Services & Facilities
- Advanced Imaging Facility
- Antibody Facility
- Biomedical Services
- Cell Technologies
- Computer Services
- Electron Microscopy
- Genome Engineering Facility
- International Office
- Library
- Light Microscopy
- Media Technologies and Outreach
- Office of Research Grants
- Office of Technology Transfer
- Organoid and Stem Cell Facility
- Protein Expression Purification and Characterization
- Scientific Computing Facility
- Scientific Infrastructure
- Sequencing and Genotyping
- Technology Development Studio (TDS)
- Transgenic Core
* joined first author
# joined corresponding author
2022
Katharina Holzhüter, Eric R Geertsma
Uniport, Not Proton-Symport, in a Non-Mammalian SLC23 Transporter.
J Mol Biol, 434(2) Art. No. 167393 (2022)
Open Access DOI
Uniport, Not Proton-Symport, in a Non-Mammalian SLC23 Transporter.
J Mol Biol, 434(2) Art. No. 167393 (2022)
Open Access DOI
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Bharath Kumar Raghuraman, Aliona Bogdanova, HongKee Moon, Ignacy Rzagalinski, Eric R Geertsma, Lena Hersemann, Andrej Shevchenko
Median-Based Absolute Quantification of Proteins Using Fully Unlabeled Generic Internal Standard (FUGIS).
J Proteome Res, 21(1) 132-141 (2022)
Open Access DOI
Bharath Kumar Raghuraman, Aliona Bogdanova, HongKee Moon, Ignacy Rzagalinski, Eric R Geertsma, Lena Hersemann, Andrej Shevchenko
Median-Based Absolute Quantification of Proteins Using Fully Unlabeled Generic Internal Standard (FUGIS).
J Proteome Res, 21(1) 132-141 (2022)
Open Access DOI
2020
Juliana G. Roscito, Kaushikaram Subramanian, Ronald Naumann, Mihail Sarov, Anna Shevchenko, Aliona Bogdanova, Thomas Kurth, Leo Foerster, Moritz Kreysing, Michael Hiller
Recapitulating evolutionary divergence in a single cis-regulatory element is sufficient to cause expression changes of the lens gene Tdrd7.
Mol Biol Evol, 38(2) 380-392 (2020)
Open Access DOI
Recapitulating evolutionary divergence in a single cis-regulatory element is sufficient to cause expression changes of the lens gene Tdrd7.
Mol Biol Evol, 38(2) 380-392 (2020)
Open Access DOI
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Elisabeth Nüske, Guendalina Marini, Doris Richter, Weihua Leng, Aliona Bogdanova, Titus Franzmann, Gaia Pigino, Simon Alberti
Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells.
Biol Open, 9(7) Art. No. bio.046391 (2020)
Open Access DOI
Elisabeth Nüske, Guendalina Marini, Doris Richter, Weihua Leng, Aliona Bogdanova, Titus Franzmann, Gaia Pigino, Simon Alberti
Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells.
Biol Open, 9(7) Art. No. bio.046391 (2020)
Open Access DOI
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Katharina Holzhüter, Eric R Geertsma
Functional (un)cooperativity in elevator transport proteins.
Biochem Soc Trans, 48(3) 1047-1055 (2020)
DOI
Katharina Holzhüter, Eric R Geertsma
Functional (un)cooperativity in elevator transport proteins.
Biochem Soc Trans, 48(3) 1047-1055 (2020)
DOI
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Takashi Namba#, Judit Dóczi, Anneline Pinson, Lei Xing, Nereo Kalebic, Michaela Wilsch-Bräuninger, Katherine S. Long, Samir Vaid, Janelle Lauer, Aliona Bogdanova, Barbara Borgonovo, Anna Shevchenko, Patrick Keller, David N. Drechsel, Teymuras V. Kurzchalia, Pauline Wimberger, Christos Chinopoulos, Wieland Huttner#
Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis.
Neuron, 105(5) 867-881 (2020)
DOI
Takashi Namba#, Judit Dóczi, Anneline Pinson, Lei Xing, Nereo Kalebic, Michaela Wilsch-Bräuninger, Katherine S. Long, Samir Vaid, Janelle Lauer, Aliona Bogdanova, Barbara Borgonovo, Anna Shevchenko, Patrick Keller, David N. Drechsel, Teymuras V. Kurzchalia, Pauline Wimberger, Christos Chinopoulos, Wieland Huttner#
Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis.
