Services & Facilities


Juliana Roscito, Katrin Sameith, Martin Pippel, Kees-Jan Francoijs, Sylke Winkler, Andreas Dahl, Georg Papoutsoglou, Gene Myers, Michael Hiller
The genome of the tegu lizard Salvator merianae: combining Illumina, PacBio, and optical mapping data to generate a highly contiguous assembly.
GigaScience, 7(12) Art. No. giy141 (2018)
Samir Vaid, J Gray Camp, Lena Hersemann, Christina Eugster Oegema, Anne-Kristin Heninger, Sylke Winkler, Holger Brandl, Mihail Sarov, Barbara Treutlein, Wieland Huttner, Takashi Namba
A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex.
Development, 145(20) Art. No. dev169276 (2018)
Virag Sharma, Thomas Lehmann, Heiko Stuckas, Liane Funke, Michael Hiller
Loss of RXFP2 and INSL3 genes in Afrotheria shows that testicular descent is the ancestral condition in placental mammals.
PLoS Biol, 16(6) Art. No. e2005293 (2018)
Marta Florio, Michael Heide, Anneline Pinson, Holger Brandl, Mareike Albert, Sylke Winkler, Pauline Wimberger, Wieland B. Huttner, Michael Hiller
Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.
Elife, 7 Art. No. e32332 (2018)
Markus Grohme, Siegfried Schloissnig, Andrei Rozanski, Martin Pippel, George Robert Young, Sylke Winkler, Holger Brandl, Ian Henry, Andreas Dahl, Sean Powell, Michael Hiller, Eugene Myers, Jochen Rink
The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms.
Nature, 554(7690) 56-61 (2018)
Sergej Nowoshilow, Siegfried Schloissnig, Jifeng Fei, Andreas Dahl, Andy W C Pang, Martin Pippel, Sylke Winkler, Alex R Hastie, George Young, Juliana Roscito, Francisco Falcon, Dunja Knapp, Sean Powell, Alfredo Cruz, Han Cao, Bianca Habermann, Michael Hiller, Elly M. Tanaka, Eugene W Myers
The axolotl genome and the evolution of key tissue formation regulators.
Nature, 554(7690) 50-55 (2018)


V Albrecht, C Zweiniger, Vineeth Surendranath, Karl Lang, G Schöfl, Andreas Dahl, Sylke Winkler, V Lange, I Böhme, A H Schmidt
Dual redundant sequencing strategy: Full-length gene characterisation of 1056 novel and confirmatory HLA alleles.
HLA, 90(2) 79-87 (2017)
R Urrego, Sandra Milena Bernal-Ulloa, N A Chavarría, E Herrera-Puerta, Andrea Lucas-Hahn, D Herrmann, Sylke Winkler, Dorit Pache, H Niemann, N Rodriguez-Osorio
Satellite DNA methylation status and expression of selected genes in Bos indicus blastocysts produced in vivo and in vitro.
Zygote, 25(2) 131-140 (2017)
Irene Adrian-Kalchhauser, Ola Svensson, Verena E Kutschera, Magnus Alm Rosenblad, Martin Pippel, Sylke Winkler, Siegfried Schloissnig, Anders Blomberg, Patricia Burkhardt-Holm
The mitochondrial genome sequences of the round goby and the sand goby reveal patterns of recent evolution in gobiid fish.
BMC Genomics, 18(1) Art. No. 177 (2017)
Stephanie Spannl, Alexandra Kumichel, Sarita Hebbar, Katja Kapp, Marcos Gonzalez-Gaitan, Sylke Winkler, Rosana Blawid, Gregor Jessberger, Elisabeth Knust
The Crumbs_C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration.
Biol Open, 6(2) 165-175 (2017)


Nereo Kalebic, Elena Taverna, Stefania Tavano, Fong Kuan Wong, Dana Suchold, Sylke Winkler, Wieland B. Huttner, Mihail Sarov
CRISPR/Cas9-induced disruption of gene expression in mouse embryonic brain and single neural stem cells in vivo.
EMBO Rep, 17(3) 338-348 (2016)
Sandra Milena Bernal-Ulloa, Julia Heinzmann, Doris Herrmann, Klaus-Gerd Hadeler, Patrick Aldag, Sylke Winkler, Dorit Pache, Ulrich Baulain, Andrea Lucas-Hahn, Heiner Niemann
Cyclic AMP Affects Oocyte Maturation and Embryo Development in Prepubertal and Adult Cattle.
PLoS ONE, 11(2) Art. No. e0150264 (2016)


Sylke Winkler, K. Linke, Nicola Gscheidel, M. Meyer, D. Krabel
PCR-based detection of single sequence variants from a natural collection of the non-model tree species European Aspen Populus tremula (L.)
Silvae Genetica, 64(5-6) 259-269 (2015)


Pooja Kumari, Patrick C Gilligan, Shimin Lim, Long Duc Tran, Sylke Winkler, Robin Philp, Karuna Sampath
An essential role for maternal control of Nodal signaling.
Elife, 2 Art. No. e00683 (2013)


Sylke Winkler, Nicola Gscheidel, Michael Brand
Mutant generation in vertebrate model organisms by TILLING.
Methods Mol Biol, 770 475-504 (2011)


Elena Quesada-Hernández, Luca Caneparo, Sylvia Schneider, Sylke Winkler, Michael Liebling, Scott E Fraser, Carl-Philipp Heisenberg
Stereotypical cell division orientation controls neural rod midline formation in zebrafish.
Curr Biol, 20(21) 1966-1972 (2010)


Radoslaw K Ejsmont, Mihail Sarov, Sylke Winkler, Kamil A Lipinski, Pavel Tomancák
A toolkit for high-throughput, cross-species gene engineering in Drosophila.
Nat Methods, 6(6) 435-437 (2009)


John W Hawes, Kevin L Knudtson, Helaman Escobar, George S Grills, Timothy C Hunter, Emily Jackson-Machelski, Heather Lin, David S Needleman, Rashmi Pershad, Glenis J. Wiebe
Evaluation of methods for sequence analysis of highly repetitive DNA templates.
J Biomol Tech, 17(2) 138-144 (2006)


Oliver Bartsch, Stefanie Schmidt, Marion Richter, Susanne Morlot, Eva Seemanová, Glenis J. Wiebe, Sasan Rasi
DNA sequencing of CREBBP demonstrates mutations in 56% of patients with Rubinstein-Taybi syndrome (RSTS) and in another patient with incomplete RSTS.
Hum Genet, 117(5) 485-493 (2005)
Sylke Winkler, Anja Schwabedissen, Dana Backasch, Christian Bökel, Claudia Seidel, Stefanie Bönisch, Maximilian Fürthauer, Antje Kuhrs, Laura Cobreros, Michael Brand, Marcos González-Gaitán
Target-selected mutant screen by TILLING in Drosophila.
Genome Res, 15(5) 718-723 (2005)


Minna H Pöyhönen, Maarit M Peippo, Leena K Valanne, Kirsti E Kuokkanen, Susanna M Koskela, Oliver Bartsch, Sasan Rasi, Glenis J. Wiebe, Marketta Kähkönen, Helena A Kääriäinen
Hypertrichosis, hyperkeratosis, abnormal corpus callosum, mental retardation and dysmorphic features in three unrelated females.
Clin Dysmorphol, 13(2) 85-90 (2004)