Dresden research team finds that the cell cortex, a fine network of filaments below the cell membrane, is activated in a controlled way by thousands of short-lived protein condensates.
Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.
Dresden and Leipzig researchers find that stem cells in the developing brain of modern humans take longer to divide and make fewer errors when distributing their chromosomes to their daughter cells, compared to those of Neanderthals.
The director at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden receives the award for the discovery of condensates - cell droplets without a membrane, a new hope for the treatment of neurodegenerative diseases.
New study identifies two genes, previously reported to be involved in cancer, as regulators of the metabolic state of the liver. Alterations in these genes influence the likelihood of developing fatty liver disease.
Researchers have found where and how mRNA arrives in a cell to modify or deliver genetic information, a crucial process for the development of novel therapies.