Research Groups

* joined first author # joined corresponding author

2021

Rita Mateus#, Jana Fuhrmann, Natalie Dye#
Growth across scales: Dynamic signaling impacts tissue size and shape.
Curr Opin Cell Biol, 73 50-57 (2021)
Open Access   DOI
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Stephanie Spannl, Tomasz Buhl, Ioannis Nellas, Salma A Zeidan, K Venkatesan Iyer, Helena Khaliullina, Carsten Schultz, André Nadler, Natalie Dye, Suzanne Eaton
Glycolysis regulates Hedgehog signalling via the plasma membrane potential : Erratum ; Correction to EMBO J. 39 (2020) 21: e101767
EMBO J, 40(7) Art. No. 107925 (2021)
DOI
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Natalie Dye✳︎#, Marko Popovic✳︎, K Venkatesan Iyer, Jana Fuhrmann, Romina Piscitello-Gómez, Suzanne Eaton, Frank Jülicher#
Self-organized patterning of cell morphology via mechanosensitive feedback.
Elife, 10 Art. No. e57964 (2021)
Open Access   DOI
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K Venkatesan Iyer#, Anna Taubenberger, Salma A Zeidan, Natalie Dye, Suzanne Eaton, Frank Jülicher#
Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues.
Nat Commun, 12(1) Art. No. 1756 (2021)
Open Access   DOI
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Marko Popović✳︎#, Valentin Druelle✳︎, Natalie Dye, Frank Jülicher, Matthieu Wyart#
Inferring the flow properties of epithelial tissues from their geometry.
New J Phys, 23 Art. No. 033004 (2021)
Open Access   DOI

2020

Ivona Mateska, Kareena Nanda, Natalie Dye, Vasileia Ismini Alexaki, Suzanne Eaton
Range of SHH signaling in adrenal gland is limited by membrane contact to cells with primary cilia.
J Cell Biol, 219(12) Art. No. e201910087 (2020)
DOI
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Stephanie Spannl#, Tomasz Buhl, Ioannis Nellas, Salma A Zeidan, K Venkatesan Iyer, Helena Khaliullina, Carsten Schultz, André Nadler, Natalie Dye#, Suzanne Eaton
Glycolysis regulates Hedgehog signalling via the plasma membrane potential.
EMBO J, 39(21) Art. No. e101767 (2020)
Open Access   DOI

2019

Natalie Dye, Ali Mahmoud, K. Venkatesan Iyer, Ivona Mateska#, Suhrid Ghosh, Ioannis Nellas, Romina Piscitello-Gómez#, Salma Ahmed Zeidan, Jana Fuhrmann, Allison Lewis, Abhijeet Krishna
Suzanne Eaton (1959-2019) Obituary
Dev Cell, 50(6) 680-682 (2019)
DOI
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Natalie Dye, Ali Mahmoud, K. Venkatesan Iyer, Ivona Mateska#, Suhrid Ghosh, Ioannis Nellas, Romina Piscitello-Gómez#, Salma Ahmed Zeidan, Jana Fuhrmann, Allison Lewis, Abhijeet Krishna
Suzanne Eaton (1959-2019) - Obituary
Cell, 179(1) 18-20 (2019)
DOI
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Valentina Greco, Suhrid Ghosh
Suzanne Eaton: 1959-2019.
Nat Cell Biol, 21(9) 1053-1054 (2019)
DOI
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Anna Bajur, K Venkatesan Iyer, Elisabeth Knust
Cytocortex-dependent dynamics of Drosophila Crumbs controls junctional stability and tension during germ band retraction.
J Cell Sci, 132(15) Art. No. jcs228338 (2019)
DOI
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Suhrid Ghosh
Tribute to Suzanne Eaton, from her lab members.
Nature, 572(7768) 178-178 (2019)
DOI
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K Venkatesan Iyer#, Romina Piscitello-Gómez, Joris Paijmans, Frank Jülicher#, Suzanne Eaton#
Epithelial Viscoelasticity Is Regulated by Mechanosensitive E-cadherin Turnover.
Curr Biol, 29(4) 578-591 (2019)
DOI
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Elodie Prince, Benjamin Kroeger, Dragan Gligorov, Clive Wilson, Suzanne Eaton, François Karch, Marko Brankatschk, Robert K Maeda
Rab-mediated trafficking in the secondary cells of Drosophila male accessory glands and its role in fecundity.
Traffic, 20(2) 137-151 (2019)
Open Access   DOI