Neuron, 105(5) 867-881 (2020)
DOI
2019
Regis P. Lemaitre, Aliona Bogdanova, Barbara Borgonovo, Jeffrey Woodruff#, David N. Drechsel#
FlexiBAC: a versatile, open-source baculovirus vector system for protein expression, secretion, and proteolytic processing.
BMC Biotechnol., 19(1) Art. No. 20 (2019)
Open Access DOI
FlexiBAC: a versatile, open-source baculovirus vector system for protein expression, secretion, and proteolytic processing.
BMC Biotechnol., 19(1) Art. No. 20 (2019)
Open Access DOI
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Martina Rauner✳︎, Ulrike Baschant✳︎, Antonella Roetto, Rosa Maria Pellegrino, Sandra Rother, Juliane Salbach-Hirsch, Heike Weidner, Vera Hintze, Graeme Campbell, Andreas Petzold, Regis P. Lemaitre, Ian Henry, Teresita Bellido, Igor Theurl, Sandro Altamura, Silvia Colucci, Martina Muckenthaler, Georg Schett, Davide Komla Ebri, J H Duncan Bassett, Graham R Williams, Uwe Platzbecker, Lorenz C Hofbauer
Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signaling.
Nat Metab, 1(1) 111-124 (2019)
DOI
Martina Rauner✳︎, Ulrike Baschant✳︎, Antonella Roetto, Rosa Maria Pellegrino, Sandra Rother, Juliane Salbach-Hirsch, Heike Weidner, Vera Hintze, Graeme Campbell, Andreas Petzold, Regis P. Lemaitre, Ian Henry, Teresita Bellido, Igor Theurl, Sandro Altamura, Silvia Colucci, Martina Muckenthaler, Georg Schett, Davide Komla Ebri, J H Duncan Bassett, Graham R Williams, Uwe Platzbecker, Lorenz C Hofbauer
Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signaling.
Nat Metab, 1(1) 111-124 (2019)
DOI
2018
Jun Hoe Lee, Kevin M Lewis, Timothy W Moural, Bogdan Kirilenko, Barbara Borgonovo, Gisa Prange, Manfred Koessl, Stefan Huggenberger, ChulHee Kang, Michael Hiller
Molecular parallelism in fast-twitch muscle proteins in echolocating mammals
Sci Adv, 4(9) Art. No. eaat9660 (2018)
Open Access PDF DOI
Molecular parallelism in fast-twitch muscle proteins in echolocating mammals
Sci Adv, 4(9) Art. No. eaat9660 (2018)
Open Access PDF DOI
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Peggy Stolt-Bergner, Christian Benda, Tim Bergbrede, Hüseyin Besir, Patrick H N Celie, Cindy Chang, David N. Drechsel, Ariane Fischer, Arie Geerlof, Barbara Giabbai, Joop van den Heuvel, Georg Huber, Wolfgang Knecht, Anita Lehner, Regis P. Lemaitre, Kristina Nordén, Gwynn Pardee, Ines Racke, Kim Remans, Astrid Sander, Judith Scholz, Magda Stadnik, Paola Storici, Daniel Weinbruch, Isabel Zaror, Linda H L Lua, Sabine Suppmann
Baculovirus-driven protein expression in insect cells: A benchmarking study.
J Struct Biol, 203(2) 71-80 (2018)
DOI
Peggy Stolt-Bergner, Christian Benda, Tim Bergbrede, Hüseyin Besir, Patrick H N Celie, Cindy Chang, David N. Drechsel, Ariane Fischer, Arie Geerlof, Barbara Giabbai, Joop van den Heuvel, Georg Huber, Wolfgang Knecht, Anita Lehner, Regis P. Lemaitre, Kristina Nordén, Gwynn Pardee, Ines Racke, Kim Remans, Astrid Sander, Judith Scholz, Magda Stadnik, Paola Storici, Daniel Weinbruch, Isabel Zaror, Linda H L Lua, Sabine Suppmann
Baculovirus-driven protein expression in insect cells: A benchmarking study.
J Struct Biol, 203(2) 71-80 (2018)
DOI
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Mukesh Kumar, Shai Joseph, Martina Augsburg, Aliona Bogdanova, David N. Drechsel, Nadine Vastenhouw, Frank Buchholz, Marc Gentzel, Andrej Shevchenko
MS Western, a Method of Multiplexed Absolute Protein Quantification is a Practical Alternative to Western Blotting.
