Research Groups

Plasma lipidome of healthy males and females is different

Lipidomics profiling of human blood plasma is widely used for monitoring metabolism perturbations and biomarker discovery. But, are the lipidomes of males and females different, and if yes, what lipid molecules are affected? And, are the individual lipidomes altered by the level of sex hormones? We systematically studied the plasma lipidome composition of healthy young individuals and found that the concentration of ca 50% out of 281 quantified molecules is significantly different between male and female cohorts.

Susanne Sales

Original Publication

Susanne Sales, Juergen Graessler, Sara Ciucci, Rania Al-Atrib, Terhi Vihervaara, Kai Schuhmann, Dimple Kauhanen, Marko Sysi-Aho, Stefan R. Bornstein, Marc Bickle, Carlo V. Cannistraci, Kim Ekroos & Andrej Shevchenko. Gender, Contraceptives and Individual Metabolic Predisposition Shape a Healthy Plasma Lipidome. Sci. Rep. 6, 27710; doi: 10.1038/srep27710 (2016).