The MODEL SYSTEMS technology area covers all services related to the generation, maintenance and manipulation of model systems. We provide detailed consultation to help you design the best model for addressing your biological question and have a broad range of technologies to create, validate, characterize and preserve experimental systems - from cells in culture to complex animal models. We can also help you with adherence to the safety and ethical regulations related to work with animal models.

Whatever your experimental system is ­– from cells and organoids to model organisms – we have the equipment, experience and know-how to support your experiments.

To test your hypothesis in vivo, we can genetically engineer models with inactivated genes, disease mimicking mutations, or genes tagged with fluorescent or affinity tags for imaging or biochemistry.

If you are using stem cells, we can further reprogram them into various cell types, tissues and organ-like cultures.

We provide custom solutions, training and support with adherence to the safety and ethical regulations related to work with animal models.

We work as a team across multiple facilities – BMS, TCF, GEF, SCOF, DNA, FACS to provide complete solutions through complex cross-facility pipelines.