MS Community Dresden:

The MS Community provides support to biological and clinical research projects carried at the Campus. It comprises MS-Facilities and MS-research groups from the MPI CBG, UKD, CMCB (TUD), CRTD and NCT, and Lipotype GmbH. The sites host more than 20 high-end MS instruments and have expertise in MS-based Lipidomics, Proteomics and Metabolomics. We work on service base and open for research collaborations. To our activities belong regular meetings, organization of ms-events, MS journal club and scientific consulting.

2021

X'Mass updates 2021 (hybrid format)

Host: Andrej Shevchenko
Speakers: TBA, please send your suggestions to clinical.lipidomicsmpi-cbg.de by mid November
Date and time: 07.12.2021, TBA
Location: https://zoom.us/j/5587099875 and MPI-CBG

MS Community welcomes: Dr. Wei Gao

Host: Andrej Shevchenko
Speaker: Dr. Wei Gao, a leader of MS unit at the Faculty of Psychology, TU Dresden
Topic: Research of stress biomarker based on LC-MS/MS
Date and time: 30.11.2021, 14:00.
Location: https://zoom.us/j/5587099875

The Lipidomics Webinar #3: Why Population Health Studies Must Include Lipidomics

Speaker: Christian Klose
Topic: Population health studies frequently rely on omics technologies but biomarker identification studies benefit only if the data are of high quality and reliably reproducible.
Date and time: 02.12.2021 17:00
More info and Registration: www.lipotype.com/lipidomics-webinars/why-population-health-studies-must-run-lipidomics

MS Community welcomes: Dr. Maria Fedorova

Host: Andrej Shevchenko
Speaker: Maria Fedorova, a group leader at the Center of Membrane Biochemistry and Lipid Research at the Medical Faculty of the TU Dresden
Topic: Lipid metabolism: analysis and integration
Date and time: 16.11.2021, 14:00.
Location: https://zoom.us/j/5587099875

The Lipidomics Webinar #2: Mouse Lipidomics: A Perfect Match?

Speaker: Christian Klose
Topic: Mouse has shown a remarkable specificity of lipids in different cells, tissues, and organs. The mouse lipidomics atlas facilitates experimental design and interpretation in mouse studies.
Date and time: 19.10.2021 17:00
More info and Registration: www.lipotype.com/lipidomics-webinars/mouse-lipidomics-for-clinical-research/

Journal club

Host: Canan Has
Topic: New open-source tools for MS-based proteomics
Paper: https://www.nature.com/articles/s41467-021-22303-zhttps://doi.org/10.1093/bioinformatics/btab674
https://doi.org/10.1101/2021.07.23.453379https://www.nature.com/articles/s41467-021-22303-z
www.nature.com/articles/s41467-021-22303-z
Date and time: 12.10.2020, 14:00.
Location: ZOOM https://zoom.us/j/5587099875

MS Summer digest

3 talks 3 minutes each:
1. Dr. Marc: NHS-Ester Tandem Labeling in One Pot Enables 48-Plex Quantitative Proteomics
2. Dr. Kai: Isomer Selective Comprehensive Lipidomics Analysis of Phosphoinositides in Biological Samples by Liquid Chromatography with Data Independent Acquisition Tandem Mass Spectrometry
3. pre-Dr. Tobi: Ultra-fast proteomics with Scanning SWATH
4. Q&A and general discussion

Date and time: 28.09.2021 14:00
Location: ZOOM https://zoom.us/j/5587099875

The Lipidomics Webinar #1: Lipids are Cool Again

Speaker: Kai Simons
Topic: Lipid metabolism homeostasis is essential for life, but the ongoing obesity pandemic threatens it. Blood lipidomics profiles may help stem the obesity affliction. Lipids are coming back.
Date and time: 21.09.2021 17:00
More info and Registration: https://www.lipotype.com/lipidomics-webinars/introduction-to-lipids-and-lipidomics/

