Research Groups


Celina Love, Jan Steinkühler, David Thomas Gonzales, Naresh Yandrapalli, Tom Robinson, Rumiana Dimova, T-Y Dora Tang
Reversible pH-Responsive Coacervate Formation in Lipid Vesicles Activates Dormant Enzymatic Reactions.
Angew Chem Int Ed Engl, 59(15) 5950-5957 (2020)


David Thomas Gonzales, T-Y Dora Tang, Christoph Zechner
Moment-based analysis of biochemical networks in a heterogeneous population of communicating cells.
In: 2019 IEEE 58th Conference on Decision and Control (CDC) (2019)(Eds.) Carlos A. Canudas de Wit, Piscataway, N.J., IEEE (2019), 939-944
Hannes Mutschler, Tom Robinson, T-Y Dora Tang, Seraphine Wegner
Special Issue on Bottom-Up Synthetic Biology.
Chembiochem, 20(20) 2533-2534 (2019)
Martina Ugrinic, Andrew deMello, T-Y Dora Tang
Microfluidic Tools for Bottom-Up Synthetic Cellularity
Chem, 5(7) 1727-1742 (2019)
Giorgio Fracasso, Yvonne Körner, David Thomas Gonzales, T-Y Dora Tang
In vitro gene expression and detergent-free reconstitution of active proteorhodopsin in lipid vesicles.
Exp. Biol. Med. (Maywood), 244(4) 314-322 (2019)
Ivan Ivanov, Rafael B. Lira, T-Y Dora Tang, Titus Franzmann, Adam Klosin, Lucas Caire da Silva, Anthony Hyman, Katharina Landfester, Reinhard Lipowsky, Kai Sundmacher, Rumiana Dimova
Directed Growth of Biomimetic Microcompartments.
Adv. Biosys., 3(6) Art. No. 1800314 (2019)


Petra Schwille, Joachim P. Spatz, Katharina Landfester, Eberhard Bodenschatz, Stephan Herminghaus, Victor Sourjik, Tobias Erb, Philippe Bastiaens, Reinhard Lipowsky, Anthony Hyman, Peter Dabrock, Jean-Christophe Baret, Tanja Vidakovic-Koch, Peter Bieling, Rumiana Dimova, Hannes Mutschler, Tom Robinson, T-Y Dora Tang, Seraphine Wegner, Kai Sundmacher
MaxSynBio: Avenues Towards Creating Cells from the Bottom Up.
Angew Chem Int Ed Engl, 57(41) 13382-13392 (2018)
Björn Drobot, Juan M Iglesias-Artola, Kristian Le Vay, Viktoria Mayr, Mrityunjoy Kar, Moritz Kreysing, Hannes Mutschler, T-Y Dora Tang
Compartmentalised RNA catalysis in membrane-free coacervate protocells.
Nat Commun, 9(1) Art. No. 3643 (2018)
T-Y Dora Tang, Dario Cecchi, Giorgio Fracasso, Davide Accardi, Angelique Coutable-Pennarun, Sheref S Mansy, Adam W Perriman, J L Ross Anderson, Stephen Mann
Gene-Mediated Chemical Communication in Synthetic Protocell Communities.
ACS Synth Biol, 7(2) 339-346 (2018)
Martina Ugrinic, Adrian Zambrano, Simon Berger, Stephen Mann, T-Y Dora Tang, Andrew deMello
Microfluidic formation of proteinosomes.
Chem Commun (Camb), 54(3) 287-290 (2018)


Jeffrey R Vieregg, T-Y Dora Tang
Polynucleotides in cellular mimics: Coacervates and lipid vesicles
Curr Opin Colloid Interface Sci, 26 50-57 (2016)


Jennifer M Bulpett, Tim Snow, Benoit Quignon, Charlotte M Beddoes, T-Y D Tang, Stephen Mann, Olga Shebanova, Claire L Pizzey, Nicholas J Terrill, Sean A Davis, Wuge H Briscoe
Hydrophobic nanoparticles promote lamellar to inverted hexagonal transition in phospholipid mesophases.
Soft Matter, 11(45) 8789-8800 (2015)
T-Y Dora Tang, Dirk van Swaay, Andrew deMello, J L Ross Anderson, Stephen Mann
In vitro gene expression within membrane-free coacervate protocells.
Chem Commun (Camb), 51(57) 11429-11432 (2015)
Dirk van Swaay, T-Y Dora Tang, Stephen Mann, Andrew de Mello
Microfluidic Formation of Membrane-Free Aqueous Coacervate Droplets in Water.
Angew Chem Int Ed Engl, 54(29) 8398-8401 (2015)
T-Y Dora Tang, Nicholas J Brooks, Oscar Ces, John M Seddon, Richard H Templer
Structural studies of the lamellar to bicontinuous gyroid cubic (Q(G)(II)) phase transitions under limited hydration conditions.
Soft Matter, 11(10) 1991-1997 (2015)


Mei Li, Xin Huang, T-Y Dora Tang, Stephen Mann
Synthetic cellularity based on non-lipid micro-compartments and protocell models.
Curr Opin Chem Biol, 22 1-11 (2014)
T-Y Dora Tang, C Rohaida Che Hak, Alexander J Thompson, Marina K Kuimova, D S Williams, Adam W Perriman, Stephen Mann
Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model.
Nat Chem, 6(6) 527-533 (2014)
T-Y Dora Tang, Annela M Seddon, Christoph Jeworrek, Roland Winter, Oscar Ces, John M Seddon, Richard H Templer
The effects of pressure and temperature on the energetics and pivotal surface in a monoacylglycerol/water gyroid inverse bicontinuous cubic phase.
Soft Matter, 10(17) 3009-3015 (2014)


T-Y Dora Tang, Massimo Antognozzi, James A. Vicary, Adam W Perriman, Stephen Mann
Small-molecule uptake in membrane-free peptide/nucleotide protocells
Soft Matter, 9 7647-7656 (2013)


T-Y Dora Tang, Nicholas J Brooks, Christoph Jeworrek, Oscar Ces, Nicholas J Terrill, Roland Winter, Richard H Templer, John M Seddon
Hydrostatic pressure effects on the lamellar to gyroid cubic phase transition of monolinolein at limited hydration.
Langmuir, 28(36) 13018-13024 (2012)


Chandrashekhar V. Kulkarni, T-Y Dora Tang, Annela M Seddon, John M Seddon, Oscar Ces, Richard H Templer
Engineering bicontinuous cubic structures at the nanoscale—the role of chain splay
Soft Matter, 6 3191-3194 (2010)