Microscope development

People Involved

  • Nicola Maghelli
  • Loic Royer
  • Martin Weigert

Project Description

We are developing a multi-view, multi-illumination selective plane microscope. We aim at imaging C. elegans and D. melanogaster embryogenesis at unprecedented spatial and temporal resolution. Our microscope will use advanced optics, including a custom designed line of immersion objectives, in combination with high performance software which will allow for controlling the microscope hardware.

Imaging of a developing C. elegans embryo, labelled with histone-GFP

We developed both the optics and the mechanics for our custom objective.
For the design of our microscope, we used extensively 3D mechanical CAD and optical simulation programs.