the progeny of neuronal progenitors in the developing mouse brain using novel transgenic models of the Tis21 locus
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2008)
---
Jessy Lardon, Denis Corbeil, Wieland B. Huttner, Zhidong Ling, Luc Bouwens
Stem cell marker prominin-1/AC133 is expressed in duct cells of the adult human pancreas.
Pancreas, 36(1) 1-6 (2008)
PDF    DOI
---
Alessio Attardo, Federico Calegari, Wulf Haubensak, Michaela Wilsch-Bräuninger, Wieland B. Huttner
Live imaging at the onset of cortical neurogenesis reveals differential appearance of the neuronal phenotype in apical versus basal progenitor progeny.
PLoS ONE, 3(6) 2388-2388 (2008)
Open Access   PDF    DOI

2007

József Jászai, Christine A. Fargeas, Mareike Florek, Wieland B. Huttner, Denis Corbeil
Focus on molecules: prominin-1 (CD133).
Exp Eye Res, 85(5) 585-586 (2007)
PDF    DOI
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József Jászai, Peggy Janich, Lilla M. Farkas, Christine A. Fargeas, Wieland B. Huttner, Denis Corbeil
Differential expression of Prominin-1 (CD133) and Prominin-2 in major cephalic exocrine glands of adult mice.
Histochem Cell Biol, 128(5) 409-419 (2007)
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Ann Marie Craig, Wieland B. Huttner
Neuronal and glial cell biology.
Curr Opin Neurobiol, 17(5) 505-506 (2007)
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Christine A. Fargeas, Wieland B. Huttner, Denis Corbeil
Nomenclature of prominin-1 (CD133) splice variants - an update.
Tissue Antigens, 69(6) 602-606 (2007)
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Elisabeth Knust, Wieland B. Huttner
Cell polarity from cell division.
Dev Cell, 12(5) 664-666 (2007)
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Mareike Florek✳︎, Nicola Bauer✳︎, Peggy Janich, Michaela Wilsch-Bräuninger, Christine A. Fargeas, Anne-Marie Marzesco, Gerhard Ehninger, Christoph Thiele, Wieland B. Huttner, Denis Corbeil
Prominin-2 is a cholesterol-binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into urine.
Cell Tissue Res, 328(1) 31-47 (2007)
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Veronique Dubreuil, Anne-Marie Marzesco, Denis Corbeil, Wieland B. Huttner, Michaela Wilsch-Bräuninger
Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1.
J Cell Biol, 176(4) 483-495 (2007)
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Jennifer L. Fish
The evolution of neuronal progenitor cell division in mammals: the role of the abnormal spindle-like microcephaly associated (Aspm) protein and epithelial cell polarity
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2007)
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Jeremy N. Pulvers, Judith Schenk, Yoko Arai, Jifeng Fei, Kanako Saito, Wieland B. Huttner
On the origin of neurons.
Genome Biol, 8(7) 311-311 (2007)
Open Access   PDF    DOI
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Michaela Wilsch-Bräuninger#, Wieland B. Huttner#
Neuronale Stamm- und Vorlaeuferzellen
BIOspektrum, 13(4) 369-372 (2007)
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Anna Natalia Grzyb
Characterisation of Y-Box protein 3 (MSY3) in the developing murine central nervous system
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2007)
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2006

Davide De Pietri Tonelli, Federico Calegari, Jifeng Fei, Tadashi Nomura, Noriko Osumi, Carl-Philipp Heisenberg, Wieland B. Huttner
Single-cell detection of microRNAs in developing vertebrate embryos after acute administration of a dual-fluorescence reporter/sensor plasmid.
BioTechniques, 41(6) 727-732 (2006)
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Silvia Cappello, Alessio Attardo, Xunwei Wu, Takuji Iwasato, Shigeyoshi Itohara, Michaela Wilsch-Bräuninger, Hanna M Eilken, Michael A Rieger, Timm T Schroeder, Wieland B. Huttner, Cord Brakebusch, Magdalena Götz
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.
Nat Neurosci, 9(9) 1099-1107 (2006)
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Jennifer L. Fish, Yoichi Kosodo, Wolfgang Enard, Svante Pääbo, Wieland B. Huttner
Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells.
Proc Natl Acad Sci U.S.A., 103(27) 10438-10443 (2006)
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Christian Bökel, Sajith Dass, Michaela Wilsch-Bräuninger, Siegfried Roth
Drosophila Cornichon acts as cargo receptor for ER export of the TGFalpha-like growth factor Gurken.
Development, 133(3) 459-470 (2006)
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Christine A. Fargeas, Ana-Violeta Fonseca, Wieland B. Huttner, Denis Corbeil
Prominin-1 (CD133): from progenitor cells to human diseases
Future Lipidol, 1(2) 213-225 (2006)
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Alessio Attardo
Novel in vivo imaging approaches to study embryonic and adult neurogenesis in the mouse
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2006)
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Veronique Dubreuil, Lilla M. Farkas, Federico Calegari, Yoichi Kosodo, Wieland B. Huttner
Neurogenesis in the central nervous system
In: Cell Signaling and Growth Factors in Development: Vol. 1. (Eds.) Klaus Unsicker, Kerstin Krieglstein,Hoboken, USA,Wiley (2006),229-286 Ch. 7
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2005

