Services & Facilities

2019

Seungmin Han, Juergen Fink, David J. Jörg, Eunmin Lee, Min Kyu Yum, Lemonia Chatzeli, Sebastian R Merker, Manon Josserand, Teodora Trendafilova, Amanda Andersson-Rolf, Catherine Dabrowska, Hyunki Kim, Ronald Naumann, Ji-Hyun Lee, Nobuo Sasaki, Richard Lester Mort, Onur Basak, Hans Clevers, Daniel E Stange, Anna Philpott, Jong Kyoung Kim, Benjamin D Simons, Bon-Kyoung Koo
Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.
Cell Stem Cell, 25(3) 342-356 (2019)
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João P L Castro, Michelle N Yancoskie, Marta Marchini, Stefanie Belohlavy, Layla Hiramatsu, Marek Kučka, William H Beluch, Ronald Naumann, Isabella Skuplik, John Cobb, Nick H Barton, Campbell Rolian, Yingguang Frank Chan
An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice.
Elife, 8 Art. No. doi: 10.7554/eLife.42014 (2019)
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Branislav Krljanac, Christoph Schubart, Ronald Naumann, Stefan Wirtz, Stephan Culemann, Gerhard Krönke, David Voehringer
RELMα-expressing macrophages protect against fatal lung damage and reduce parasite burden during helminth infection.
Sci Immunol, 4(35) Art. No. eaau3814 (2019)
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Anneke Wilharm, Inga Sandrock, Marie Marotel, Abdi Demera, Ronald Naumann, Thierry Walzer, Immo Prinz
Styk1 is specifically expressed in NK1.1+ lymphocytes including NK, γδ T, and iNKT cells in mice, but is dispensable for their ontogeny and function.
Eur J Immunol, 49(5) 686-693 (2019)
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Shashank Rai, Maryam Arasteh, Matthew Jefferson, Timothy Pearson, Yingxue Wang, Weijiao Zhang, Bertalan Bicsak, Devina Divekar, Penny P Powell, Ronald Naumann, Naiara Beraza, Simon R Carding, Oliver Florey, Ulrike Mayer, Thomas Wileman
The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
Autophagy, 15(4) 599-612 (2019)
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Maarten E Witte, Adrian-Minh Schumacher, Christoph F Mahler, Joerg Bewersdorf, Jonas Lehmitz, Alexander Scheiter, Paula Sánchez, Philip R Williams, Oliver Griesbeck, Ronald Naumann, Thomas Misgeld, Martin Kerschensteiner
Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple Sclerosis.
Neuron, 101(4) 615-624 (2019)
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Elisabeth Zinser, Ronald Naumann, Andreas B Wild, Julia Michalski, Andrea Deinzer, Lena Stich, Christine Kuhnt, Alexander Steinkasserer, Ilka Knippertz
Endogenous Expression of the Human CD83 Attenuates EAE Symptoms in Humanized Transgenic Mice and Increases the Activity of Regulatory T Cells.
Front Immunol, 10 Art. No. 1442 (2019)

2018

Gulce Itir Percin, Jiri Eitler, Andrea Kranz, Jun Fu, Jeffrey W Pollard, Ronald Naumann, Claudia Waskow
CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages.
Nat Commun, 9(1) Art. No. 5279 (2018)
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Inga Sandrock, Annika Reinhardt, Sarina Ravens, Christoph Binz, Anneke Wilharm, Joana Martins, Linda Oberdörfer, Likai Tan, Stefan Lienenklaus, Baojun Zhang, Ronald Naumann, Yuan Zhuang, Andreas Krueger, Reinhold Förster, Immo Prinz
Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells.
J. Exp. Med., 215(12) 3006-3018 (2018)
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Madina Karimova, Oliver Baker, Aylin Camgoz, Ronald Naumann, Frank Buchholz, Konstantinos Anastassiadis
A single reporter mouse line for Vika, Flp, Dre, and Cre-recombination.
Sci Rep, 8(1) Art. No. 14453 (2018)
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Peter Dobrowolski, Melina Fischer, Ronald Naumann
Novel insights into the genetic background of genetically modified mice.
Transgenic Res, 27(3) 265-275 (2018)
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Julia Brenmoehl, Christina Walz, Marion Spitschak, Elisa Wirthgen, Michael Walz, Martina Langhammer, Armin Tuchscherer, Ronald Naumann, Andreas Hoeflich
Partial phenotype conversion and differential trait response to conditions of husbandry in mice.
J Comp Physiol B , 188(3) 527-539 (2018)
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Alina Neunkirchner, Bernhard Kratzer, Cordula Köhler, Ursula Smole, Lukas F Mager, Klaus G Schmetterer, Doris Trapin, Victoria Leb-Reichl, Edward Rosloniec, Ronald Naumann, Lukas Kenner, Beatrice Jahn-Schmid, Barbara Bohle, Rudolf Valenta, Winfried F Pickl
Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice.
EBioMedicine, 31 66-78 (2018)
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Stefano Lazzarano, Marek Kučka, João P L Castro, Ronald Naumann, Paloma Medina, Michael N C Fletcher, Rebecka Wombacher, Joost Gribnau, Tino Hochepied, Marc Van Montagu, Claude Libert, Yingguang Frank Chan
Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells.
Proc Natl Acad Sci U.S.A., 115(14) 3680-3685 (2018)

