How do cells communicate?

Suzanne Eaton on her research focus

How do cells know which way is up and which down? How do they know where in a tissue they are, and how do they communicate with other cells? Are diseases in some way just a fail of communication of cells?

The 3sat program scobel looked into the mystery cell and also reported on the research performed by Suzanne Eaton at the MPI-CBG - here, 400 scientists from 45 nations ask the same question: How do cells form tissues?