Wieland B. Huttner, Yoichi Kosodo
Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous system.
Curr Opin Cell Biol, 17(6) 648-657 (2005)
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Magdalena Götz, Wieland B. Huttner
The cell biology of neurogenesis.
Nat Rev Mol Cell Biol, 6(10) 777-788 (2005)
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Federico Calegari✳︎, Wulf Haubensak✳︎, Christiane Haffner, Wieland B. Huttner
Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain development.
J Neurosci, 25(28) 6533-6538 (2005)
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Anne-Marie Marzesco, Peggy Janich, Michaela Wilsch-Bräuninger, Veronique Dubreuil, Katja Langenfeld, Denis Corbeil, Wieland B. Huttner
Release of extracellular membrane particles carrying the stem cell marker prominin-1 (CD133) from neural progenitors and other epithelial cells.
J Cell Sci, 118(Pt 13) 2849-2858 (2005)
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Audra Lee, Jessica D Kessler, Tracy-Ann Read, Constanze Kaiser, Denis Corbeil, Wieland B. Huttner, Jane E Johnson, Robert J Wechsler-Reya
Isolation of neural stem cells from the postnatal cerebellum.
Nat Neurosci, 8(6) 723-729 (2005)
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Gabriela Kania, Denis Corbeil, Joerg Fuchs, Kirill V Tarasov, Przemyslaw Blyszczuk, Wieland B. Huttner, Kenneth R Boheler, Anna M Wobus
The somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors
Eur J Cell Biol, 84(Supplement 55) 76-76 (2005)
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Denis Corbeil, Christoph Thiele, Wieland B. Huttner
Tyrosine O-Sulfation
In: Current Protocols in Protein Science. (Eds.) Ben M. Dunn, David W. Speicher, Paul T. Wingfield, John E. Coligan,Hoboken, USA,Wiley (2005),1-14 Ch. 14
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Gabriela Kania, Denis Corbeil, Joerg Fuchs, Kirill V Tarasov, Przemyslaw Blyszczuk, Wieland B. Huttner, Kenneth R Boheler, Anna M Wobus
Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors.
Stem Cells, 23(6) 791-804 (2005)
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Frank Buchholz, Federico Calegari, Ralf Kittler, Wieland B. Huttner
RNA interference in postimplantation mouse embryos
In: RNA interference technology: from basic science to drug development. (Eds.) Krishnarao Appasani,Cambridge, UK,Cambridge University Press (2005),207-219 Ch. 15
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Mareike Florek, Michael Haase, Anne-Marie Marzesco, Daniel Freund, Gerhard Ehninger, Wieland B. Huttner, Denis Corbeil
Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer.
Cell Tissue Res, 319(1) 15-26 (2005)
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Anne-Marie Marzesco, Ahmed Zahraoui
Assay of Rab 13 in Regulating Epithelial Tight Junction Assembly
In: GTPases regulating membrane targeting and fusion. (Eds.) William E. Balch Methods in enzymology ; 403.,Amsterdam, Netherlands,Elsevier (2005),182-193 Ch. 15
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2004