2017

Katharina S Schneider, Christina J Groß, Roland F Dreier, Benedikt S Saller, Ritu Mishra, Oliver Gorka, Rosalie Heilig, Etienne Meunier, Mathias S Dick, Tamara Ćiković, Jan Sodenkamp, Guillaume Médard, Ronald Naumann, Jurgen Ruland, Bernhard Kuster, Petr Broz, Olaf Groß
The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.
Cell Rep, 21(13) 3846-3859 (2017)
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Sara Carvalhal, Michelle Stevense, Katrin Koehler, Ronald Naumann, Angela Huebner, Rolf Jessberger, Eric R Griffis
ALADIN is required for the production of fertile mouse oocytes.
Mol Biol Cell, 28(19) 2470-2478 (2017)
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Sabine Stopp, Marco Gründl, Marc Fackler, Jonas Malkmus, Marina Leone, Ronald Naumann, Stefan Frantz, Elmar Wolf, Björn von Eyss, Felix B Engel, Stefan Gaubatz
Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development.
Proc Natl Acad Sci U.S.A., 114(30) 8029-8034 (2017)
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Philipp von Hundelshausen, Stijn M Agten, Veit Eckardt, Xavier Blanchet, Martin M Schmitt, Hans Ippel, Carlos Neideck, Kiril Bidzhekov, Julian Leberzammer, Kanin Wichapong, Alexander Faussner, Maik Drechsler, Jochen Grommes, Johanna P van Geffen, He Li, Almudena Ortega-Gomez, Remco T A Megens, Ronald Naumann, Ingrid Dijkgraaf, Gerry A F Nicolaes, Yvonne Döring, Oliver Soehnlein, Esther Lutgens, Johan W M Heemskerk, Rory R Koenen, Kevin H Mayo, Tilman M Hackeng, Christian Weber
Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
Sci Transl Med, 9(384) Art. No. eaah6650 (2017)
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Tatiana Pushkarsky, Evgeny Shilov, Natalya Kruglova, Ronald Naumann, Beda Brichacek, Lucas Jennelle, Dmitri Sviridov, Andrey Kruglov, Sergei Nedospasov, Michael I Bukrinsky
Short Communication: Accumulation of Neutral Lipids in Liver and Aorta of Nef-Transgenic Mice.
AIDS Res Hum Retroviruses, 33(1) 57-60 (2017)

2015

Gesa I Albert, Christoph Schell, Karin M Kirschner, Sebastian Schäfer, Ronald Naumann, Alexandra Müller, Oliver Kretz, Benno Kuropka, Mathias Girbig, Norbert Hübner, Eberhard Krause, Holger Scholz, Tobias B Huber, Klaus-Peter Knobeloch, Christian Freund
The GYF domain protein CD2BP2 is critical for embryogenesis and podocyte function.
J Mol Cell Biol, 7(5) 402-414 (2015)
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Lars Ketscher, Ronny Hannß, David J Morales, Anja Basters, Susana Guerra, Tobias Goldmann, Annika Hausmann, Marco Prinz, Ronald Naumann, Andrew Pekosz, Olaf Utermöhlen, Deborah J Lenschow, Klaus-Peter Knobeloch
Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance.
Proc Natl Acad Sci U.S.A., 112(5) 1577-1582 (2015)

