Research Groups


Martina Ugrinic, Andrew deMello, T-Y Dora Tang
Microfluidic Tools for Bottom-Up Synthetic Cellularity
Chem, 5(7) 1727-1742 (2019)
Giorgio Fracasso, Yvonne Körner, David Thomas Gonzales, T-Y Dora Tang
In vitro gene expression and detergent-free reconstitution of active proteorhodopsin in lipid vesicles.
Exp. Biol. Med. (Maywood), 244(4) 314-322 (2019)
Ivan Ivanov, Rafael B. Lira, T-Y Dora Tang, Titus Franzmann, Adam Klosin, Lucas Caire da Silva, Anthony Hyman, Katharina Landfester, Reinhard Lipowsky, Kai Sundmacher, Rumiana Dimova
Directed Growth of Biomimetic Microcompartments
Adv. Biosys., Art. No. doi: 10.1002/adbi.201800314 (2019)


Petra Schwille, Joachim P. Spatz, Katharina Landfester, Eberhard Bodenschatz, Stephan Herminghaus, Victor Sourjik, Tobias Erb, Philippe Bastiaens, Reinhard Lipowsky, Anthony Hyman, Peter Dabrock, Jean-Christophe Baret, Tanja Vidakovic-Koch, Peter Bieling, Rumiana Dimova, Hannes Mutschler, Tom Robinson, T-Y Dora Tang, Seraphine Wegner, Kai Sundmacher
MaxSynBio: Avenues Towards Creating Cells from the Bottom Up.
Angew Chem Int Ed Engl, 57(41) 13382-13392 (2018)
Björn Drobot, Juan M Iglesias-Artola, Kristian Le Vay, Viktoria Mayr, Mrityunjoy Kar, Moritz Kreysing, Hannes Mutschler, T-Y Dora Tang
Compartmentalised RNA catalysis in membrane-free coacervate protocells.
Nat Commun, 9(1) Art. No. 3643 (2018)
T-Y Dora Tang, Dario Cecchi, Giorgio Fracasso, Davide Accardi, Angelique Coutable-Pennarun, Sheref S Mansy, Adam W Perriman, J L Ross Anderson, Stephen Mann
Gene-Mediated Chemical Communication in Synthetic Protocell Communities.
ACS Synth Biol, 7(2) 339-346 (2018)
Martina Ugrinic, Adrian Zambrano, Simon Berger, Stephen Mann, T-Y Dora Tang, Andrew deMello
Microfluidic formation of proteinosomes.
Chem Commun (Camb), 54(3) 287-290 (2018)


Jeffrey R Vieregg, T-Y Dora Tang
Polynucleotides in cellular mimics: Coacervates and lipid vesicles
Curr Opin Colloid Interface Sci, 26 50-57 (2016)


Jennifer M Bulpett, Tim Snow, Benoit Quignon, Charlotte M Beddoes, T-Y D Tang, Stephen Mann, Olga Shebanova, Claire L Pizzey, Nicholas J Terrill, Sean A Davis, Wuge H Briscoe
Hydrophobic nanoparticles promote lamellar to inverted hexagonal transition in phospholipid mesophases.
Soft Matter, 11(45) 8789-8800 (2015)
T-Y Dora Tang, Dirk van Swaay, Andrew deMello, J L Ross Anderson, Stephen Mann
In vitro gene expression within membrane-free coacervate protocells.
Chem Commun (Camb), 51(57) 11429-11432 (2015)
Dirk van Swaay, T-Y Dora Tang, Stephen Mann, Andrew de Mello
Microfluidic Formation of Membrane-Free Aqueous Coacervate Droplets in Water.
Angew Chem Int Ed Engl, 54(29) 8398-8401 (2015)
T-Y Dora Tang, Nicholas J Brooks, Oscar Ces, John M Seddon, Richard H Templer
Structural studies of the lamellar to bicontinuous gyroid cubic (Q(G)(II)) phase transitions under limited hydration conditions.
Soft Matter, 11(10) 1991-1997 (2015)


Mei Li, Xin Huang, T-Y Dora Tang, Stephen Mann
Synthetic cellularity based on non-lipid micro-compartments and protocell models.
Curr Opin Chem Biol, 22 1-11 (2014)
T-Y Dora Tang, C Rohaida Che Hak, Alexander J Thompson, Marina K Kuimova, D S Williams, Adam W Perriman, Stephen Mann
Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model.
Nat Chem, 6(6) 527-533 (2014)
T-Y Dora Tang, Annela M Seddon, Christoph Jeworrek, Roland Winter, Oscar Ces, John M Seddon, Richard H Templer
The effects of pressure and temperature on the energetics and pivotal surface in a monoacylglycerol/water gyroid inverse bicontinuous cubic phase.
Soft Matter, 10(17) 3009-3015 (2014)


T-Y Dora Tang, Massimo Antognozzi, James A. Vicary, Adam W Perriman, Stephen Mann
Small-molecule uptake in membrane-free peptide/nucleotide protocells
Soft Matter, 9 7647-7656 (2013)


T-Y Dora Tang, Nicholas J Brooks, Christoph Jeworrek, Oscar Ces, Nicholas J Terrill, Roland Winter, Richard H Templer, John M Seddon
Hydrostatic pressure effects on the lamellar to gyroid cubic phase transition of monolinolein at limited hydration.
Langmuir, 28(36) 13018-13024 (2012)


Chandrashekhar V. Kulkarni, T-Y Dora Tang, Annela M Seddon, John M Seddon, Oscar Ces, Richard H Templer
Engineering bicontinuous cubic structures at the nanoscale—the role of chain splay
Soft Matter, 6 3191-3194 (2010)