Research Groups

Metabolomics in C. elegans by LC-MS

Levels of intracellular metabolites directly reflect cell’s physiological state and thus integrates all levels of regulation. Major interest of our study is using C. elegans as a model system to understand the biogenesis and the metabolism of several classes of molecules in the context of different physiological stimuli. We develop LC-MS/MS methods for targeted quantification of  key metabolites, including carbonyl compounds, carbohydrates and nucleotides and purine/pyrimidine pathway intermediates, to mention only a few.

Sofia Traikov