2018

Liyuan Sui, Silvanus Alt, Martin Weigert, Natalie Dye, Suzanne Eaton, Florian Jug, Eugene W Myers, Frank Jülicher, Guillaume Salbreux, Christian Dahmann
Differential lateral and basal tension drive folding of Drosophila wing discs through two distinct mechanisms.
Nat Commun, 9(1) Art. No. 4620 (2018)
Open Access   DOI
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Marko Brankatschk#, Theresia Gutmann, Oskar Knittelfelder, Alessandra Palladini, Elodie Prince, Michal Grzybek, Beate Brankatschk, Andrej Shevchenko, Ünal Coskun, Suzanne Eaton#
A Temperature-Dependent Switch in Feeding Preference Improves Drosophila Development and Survival in the Cold.
Dev Cell, 46(6) 781-793 (2018)
DOI

2017

Natalie Dye, Marko Popović, Stephanie Spannl, Raphael Etournay, Dagmar Kainmüller, Suhrid Ghosh, Eugene W Myers, Frank Jülicher, Suzanne Eaton
Cell dynamics underlying oriented growth of the Drosophila wing imaginal disc.
Development, 144(23) 4406-4421 (2017)
DOI
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Corinna Blasse, Stephan Saalfeld, Raphael Etournay, Andreas Sagner, Suzanne Eaton, Eugene W Myers
PreMosa: extracting 2D surfaces from 3D microscopy mosaics.
Bioinformatics, 33(16) 2563-2569 (2017)
DOI
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Frank Jülicher, Suzanne Eaton
Emergence of tissue shape changes from collective cell behaviours.
Semin Cell Dev Biol, 67 103-112 (2017)
DOI
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Matthias Merkel, Raphael Etournay, Marko Popović, Guillaume Salbreux, Suzanne Eaton, Frank Jülicher
Triangles bridge the scales: Quantifying cellular contributions to tissue deformation.
Phys Rev E, 95(3) Art. No. 032401 (2017)
DOI
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Marko Popović, Amitabha Nandi, Matthias Merkel, Raphael Etournay, Suzanne Eaton, Frank Jülicher, Guillaume Salbreux
Active dynamics of tissue shear flow
New J Phys, 19(3) Art. No. 033006 (2017)
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2016

Sara Caviglia, Marko Brankatschk, Elisabeth Fischer, Suzanne Eaton, Stefan Luschnig
Staccato/Unc-13-4 controls secretory lysosome-mediated lumen fusion during epithelial tube anastomosis.
Nat Cell Biol, 18(7) 727-739 (2016)
DOI
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Raphael Etournay, Matthias Merkel, Marko Popović, Holger Brandl, Natalie Dye, Benoit Aigouy, Guillaume Salbreux, Suzanne Eaton, Frank Jülicher
TissueMiner: a multiscale analysis toolkit to quantify how cellular processes create tissue dynamics.
Elife, 5 Art. No. e14334 (2016)
Open Access   PDF    DOI
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Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R Shcherbata
Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet.
Genetics, 202(3) 1167-1183 (2016)
DOI
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Benoit Aigouy, Daiki Umetsu, Suzanne Eaton
Segmentation and Quantitative Analysis of Epithelial Tissues.
Methods Mol Biol, 1478 227-239 (2016)
DOI
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Mesut Bilgin, Petra Born, Filomena Fezza, Michael Heimes, Nicolina Mastrangelo, Nicolai Wagner, Carsten Schultz, Mauro Maccarrone, Suzanne Eaton, André Nadler, Matthias Wilm, Andrej Shevchenko
Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS.
Sci Rep, 6 Art. No. 27920 (2016)
Open Access   PDF    DOI