2014

Catherine Diamante Sorbara, Nicolai Wagner, Anne Ladwig, Ivana Nikić, Doron Merkler, Tatjana Kleele, Petar Marinković, Ronald Naumann, Leanne Godinho, Florence M Bareyre, Derron Bishop, Thomas Misgeld, Martin Kerschensteiner
Pervasive Axonal Transport Deficits in Multiple Sclerosis Models.
Neuron, 84(6) 1183-1190 (2014)
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Michael O Breckwoldt, Franz M J Pfister, Peter M Bradley, Petar Marinković, Philip R Williams, Monika S Brill, Barbara Plomer, Anja Schmalz, Daret K St Clair, Ronald Naumann, Oliver Griesbeck, Markus Schwarzländer, Leanne Godinho, Florence M Bareyre, Tobias P Dick, Martin Kerschensteiner, Thomas Misgeld
Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo.
Nat Med, 20(5) 555-560 (2014)
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Hannah Rabenstein, Anna Behrendt, Joachim W Ellwart, Ronald Naumann, Marion Horsch, Johannes Beckers, Reinhard Obst
Differential kinetics of antigen dependency of CD4+ and CD8+ T cells.
J Immunol, 192(8) 3507-3517 (2014)
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Derek Spieler, Maria Kaffe, Franziska Knauf, José Bessa, Juan J Tena, Florian Giesert, Barbara Schormair, Erik Tilch, Hyun-Ok Kate Lee, Marion Horsch, Darina Czamara, Nazanin Karbalai, Christine von Toerne, Melanie Waldenberger, Christian Gieger, Peter Lichtner, Melina Claussnitzer, Ronald Naumann, Bertram Müller-Myhsok, Miguel Torres, Lillian Garrett, Jan Rozman, Martin Klingenspor, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabe de Angelis, Johannes Beckers, Sabine M Hölter, Thomas Meitinger, Stefanie M Hauck, Helmut Laumen, Wolfgang Wurst, Fernando Casares, Jose Luis Gómez-Skarmeta, Juliane Winkelmann
Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon.
Genome Res, 24(4) 592-603 (2014)
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Konstantin Neumann, Mercedes Castiñeiras-Vilariño, Ulrike Höckendorf, Nicole Hannesschläger, Simone Lemeer, Danny Kupka, Svenia Meyermann, Maciej Lech, Hans-Joachim Anders, Bernhard Kuster, Dirk H Busch, Andreas Gewies, Ronald Naumann, Olaf Groß, Jurgen Ruland
Clec12a Is an Inhibitory Receptor for Uric Acid Crystals that Regulates Inflammation in Response to Cell Death.
Immunity, 40(3) 389-399 (2014)
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Andreas Begitt, Mathias Droescher, Thomas Meyer, Christoph D Schmid, Michelle Baker, Filipa Antunes, Markus R Owen, Ronald Naumann, Thomas Decker, Uwe Vinkemeier
STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling.
Nat Immunol, 15(2) 168-176 (2014)
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Tatjana Kleele, Petar Marinković, Philip R Williams, Sina Stern, Emily E Weigand, Peter Engerer, Ronald Naumann, Jana Hartmann, Rosa M Karl, Frank Bradke, Derron Bishop, Jochen Herms, Arthur Konnerth, Martin Kerschensteiner, Leanne Godinho, Thomas Misgeld
An assay to image neuronal microtubule dynamics in mice.
Nat Commun, 5 Art. No. 4827 (2014)

2013

Raymond Behrendt, Tina Schumann, Alexander Gerbaulet, Laura A Nguyen, Nadja Schubert, Dimitra Alexopoulou, Ursula Berka, Stefan Lienenklaus, Katrin Peschke, Kathrin Gibbert, Sabine Wittmann, Dirk Lindemann, Siegfried Weiss, Andreas Dahl, Ronald Naumann, Ulf Dittmer, Baek Kim, Werner Mueller, Thomas Gramberg, Axel Roers
Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.
Cell Rep, 4(4) 689-696 (2013)
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Rashim Pal Singh, Kristin Franke, Joanna Kalucka, Soulafa Mamlouk, Antje Muschter, Agnieszka Gembarska, Tatyana Grinenko, Carsten Willam, Ronald Naumann, Konstantinos Anastassiadis, A Francis Stewart, Stefan Bornstein, Trian Chavakis, Georg Breier, Claudia Waskow, Ben Wielockx
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Blood, 121(26) 5158-5166 (2013)
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Jörg Schönheit, Christiane Kuhl, Marie Luise Gebhardt, Francisco Fernández Klett, Pia Riemke, Marina Scheller, Gang Huang, Ronald Naumann, Achim Leutz, Carol Stocking, Josef Priller, Miguel A Andrade-Navarro, Frank Rosenbauer
PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.
Cell Rep, 3(5) 1617-1628 (2013)
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Natalia Zietara, Marcin Łyszkiewicz, Katrin Witzlau, Ronald Naumann, Robert Hurwitz, Jörg Langemeier, Jens Bohne, Inga Sandrock, Matthias Ballmaier, Siegfried Weiss, Immo Prinz, Andreas Krueger
Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells.
Proc Natl Acad Sci U.S.A., 110(18) 7407-7412 (2013)
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Mariya Rostovskaya, Ronald Naumann, Jun Fu, Mandy Obst, Doris Mueller, A Francis Stewart, Konstantinos Anastassiadis
Transposon mediated BAC transgenesis via pronuclear injection of mouse zygotes.
Genesis, 51(2) 135-141 (2013)

