Research Groups

The Alberti Lab

General Contact Information

Max Planck Institute
of Molecular Cell Biology and Genetics
- Alberti -

Pfotenhauerstr. 108
01307 Dresden

Phone +49 351 210 2663
Fax +49 351 210 1209

Current Lab Members

Name Position Email Phone
Alberti, Simon Group Leader
Eßlinger, Anne Predoc +49 351 210-2453
Franzmann, Titus Postdoc +49 351 210-1245
Iserman, Christiane Predoc +49 351 210-2714
Kopach, Andrii Predoc +49 351 210-2915
Maharana, Shovamayee Postdoc +49 351 210-2778
Richter, Doris TA +49 351 210-2998
Trovesi, Elena Head of Administration +49 351 210-1043
Trussina, Irmela Predoc +49 351 210-2577

Christine Desroches Altamirano
PhD student

Christine is interested in relating the phase separation of stress granule proteins to their function in the cellular stress response. She is also interested in how evolution fine-tunes the phase behaviour of these proteins to regulate protein function.

Jordina Guillén Boixet

Jordina is studying how different physical-chemical parameters affect the dynamics of RNP granules, using mammalian cells as a model system. She is particularly interested in how variations in those parameters relate to neurodegenerative disorders.

Andrii Kopach
PhD student

Andrii is working on in vitro reconstitution of stress granules from minimal components.

Irmela Trussina
PhD student

Irmela is studying mechanisms that regulate phase behaviour of human prion-like RNA-binding proteins. She is especially interested in RNA helicases and their possible functions in regulating phase separation and the maintenance of the liquid-like state.

Titus Franzmann

Titus is interested in understanding the molecular and physical mechanisms that enable cells to adapt to and recover from environmental variations. He links the folding state of the cytoplasm and its physical property changes to the fitness of cells. Combing biochemistry and biophysics with cell biology he aims to describe the adaptive mechanisms on the scales ranging from the protein to the organism level.

Shovamajee Maharana

Shova is interested in environmental stresses that cause a rapid reprogramming of the cellular biochemistry from house-keeping to cyto-protective functions. This reprogramming often affects RNP granule organization and it is also associated with age-related neurodegeneration diseases. She is particularly interested in studying the role of RNA in shaping the spatio-temporal distribution of RNP granules during stress and in disease conditions.

Anne Eßlinger
PhD student

Anne is interested in cytoplasmic material property changes in response to environmental stress in yeast. She is using various biophysical approaches as well as genetic perturbations to study how these changes are regulated.

Christiane Iserman
PhD student

Chrissy is studying a protein that forms assemblies through stress-induced liquid-liquid phase separation. Apart from being interested in the mechanism and function of stress sensing, she also has a wider look at the evolutionary adaptations in organisms that live in distinct ecological niches.

Doris Richter
Technician and lab manager

As the lab manager Doris is interested in all sorts of things and she is trying to keep things running smoothly in the lab. She is also doing most of the cloning in the lab.


William Hirst

William investigated how nutritional cues modulate the folding and holding functions of chaperones.

Gayathrie Kulasegaran
Master student

Gayathrie purified a metabolic enzyme from E. coli and reconstituted its filament-forming abilities in vitro.

Daniel Mateju
PhD student and postdoc

Daniel was studying the interaction of RNP granules with misfolded proteins and the role of the protein quality control machinery in this process.

Elisabeth Nueske
PhD student and postdoc

Elli was investigating a set of proteins that form reversible assemblies upon nutritional and environmental stress.

Ivana Petrovska
Postdoctoral fellow

Ivana investigated a metabolic enzyme that reversibly forms filaments upon nutritional stress.

Sonja Kroschwald
PhD student and postdoc

Sonja studied how RNP granules such as P bodies and stress granules form in budding yeast.

Liliana Malinovska
PhD student and postdoc

Lili was interested in understanding how Dictyostelium discoideum is controlling its highly misfolding-prone Q/N-rich proteome.

Matthias Munder
PhD student and postdoc

Matthias was studying dormancy in different eukaryotic model organisms.

Sandra Palm
Bachelor student

Sandra investigated the ability of computationally predicted prion-like sequences from Dictyostelium to form amyloids and prions. 

Alessandro Rinaldi
Master student

Alessandro investigated a new system for studying protein-protein interactions in cells based on a viral capsid protein.