2015

Stephanie Spannl
Identification of the protein Ecdysoneless as a regulator of Hedgehog signaling
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2015)
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Barbara Sorce, Carlos Escobedo, Yusuke Toyoda, Martin P Stewart, Cedric J Cattin, Richard Newton, Indranil Banerjee, Alexander Stettler, Botond Roska, Suzanne Eaton, Anthony Hyman, Andreas Hierlemann, Daniel J. Müller
Mitotic cells contract actomyosin cortex and generate pressure to round against or escape epithelial confinement.
Nat Commun, 6 Art. No. 8872 (2015)
Open Access   PDF    DOI
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Oksana Lavrynenko, Jonathan Rodenfels, Maria Carvalho, Natalie Dye, Rene Lafont, Suzanne Eaton, Andrej Shevchenko
The ecdysteroidome of Drosophila: influence of diet and development.
Development, 142(21) 3758-3768 (2015)
DOI
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Sebastian Dunst, Tom Kazimiers, Felix von Zadow, Helena Jambor, Andreas Sagner, Beate Brankatschk, Ali Mahmoud, Stephanie Spannl, Pavel Tomancak#, Suzanne Eaton#, Marko Brankatschk#
Endogenously Tagged Rab Proteins: A Resource to Study Membrane Trafficking in Drosophila.
Dev Cell, 33(3) 351-365 (2015)
DOI
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Bomsoo Cho, Gandhy Pierre-Louis, Andreas Sagner, Suzanne Eaton, Jeffrey D Axelrod
Clustering and negative feedback by endocytosis in planar cell polarity signaling is modulated by ubiquitinylation of prickle.
PLoS Genet, 11(5) Art. No. e1005259 (2015)
Open Access   DOI
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Sebastian Dunst
Systematic characterization of of RAB GTPase cell type expression and subcellular localization in Drosophila melanogaster
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2015)
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Helena Khaliullina, Mesut Bilgin, Julio Sampaio, Andrej Shevchenko, Suzanne Eaton
Endocannabinoids are conserved inhibitors of the Hedgehog pathway.
Proc Natl Acad Sci U.S.A., 112(11) 3415-3420 (2015)
DOI
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Marta Maria Swierczynska, Ivona Mateska, M Peitzsch, Stefan Bornstein, Trian Chavakis, G Eisenhofer, Valéria Lamounier-Zepter, Suzanne Eaton
Changes in morphology and function of adrenal cortex in mice fed a high-fat diet.
Int J Obes (Lond), 39(2) 321-330 (2015)
DOI
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Raphael Etournay, Marko Popović, Matthias Merkel, Amitabha Nandi, Corinna Blasse, Benoit Aigouy, Holger Brandl, Gene Myers, Guillaume Salbreux, Frank Jülicher, Suzanne Eaton
Interplay of cell dynamics and epithelial tension during morphogenesis of the Drosophila pupal wing.
Elife, 4 Art. No. e07090 (2015)
Open Access   PDF    DOI

2014

Jonathan Rodenfels, Oksana Lavrynenko, Sophie Ayciriex, Julio Sampaio, Maria Carvalho, Andrej Shevchenko, Suzanne Eaton
Production of systemically circulating Hedgehog by the intestine couples nutrition to growth and development.
Genes Dev, 28(23) 2636-2651 (2014)
DOI
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Suzanne Eaton, Fernando Martin-Belmonte
Cargo sorting in the endocytic pathway: a key regulator of cell polarity and tissue dynamics.
Cold Spring Harb Perspect Biol, 6(10) Art. No. a016899 (2014)
DOI
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Matthias Merkel, Andreas Sagner, Franz Gruber, Raphael Etournay, Corinna Blasse, Gene Myers, Suzanne Eaton, Frank Jülicher
The Balance of Prickle/Spiny-Legs Isoforms Controls the Amount of Coupling between Core and Fat PCP Systems.
Curr Biol, 24(18) 2111-2123 (2014)
DOI
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Daiki Umetsu, Benoit Aigouy, Maryam Aliee, Liyuan Sui, Suzanne Eaton, Frank Jülicher, Christian Dahmann
Local increases in mechanical tension shape compartment boundaries by biasing cell intercalations.
Curr Biol, 24(15) 1798-1805 (2014)
DOI
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Marko Brankatschk, Sebastian Dunst, Linda Nemetschke, Suzanne Eaton
Delivery of circulating lipoproteins to specific neurons in the Drosophila brain regulates systemic insulin signaling.
Elife, 3 Art. No. e02862 (2014)
Open Access   DOI

2013

Marta Maria Swierczynska, Valéria Lamounier-Zepter, Stefan R. Bornstein, Suzanne Eaton
Lipoproteins and Hedgehog signalling - possible implications for the adrenal gland function.
Eur J Clin Invest, 43(11) 1178-1183 (2013)
DOI
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Wilhelm Palm, Marta Maria Swierczynska, Veena Kumari, Monika Ehrhart-Bornstein, Stefan R. Bornstein, Suzanne Eaton
Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals
PLoS Biol, 11(3) Art. No. e1001505 (2013)
Open Access   DOI