Bernd Giebel, Denis Corbeil, Julia Beckmann, Johannes Höhn, Daniel Freund, Kay Giesen, Johannes Fischer, Gesine Kögler, Peter Wernet
Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells.
Blood, 104(8) 2332-2338 (2004)
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Christine A. Fargeas, Angret Joester, Ewa Missol-Kolka, Andrea Hellwig, Wieland B. Huttner, Denis Corbeil
Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis.
J Cell Sci, 117(Pt 18) 4301-4311 (2004)
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Yoichi Kosodo✳︎, Katja Röper✳︎, Wulf Haubensak, Anne-Marie Marzesco, Denis Corbeil, Wieland B. Huttner
Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells.
EMBO J, 23(11) 2314-2324 (2004)
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Flaviana Gentile✳︎, Gaetano Calì✳︎, Chiara Zurzolo, Annunziata Corteggio, Patrizia Rosa, Federico Calegari, Andrea Levi, Roberta Possenti, Claudia Puri, Carlo Tacchetti, Lucio Nitsch
The neuroendocrine protein VGF is sorted into dense-core granules and is secreted apically by polarized rat thyroid epithelial cells.
Exp Cell Res, 295(1) 269-280 (2004)
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Federico Calegari, Anne-Marie Marzesco, Ralf Kittler, Frank Buchholz, Wieland B. Huttner
Tissue-specific RNA interference in post-implantation mouse embryos using directional electroporation and whole embryo culture.
Differentiation, 72(2-3) 92-102 (2004)
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Wulf Haubensak, Alessio Attardo, Winfried Denk, Wieland B. Huttner
Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis.
Proc Natl Acad Sci U.S.A., 101(9) 3196-3201 (2004)
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Denis Corbeil, Wieland B. Huttner
Tyrosine Sulfation
In: Encyclopedia of Biological Chemistry. (Eds.) William Lennarz, M. Lane,Amsterdam, Netherlands,Elsevier (2004),294-297
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2003

Federico Calegari, Wieland B. Huttner
An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis.
J Cell Sci, 116(Pt 24) 4947-4955 (2003)
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Andreas Wodarz, Wieland B. Huttner
Asymmetric cell division during neurogenesis in Drosophila and vertebrates.
Mech Dev, 120(11) 1297-1309 (2003)
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Christine A. Fargeas, Mareike Florek, Wieland B. Huttner, Denis Corbeil
Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins.
J Biol Chem, 278(10) 8586-8596 (2003)
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Andrew W Hunter, Michael Caplow, David L. Coy, William O Hancock, Stefan Diez, Linda Wordeman, Jonathon Howard
The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends.
Mol Cell, 11(2) 445-457 (2003)
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Jan Modregger, Anne A Schmidt, Brigitte Ritter, Wieland B. Huttner, Markus Plomann
Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1.
J Biol Chem, 278(6) 4160-4167 (2003)
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Silvia Coco, Federico Calegari, Elena Pravettoni, Davide Pozzi, Elena Taverna, Patrizia Rosa, Michela Matteoli, Claudia Verderio
Storage and release of ATP from astrocytes in culture.
J Biol Chem, 278(2) 1354-1362 (2003)
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Christine A. Fargeas, Denis Corbeil, Wieland B. Huttner
AC133 antigen, CD133, prominin-1, prominin-2, etc.: prominin family gene products in need of a rational nomenclature.
Stem Cells, 21(4) 506-508 (2003)
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2002

Kazuhisa Kinoshita, Bianca Habermann, Anthony A. Hyman
XMAP215: a key component of the dynamic microtubule cytoskeleton.
Trends Cell Biol, 12(6) 267-273 (2002)
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Amin Rustom, Mark Bajohrs, Christoph Kaether, Patrick Keller, Derek K Toomre, Denis Corbeil, Hans Hermann Gerdes
Selective delivery of secretory cargo in Golgi-derived carriers of nonepithelial cells.
Traffic, 3(4) 279-288 (2002)
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Fedor F. Severin, Anthony A. Hyman
Pheromone induces programmed cell death in S. cerevisiae.
Curr Biol, 12(7) 233-235 (2002)
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Wieland B. Huttner, Anne A Schmidt
Membrane curvature: a case of endofeelin' ...
Trends Cell Biol, 12(4) 155-158 (2002)
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2001