Mol Cell Proteomics, 17(2) 384-396 (2018)
Open Access DOI
Mukesh Kumar, Shai Joseph, Martina Augsburg, Aliona Bogdanova, David N. Drechsel, Nadine Vastenhouw, Frank Buchholz, Marc Gentzel, Andrej Shevchenko
MS Western, a Method of Multiplexed Absolute Protein Quantification is a Practical Alternative to Western Blotting.
Mol Cell Proteomics, 17(2) 384-396 (2018)
Open Access DOI
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Catarina Oliveira, Regis P. Lemaitre, Prayag Murawala, Akira Tazaki, David N. Drechsel, Elly M. Tanaka
Pseudotyped baculovirus is an effective gene expression tool for studying molecular function during axolotl limb regeneration.
Dev Biol, 433(2) 262-275 (2018)
DOI
Catarina Oliveira, Regis P. Lemaitre, Prayag Murawala, Akira Tazaki, David N. Drechsel, Elly M. Tanaka
Pseudotyped baculovirus is an effective gene expression tool for studying molecular function during axolotl limb regeneration.
Dev Biol, 433(2) 262-275 (2018)
DOI
2017
Jifeng Fei, Maritta Schuez, Dunja Knapp, Yuka Taniguchi, David N. Drechsel, Elly M. Tanaka
Efficient gene knockin in axolotl and its use to test the role of satellite cells in limb regeneration.
Proc Natl Acad Sci U.S.A., 114(47) 12501-12506 (2017)
DOI
Efficient gene knockin in axolotl and its use to test the role of satellite cells in limb regeneration.
Proc Natl Acad Sci U.S.A., 114(47) 12501-12506 (2017)
DOI
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Tobias Boothe, Lennart Hilbert, Michael Heide, Lea Berninger, Wieland B. Huttner, Vasily Zaburdaev, Nadine Vastenhouw, Eugene W Myers, David N. Drechsel, Jochen Rink
A tunable refractive index matching medium for live imaging cells, tissues and model organisms.
Elife, 6 Art. No. e27240 (2017)
Open Access DOI
Tobias Boothe, Lennart Hilbert, Michael Heide, Lea Berninger, Wieland B. Huttner, Vasily Zaburdaev, Nadine Vastenhouw, Eugene W Myers, David N. Drechsel, Jochen Rink
A tunable refractive index matching medium for live imaging cells, tissues and model organisms.
Elife, 6 Art. No. e27240 (2017)
Open Access DOI
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Jovan Mircetic, Iris Steinebrunner, Li Ding, Jifeng Fei, Aliona Bogdanova, David N. Drechsel, Frank Buchholz
Purified Cas9 Fusion Proteins for Advanced Genome Manipulation.
Small Methods, 1(4) Art. No. 1600052 (2017)
DOI
Jovan Mircetic, Iris Steinebrunner, Li Ding, Jifeng Fei, Aliona Bogdanova, David N. Drechsel, Frank Buchholz
Purified Cas9 Fusion Proteins for Advanced Genome Manipulation.
Small Methods, 1(4) Art. No. 1600052 (2017)
DOI
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Ines Wagner✳︎, Heng Wang, Philipp M Weissert, Werner L Straube✳︎, Anna Shevchenko, Marc Gentzel, Goncalo Brito, Akira Tazaki, Catarina Oliveira, Takuji Sugiura, Andrej Shevchenko, András Simon, David N. Drechsel, Elly M. Tanaka
Serum Proteases Potentiate BMP-Induced Cell Cycle Re-entry of Dedifferentiating Muscle Cells during Newt Limb Regeneration.
Dev Cell, 40(6) 608-617 (2017)
DOI
Ines Wagner✳︎, Heng Wang, Philipp M Weissert, Werner L Straube✳︎, Anna Shevchenko, Marc Gentzel, Goncalo Brito, Akira Tazaki, Catarina Oliveira, Takuji Sugiura, Andrej Shevchenko, András Simon, David N. Drechsel, Elly M. Tanaka
Serum Proteases Potentiate BMP-Induced Cell Cycle Re-entry of Dedifferentiating Muscle Cells during Newt Limb Regeneration.
Dev Cell, 40(6) 608-617 (2017)
DOI
2016
Elvan Boke, Martine Ruer, Martin Wühr, Margaret Coughlin, Regis P. Lemaitre, Steven Gygi, Simon Alberti, David N. Drechsel, Anthony Hyman, Timothy J. Mitchison
Amyloid-like Self-Assembly of a Cellular Compartment.
Cell, 166(3) 637-650 (2016)
DOI
Amyloid-like Self-Assembly of a Cellular Compartment.