2012

Magdalena M Baer, Wilhelm Palm, Suzanne Eaton, Maria Leptin, Markus Affolter
Microsomal triacylglycerol transfer protein (MTP) is required to expand tracheal lumen in Drosophila in a cell-autonomous manner.
J Cell Sci, 125(Pt 24) 6038-6048 (2012)
DOI
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Wilhelm Palm, Julio Sampaio, Marko Brankatschk, Maria Carvalho, Ali Mahmoud, Andrej Shevchenko, Suzanne Eaton
Lipoproteins in Drosophila melanogaster-Assembly, Function, and Influence on Tissue Lipid Composition
PLoS Genet, 8(7) Art. No. e1002828 (2012)
Open Access   DOI
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Andreas Sagner, Matthias Merkel, Benoit Aigouy, Julia Gaebel, Marko Brankatschk, Frank Jülicher#, Suzanne Eaton#
Establishment of Global Patterns of Planar Polarity during Growth of the Drosophila Wing Epithelium.
Curr Biol, 22(14) 1296-1301 (2012)
DOI
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Maria Carvalho✳︎, Julio Sampaio✳︎, Wilhelm Palm, Marko Brankatschk, Suzanne Eaton#, Andrej Shevchenko#
Effects of diet and development on the Drosophila lipidome
Mol Syst Biol, 8 Art. No. 600 (2012)
Open Access   DOI

2011

Suzanne Eaton, Frank Jülicher
Cell flow and tissue polarity patterns.
Curr Opin Genet Dev, 21(6) 747-752 (2011)
DOI
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Wilhelm Palm
The Lipoprotein Metabolism of Drosophila Melanogaster
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2011)
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Benoit Aigouy, Raphael Etournay, Andreas Sagner, Douglas B Staple, Reza Farhadifar, Jens-Christian Röper, Suzanne Eaton, Frank Jülicher
[Cell flow reorients planar polarity in the wing of Drosophila]
Med Sci (Paris), 27(2) 117-119 (2011)
DOI
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Veena Kumari
Discovery of a novel form of Hedgehog that systemically circulates, and its signaling implications in Drosophila
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2011)
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Falko Riedel, Daniela Vorkel, Suzanne Eaton
Megalin-dependent yellow endocytosis restricts melanization in the Drosophila cuticle.
Development, 138(1) 149-158 (2011)
DOI

2010

Maria Carvalho, Dominik Schwudke, Julio Sampaio, Wilhelm Palm, Isabelle Riezman, Gautam Dey, Gagan D Gupta, Satyajit Mayor, Howard Riezman, Andrej Shevchenko, Teymuras V. Kurzchalia#, Suzanne Eaton#
Survival strategies of a sterol auxotroph.
Development, 137(21) 3675-3685 (2010)
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Helena Khaliullina
Patched-mediated regulation of Smoothened trafficking and activity by Lipophorin-derived lipids
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2010)
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Douglas B Staple, Reza Farhadifar, Jens-Christian Röper, Benoit Aigouy, Suzanne Eaton, Frank Jülicher
Mechanics and remodelling of cell packings in epithelia.
Eur Phys J E Soft Matter, 33(2) 117-127 (2010)
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Benoit Aigouy, Reza Farhadifar, Douglas B Staple, Andreas Sagner, Jens-Christian Röper, Frank Jülicher, Suzanne Eaton
Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila.
Cell, 142(5) 773-786 (2010)
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Marko Brankatschk, Suzanne Eaton
Lipoprotein particles cross the blood-brain barrier in Drosophila.
J Neurosci, 30(31) 10441-10447 (2010)
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Giovanna Mottola, Anne-Kathrin Classen, Marcos González-Gaitán, Suzanne Eaton, Marino Zerial
A novel function for the Rab5 effector Rabenosyn-5 in planar cell polarity.
Development, 137(14) 2353-2364 (2010)
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2009

Helena Khaliullina, Daniela Panáková, Christina Eugster, Falko Riedel, Maria Carvalho, Suzanne Eaton
Patched regulates Smoothened trafficking using lipoprotein-derived lipids.
Development, 136(24) 4111-4121 (2009)
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Rodrigo Fernandez-Gonzalez, Sérgio de Matos Simoes, Jens-Christian Röper, Suzanne Eaton, Jennifer A Zallen
Myosin II dynamics are regulated by tension in intercalating cells.
Dev Cell, 17(5) 736-743 (2009)
PDF    DOI
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Jens-Christian Röper
The influence of cell mechanics, cell-cell interactions, and proliferation on epithelial packing
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2009)
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Maria Carvalho
Sterol requirements in Drosophila melanogaster
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2009)
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Falko Riedel
Core members of the Drosophila melanogaster LDL receptor family and their function in wing development
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2009)

2008

Suzanne Eaton
Multiple roles for lipids in the Hedgehog signalling pathway.
Nat Rev Mol Cell Biol, 9(6) 437-445 (2008)
PDF    DOI
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Suzanne Eaton
Retromer retrieves wntless.
Dev Cell, 14(1) 4-6 (2008)
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Anne-Kathrin Classen, Benoit Aigouy, Angela Giangrande, Suzanne Eaton
Imaging Drosophila pupal wing morphogenesis
In: Drosophila : Methods and Protocols. (Eds.) Christian Dahmann Methods in molecular biology ; 420.,Totowa, USA,Humana Press (2008),265-275 Ch. 16
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2007