2012

Bjoern Hiller, Martin Achleitner, Silke Glage, Ronald Naumann, Raymond Behrendt, Axel Roers
Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity.
J Exp Med, 209(8) 1419-1426 (2012)
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Jens Haas, Sarina Ravens, Sandra Düber, Inga Sandrock, Linda Oberdörfer, Elham Kashani, Vijaykumar Chennupati, Lisa Föhse, Ronald Naumann, Siegfried Weiss, Andreas Krueger, Reinhold Förster, Immo Prinz
Development of Interleukin-17-Producing γδ T Cells Is Restricted to a Functional Embryonic Wave.
Immunity, 37(1) 48-59 (2012)
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Maria Arantzazu Sanchez-Fernandez, Silvia Sbacchi, Miguel Correa-Tapia, Ronald Naumann, Julia Klemm, Pierre Chambon, Samiya Al-Robaiy, Manfred Blessing, Bernard Hoflack
Transgenic mice for a tamoxifen-induced, conditional expression of the cre recombinase in osteoclasts.
PLoS ONE, 7(5) Art. No. e37592 (2012)
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Ursula Ehmer, Sandra Kalthoff, Bastian Fakundiny, Brigitte Pabst, Nicole Freiberg, Ronald Naumann, Michael P Manns, Christian P Strassburg
Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation.
Hepatology, 55(6) 1912-1921 (2012)

2011

Wei Liu, Min Zi, Ronald Naumann, Susanne Ulm, Jiawei Jin, Domenico M Taglieri, Sukhpal Prehar, Junhong Gui, Hoyee Tsui, Rui-Ping Xiao, Ludwig Neyses, R John Solaro, Yunbo Ke, Elizabeth J Cartwright, Ming Lei, Xin Wang
Pak1 as a Novel Therapeutic Target for Antihypertrophic Treatment in the Heart.
Circulation, 124(24) 2702-2715 (2011)
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Alexander Gerbaulet, Claudia Wickenhauser, Julia Scholten, Katrin Peschke, Sebastian Drube, Hans-Peter Horny, Thomas Kamradt, Ronald Naumann, Werner Müller, Thomas Krieg, Claudia Waskow, Karin Hartmann, Axel Roers
Mast cell hyperplasia, B cell malignancy, and intestinal inflammation in mice with conditional expression of a constitutively active kit.
Blood, 117(6) 2012-2021 (2011)

2010

Julia Elisabeth Pulverer, Ulfert Rand, Stefan Lienenklaus, Daniela Kugel, Natalia Zietara, Georg Kochs, Ronald Naumann, Siegfried Weiss, Peter Staeheli, Hansjörg Hauser, Mario Köster
Temporal and spatial resolution of type I and III interferon responses in vivo.
J Virol, 84(17) 8626-8638 (2010)
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Jeremy N. Pulvers, Jaroslaw Bryk, Jennifer L. Fish, Michaela Wilsch-Bräuninger, Yoko Arai, Dora Schreier, Ronald Naumann, Jussi Helppi, Bianca Habermann, Johannes Vogt, Robert Nitsch, Attila Toth, Wolfgang Enard, Svante Pääbo, Wieland B. Huttner
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline.
Proc Natl Acad Sci U.S.A., 107(38) 16595-16600 (2010)
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Caspar Ohnmacht, Christian Schwartz, Marc Panzer, Isabell Schiedewitz, Ronald Naumann, David Voehringer
Basophils Orchestrate Chronic Allergic Dermatitis and Protective Immunity against Helminths.
Immunity, 33(3) 364-374 (2010)
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Andrea Kranz, Jun Fu, Kristin Duerschke, Stefanie Weidlich, Ronald Naumann, A. Francis Stewart, Konstantinos Anastassiadis
An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase.
Genesis, 48(8) 512-520 (2010)
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Susann Becker, Elke Wandel, Manja Wobus, Rick Schneider, Salah Amasheh, Doreen Sittig, Christiane Kerner, Ronald Naumann, Joerg Hamann, Gabriela Aust
Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions.
PLoS ONE, 5(1) Art. No. e8507 (2010)