Cell, 166(3) 637-650 (2016)
DOI
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Eugeniu Nacu, Elena Gromberg, Catarina Oliveira, David N. Drechsel, Elly M. Tanaka
FGF8 and SHH substitute for anterior-posterior tissue interactions to induce limb regeneration.
Nature, 533(7603) 407-410 (2016)
DOI
Eugeniu Nacu, Elena Gromberg, Catarina Oliveira, David N. Drechsel, Elly M. Tanaka
FGF8 and SHH substitute for anterior-posterior tissue interactions to induce limb regeneration.
Nature, 533(7603) 407-410 (2016)
DOI
2015
Anneke Hibbel, Aliona Bogdanova, Mohammed Mahamdeh, Anita Jannasch, Marko Storch, Erik Schäffer, Dimitris Liakopoulos, Jonathon Howard
Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe.
Elife, 4 Art. No. e10542 (2015)
Open Access PDF DOI
Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe.
Elife, 4 Art. No. e10542 (2015)
Open Access PDF DOI
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Avinash Patel, Hyun-Ok Kate Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus Franzmann, Andrei Pozniakovski, Ina Poser, Nicola Maghelli, Loic Royer, Martin Weigert, Eugene W Myers, Stephan W. Grill, David N. Drechsel, Anthony Hyman, Simon Alberti
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Cell, 162(5) 1066-1077 (2015)
DOI
Avinash Patel, Hyun-Ok Kate Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus Franzmann, Andrei Pozniakovski, Ina Poser, Nicola Maghelli, Loic Royer, Martin Weigert, Eugene W Myers, Stephan W. Grill, David N. Drechsel, Anthony Hyman, Simon Alberti
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Cell, 162(5) 1066-1077 (2015)
DOI
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Robert Wieduwild, Swati Krishnan, Karolina Chwalek, Annett Boden, Matthias Nowak, David N. Drechsel, Carsten Werner, Yixin Zhang
Noncovalent hydrogel beads as microcarriers for cell culture.
Angew Chem Int Ed Engl, 54(13) 3962-3966 (2015)
DOI
Robert Wieduwild, Swati Krishnan, Karolina Chwalek, Annett Boden, Matthias Nowak, David N. Drechsel, Carsten Werner, Yixin Zhang
Noncovalent hydrogel beads as microcarriers for cell culture.
Angew Chem Int Ed Engl, 54(13) 3962-3966 (2015)
DOI
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Juha M. Torkko, María E Primo, Ronald Dirkx, Anne Friedrich, Antje Viehrig, Elisa Vergari, Barbara Borgonovo, Anke Sönmez, Carolin Wegbrod, Martina Lachnit, Carla Münster, Mauricio P Sica, Mario R Ermácora, Michele Solimena
Stability of proICA512/IA-2 and Its Targeting to Insulin Secretory Granules Require β4-Sheet-Mediated Dimerization of Its Ectodomain in the Endoplasmic Reticulum.
Mol Cell Biol, 35(6) 914-927 (2015)
DOI
Juha M. Torkko, María E Primo, Ronald Dirkx, Anne Friedrich, Antje Viehrig, Elisa Vergari, Barbara Borgonovo, Anke Sönmez, Carolin Wegbrod, Martina Lachnit, Carla Münster, Mauricio P Sica, Mario R Ermácora, Michele Solimena
Stability of proICA512/IA-2 and Its Targeting to Insulin Secretory Granules Require β4-Sheet-Mediated Dimerization of Its Ectodomain in the Endoplasmic Reticulum.
Mol Cell Biol, 35(6) 914-927 (2015)
DOI
2012
Per Widlund, Marija Podolski, Simone Reber, Joshua Alper, Marko Storch, Anthony Hyman, Jonathon Howard, David N. Drechsel
One-step purification of assembly-competent tubulin from diverse eukaryotic sources.
Mol Biol Cell, 23(22) 4393-4401 (2012)
DOI
One-step purification of assembly-competent tubulin from diverse eukaryotic sources.