MS4U Discussion club: Mass Cytometry

Host: Andrej Shevchenko
Speaker: Claudia Peitzsch
Topic: Introduction to the suspension mass cytometry method
Paper: https://www.nature.com/articles/s41467-021-22303-z
Date and time: 08.06.2020, 14:00.
Location: ZOOM https://zoom.us/j/5587099875

MS4U Discussion club: Organoids Omics

Agenda:
1. Olya will talk about Lipidomics and Organoids  ~15 mins
2. Sofia will talk about Metabolomics and Organoids  ~15 mins
3. Ignacy will talk about Proteomics and Organoids  ~15 mins
4. Q&A and general discussion

Date and time: 01.06.2021 14:00
Location: ZOOM https://zoom.us/j/5587099875

Journal club

Host: Kai
Topic: A combined flow injection/reversed-phase chromatography-high-resolution mass spectrometry workflow for accurate absolute lipid quantification with 13C internal standards
Paper: https://pubs.rsc.org/en/content/articlehtml/2021/an/d0an02443k 
Date and time: 20.04.2021, 14:00.
Location: ZOOM https://zoom.us/j/5587099875

Journal club

Host: Andrej
Topic: Hybrid QconCAT-Based Targeted Absolute and Data-Independent Acquisition-Based Label-Free Quantification Enables In-Depth Proteomic Characterization of Wheat Amylase/Trypsin Inhibitor Extracts
Paper: https://pubs.acs.org/doi/full/10.1021/acs.jproteome.0c00752 
Date and time: 13.04.2021, 14:00.
Location: ZOOM https://zoom.us/j/5587099875

Journal club

Host: Olya
Topic: LIPIC: An Automated Workflow to Account for Isotopologue-Related Interferences in Electrospray Ionization High-Resolution Mass Spectra of Phospholipids
Paper: https://pubs.acs.org/doi/abs/10.1021/jasms.1c00008
Date and time: 06.04.2021, 14:00.
Location: ZOOM https://zoom.us/j/5587099875

MS4U Discussion club: protein cross-linking

Agenda:
1. Overview of XL-MS methods: principles, limitations, software
2. Application
Guest stars: - Alexander von Appen (Alex starts his lab here in a few weeks) and Adrian Nievergelt (Pigino group) - will talk how XL-MS could foster their research
3. Q&A and general discussion

Host: MS Community
Topic: Protein cross-linking
Date and time: 23.03.2021 14:00
Location: ZOOM https://zoom.us/j/5587099875

Journal club

Host: Olya
Topic: AI-driven Deep Visual Proteomics defines cell identity and heterogeneity
Paper: https://www.biorxiv.org/content/10.1101/2021.01.25.427969v1.full.pdf
Date and time: 16.02.2021, 14:00.
Location: ZOOM https://zoom.us/j/5587099875

MS4U Journal club

Host: Sarita Hebbar (Knust lab) and MS Community
Topic: Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes
Paper: https://www.pnas.org/content/pnas/115/34/E7978.full.pdf
Date and time: 02.02.2021, 14:00.
Location: ZOOM https://zoom.us/j/5587099875

Omics Flash Talks 2021

Our annual get-together in the format of flash talks. Please join our friendly talks, share the news on your omics scientific landscape and stay connected.

Host: Andrej Shevchenko
Date and time: 26.01.2020, 14:00-17:00.
Location: ZOOM https://zoom.us/j/5587099875

Journal club

Host: Bharath
Topic: Quantitative shotgun proteome analysis by direct infusion
Paper: https://www.nature.com/articles/s41592-020-00999-z
Date and time: 19.01.2021, 14:00.
Location: ZOOM https://zoom.us/j/5587099875

The JC rules are the following:

1. The assigned person choses the paper in advance and sends it around, but does not present it.
2. Most importantly, Everyone Reads the Paper!
3. Starting person (randomly chosen) describes (questiones, criticizes) the first figure/paragraph/topic, and all together we try to figure out what authors wanted to say. The second person (randomly chosen) describes the second figure and so on.
4. Please come if you read the paper.
5. If you bring your colleagues or friends, make sure that they are aware of the rules.