Kazuhisa Kinoshita, Isabelle Arnal, Arshad Desai, David N. Drechsel, Anthony A. Hyman
Reconstitution of physiological microtubule dynamics using purified components.
Science, 294(5545) 1340-1343 (2001)
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Fedor F. Severin, Anthony A. Hyman, Simonetta Piatti
Correct spindle elongation at the metaphase/anaphase transition is an APC-dependent event in budding yeast.
J Cell Biol, 155(5) 711-718 (2001)
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Joanna Rowe, Federico Calegari, Elena Taverna, Renato Longhi, Patrizia Rosa
Syntaxin 1A is delivered to the apical and basolateral domains of epithelial cells: the role of munc-18 proteins.
J Cell Sci, 114(Pt 18) 3323-3332 (2001)
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Wieland B. Huttner
Birth of a new institute--Biopolis Dresden.
Nat Rev Mol Cell Biol, 2(9) 699-703 (2001)
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Martin Klemke, Ralph H. Kehlenbach, Wieland B. Huttner
Two overlapping reading frames in a single exon encode interacting proteins--a novel way of gene usage.
EMBO J, 20(14) 3849-3860 (2001)
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Denis Corbeil, Christine A. Fargeas, Wieland B. Huttner
Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glycoprotein.
Biochem Biophys Res Commun, 285(4) 939-944 (2001)
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Fedor F. Severin, Bianca Habermann, Tim Huffaker, Anthony A. Hyman
Stu2 promotes mitotic spindle elongation in anaphase.
J Cell Biol, 153(2) 435-442 (2001)
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Denis Corbeil, Katja Röper, Christine A. Fargeas, Angret Joester, Wieland B. Huttner
Prominin: a story of cholesterol, plasma membrane protrusions and human pathology.
Traffic, 2(2) 82-91 (2001)
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Jürg Zumbrunn, Kazuhisa Kinoshita, Anthony A. Hyman, Inke S. Näthke
Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation.
Curr Biol, 11(1) 44-49 (2001)
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2000

Martin Klemke, H. Amalia Pasolli, Ralph H. Kehlenbach, Stefan Offermanns, Günter Schultz, Wieland B. Huttner
Characterization of the extra-large G protein alpha-subunit XLalphas. II. Signal transduction properties.
J Biol Chem, 275(43) 33633-33640 (2000)
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Katja Röper, Denis Corbeil, Wieland B. Huttner
Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane.
Nat Cell Biol, 2(9) 582-592 (2000)
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Denis Corbeil✳︎, Katja Röper✳︎, Andrea Hellwig, Manuela Tavian, Sheri Miraglia, Suzanne M. Watt, Paul J. Simmons, Bruno Peault, David W. Buck, Wieland B. Huttner
The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions.
J Biol Chem, 275(8) 5512-5520 (2000)
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Katja Röper✳︎, Denis Corbeil✳︎, Wieland B. Huttner
Distinct Lipid Microdomains within the Apical Plasma Membrane of Polarized Epithelial Cells
In: Protein, Lipid and Membrane Traffic: Pathways and Targeting. (Eds.) Jos A. F. Op den Kamp NATO Science Series: Life Sciences ; 322.,Amsterdam, The Netherlands,IOS Press (2000),73-84 Ch. 10
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Marion A. Maw, Denis Corbeil, Julia Koch, Andrea Hellwig, Jane C. Wilson-Wheeler, Robyn J. Bridges, Govindasamy Kumaramanickavel, Sheila John, Derek Nancarrow, Katja Röper, Anja Weigmann, Wieland B. Huttner, Michael J. Denton
A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration.
Hum Mol Genet, 9(1) 27-34 (2000)
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1999

Erik Nielsen, Fedor F. Severin, Jonathan M Backer, Anthony A. Hyman, Marino Zerial
Rab5 regulates motility of early endosomes on microtubules.
Nat Cell Biol, 1(6) 376-382 (1999)
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Denis Corbeil✳︎, Katja Röper✳︎, Matthew Hannah, Andrea Hellwig, Wieland B. Huttner
Selective localization of the polytopic membrane protein prominin in microvilli of epithelial cells - a combination of apical sorting and retention in plasma membrane protrusions.
J Cell Sci, 112 ( Pt 7) 1023-1033 (1999)
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Matthew Hannah, Anne A Schmidt, Wieland B. Huttner
Synaptic vesicle biogenesis.
Annu Rev Cell Dev Biol, 15 733-798 (1999)
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1998

Christoph Thiele, Wieland B. Huttner
Protein and lipid sorting from the trans-Golgi network to secretory granules-recent developments.
Semin Cell Dev Biol, 9(5) 511-516 (1998)
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Christoph Thiele, Wieland B. Huttner
The disulfide-bonded loop of chromogranins, which is essential for sorting to secretory granules, mediates homodimerization.
J Biol Chem, 273(2) 1223-1231 (1998)
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