Mol Biol Cell, 23(22) 4393-4401 (2012)
DOI
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Aurelie Tomczak, Jana Sontheimer, David N. Drechsel, Rainer Hausdorf, Marc Gentzel, Andrej Shevchenko, Stefanie Eichler, Karim Fahmy, Frank Buchholz, Maria Teresa Pisabarro
3D profile-based approach to proteome-wide discovery of novel human chemokines
PLoS ONE, 7(5) Art. No. e36151 (2012)
Open Access DOI
Aurelie Tomczak, Jana Sontheimer, David N. Drechsel, Rainer Hausdorf, Marc Gentzel, Andrej Shevchenko, Stefanie Eichler, Karim Fahmy, Frank Buchholz, Maria Teresa Pisabarro
3D profile-based approach to proteome-wide discovery of novel human chemokines
PLoS ONE, 7(5) Art. No. e36151 (2012)
Open Access DOI
2011
Uenal Coskun, Michal Grzybek, Kai Simons, David N. Drechsel
Regulation of human EGF receptor by lipids
Proc Natl Acad Sci U.S.A., 108(22) 9044-9048 (2011)
PDF
Regulation of human EGF receptor by lipids
Proc Natl Acad Sci U.S.A., 108(22) 9044-9048 (2011)
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Christopher Gell, Claire Friel, Barbara Borgonovo, David N. Drechsel, Anthony A. Hyman, Jonathon Howard
Purification of tubulin from porcine brain.
Methods Mol Biol, 777 15-28 (2011)
PDF DOI
Christopher Gell, Claire Friel, Barbara Borgonovo, David N. Drechsel, Anthony A. Hyman, Jonathon Howard
Purification of tubulin from porcine brain.
Methods Mol Biol, 777 15-28 (2011)
PDF DOI
2010
Lars Renner, Tilo Pompe, Regis P. Lemaitre, David N. Drechsel, Carsten Werner
Controlled enhancement of transmembrane enzyme activity in polymer cushioned supported bilayer membranes
Soft Matter, 6 5382-5389 (2010)
PDF DOI
Controlled enhancement of transmembrane enzyme activity in polymer cushioned supported bilayer membranes
Soft Matter, 6 5382-5389 (2010)
PDF DOI
2009
Takeshi Ohya, Marta Miaczynska, Uenal Coskun, Barbara Lommer, Anja Runge, David N. Drechsel, Yannis Kalaidzidis, Marino Zerial
Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.
Nature, 459(7250) 1091-1097 (2009)
PDF DOI
Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.
Nature, 459(7250) 1091-1097 (2009)
PDF DOI
2007
Sara Lööf, Werner L. Straube, David N. Drechsel, Elly M. Tanaka, András Simon
Plasticity of mammalian myotubes upon stimulation with a thrombin-activated serum factor.
Cell Cycle, 6(9) 1096-1101 (2007)
PDF
Plasticity of mammalian myotubes upon stimulation with a thrombin-activated serum factor.
Cell Cycle, 6(9) 1096-1101 (2007)
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Nicola Bauer
New insights into the plasma membrane dynamics of rare stem cells by studying the prominin molecule
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2007)
Nicola Bauer
New insights into the plasma membrane dynamics of rare stem cells by studying the prominin molecule
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2007)
2006
Hassan Mziaut, Mirko Trajkovski, Stephan Kersting, Armin Ehninger, Anke Altkrüger, Regis P. Lemaitre, Darja Schmidt, Hans-Detlev Saeger, Myung-Shik Lee, David N. Drechsel, Stefan Müller, Michele Solimena
Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5.
Nat Cell Biol, 8(5) 435-445 (2006)
PDF DOI
Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5.
Nat Cell Biol, 8(5) 435-445 (2006)
PDF DOI
2004
Gideon Lansbergen, Yulia Komarova, Mauro Modesti, Claire Wyman, Casper C Hoogenraad, Holly V Goodson, Regis P. Lemaitre, David N. Drechsel, Erik van Munster, Theodorus W J Gadella, Frank Grosveld, Niels Galjart, Gary G Borisy, Anna Akhmanova
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization.
J Cell Biol, 166(7) 1003-1014 (2004)
PDF DOI
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization.
J Cell Biol, 166(7) 1003-1014 (2004)
PDF DOI
2002
Nnennaya Kanu, Yutaka Imokawa, David N. Drechsel, R Anthony Williamson, Christopher R Birkett, Christopher J Bostock, Jeremy P. Brockes
Transfer of scrapie prion infectivity by cell contact in culture.
Curr Biol, 12(7) 523-530 (2002)
PDF
Transfer of scrapie prion infectivity by cell contact in culture.
Curr Biol, 12(7) 523-530 (2002)
1999
Elly M. Tanaka, David N. Drechsel, Jeremy P. Brockes
Thrombin regulates S-phase re-entry by cultured newt myotubes.
Curr Biol, 9(15) 792-799 (1999)
PDF
Thrombin regulates S-phase re-entry by cultured newt myotubes.
Curr Biol, 9(15) 792-799 (1999)