Reza Farhadifar✳︎, Jens-Christian Röper✳︎, Benoit Aigouy, Suzanne Eaton, Frank Jülicher
The influence of cell mechanics, cell-cell interactions, and proliferation on epithelial packing.
Curr Biol, 17(24) 2095-2104 (2007)
PDF    DOI
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Thomas E Willnow#, Annette Hammes, Suzanne Eaton#
Lipoproteins and their receptors in embryonic development: more than cholesterol clearance.
Development, 134(18) 3239-3249 (2007)
PDF    DOI
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Christina Eugster, Daniela Panáková, Ali Mahmoud, Suzanne Eaton
Lipoprotein-heparan sulfate interactions in the Hh pathway.
Dev Cell, 13(1) 57-71 (2007)
PDF    DOI
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Eric Marois, Suzanne Eaton
RNAi in the Hedgehog signaling pathway: pFRiPE, a vector for temporally and spatially controlled RNAi in Drosophila
In: Hedgehog signaling protocols. (Eds.) Jamila I. Horabin Methods in molecular biology ; 397.,Totowa, USA,Humana Press (2007),115-128 Ch. 10
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2006

Anne-Kathrin Classen
Hexagonal packing of drosophila wing epithelial cells by the planar cell polarity pathway
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2006)
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Suzanne Eaton
Release and trafficking of lipid-linked morphogens.
Curr Opin Genet Dev, 16(1) 17-22 (2006)
PDF    DOI
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Eric Marois, Ali Mahmoud, Suzanne Eaton
The endocytic pathway and formation of the Wingless morphogen gradient.
Development, 133(2) 307-317 (2006)
PDF    DOI

2005

Anne-Kathrin Classen, Kurt I. Anderson, Eric Marois, Suzanne Eaton
Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway.
Dev Cell, 9(6) 805-817 (2005)
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Daniela Panáková✳︎, Hein Sprong✳︎, Eric Marois, Christoph Thiele, Suzanne Eaton
Lipoprotein particles are required for Hedgehog and Wingless signalling.
Nature, 435(7038) 58-65 (2005)
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Chandrashekhar Joglekar
Widerborst Interacts With Bitesize To Regulate Wing Hair Morphogenesis
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2005)
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Daniela Panáková
Lipoprotein particles associate with lipid-lined proteins and are required for long-range Wingless and Hedgehog signaling
Ph.D. Thesis,Technische Universität Dresden, Dresden, Germany (2005)
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2004

Gishnu Das, Andreas Jenny, Thomas J Klein, Suzanne Eaton, Marek Mlodzik
Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes.
Development, 131(18) 4467-4476 (2004)
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2003

Suzanne Eaton
Cell biology of planar polarity transmission in the Drosophila wing.
Mech Dev, 120(11) 1257-1264 (2003)
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Lilianna Solnica-Krezel, Suzanne Eaton
Embryo morphogenesis: getting down to cells and molecules.
Development, 130(18) 4229-4233 (2003)
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Hein Sprong, Sophie Degroote, Tommy Nilsson, Masao Kawakita, Nobuhiro Ishida, Peter van der Sluijs, Gerrit van Meer
Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum.
Mol Biol Cell, 14(8) 3482-3493 (2003)
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Magdalena Deneka, Maaike Neeft, Ioana Popa, Masja van Oort, Hein Sprong, Viola Oorschot, Judith Klumperman, Peter Schu, Peter van der Sluijs
Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes.
EMBO J, 22(11) 2645-2657 (2003)
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2002

Michael Hannus, Fabian Feiguin, Carl-Philipp Heisenberg, Suzanne Eaton
Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A.
Development, 129(14) 3493-3503 (2002)
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2001

Valentina Greco, Michael Hannus, Suzanne Eaton
Argosomes: a potential vehicle for the spread of morphogens through epithelia.
Cell, 106(5) 633-645 (2001)
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Fabian Feiguin, Michael Hannus, Marek Mlodzik, Suzanne Eaton
The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization.
Dev Cell, 1(1) 93-101 (2001)
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1999

N Paricio, Fabian Feiguin, Michael Boutros, Suzanne Eaton, Marek Mlodzik
The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling.
EMBO J, 18(17) 4669-4678 (1999)
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Anton Rietveld, Stephanie Neutz, Kai Simons, Suzanne Eaton
Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.
J Biol Chem, 274(17) 12049-12054 (1999)
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