Services & Facilities

Mouse genome editing by pronuclear injection in collaboration with Transgenic Core Facility

Knock-Out/Pointmutation Mouse

  • Guide RNA design and synthesis
  • Pronuclear Injection by TCF-Pointmutation: HDR template
  • TOPO- cloning
  • Sequencing including sequence validation

Knock-In Mouse

  • Guide RNA design and synthesis
  • Pronuclear Injection by TCF
  • HDR construct cloning
  • TOPO- cloning
  • Sequencing including sequence validation