Research Groups

* joined first author # joined corresponding author

2021

Christoph A. Weber, Christoph Zechner
Drops in cells.
Physics Today , 74(6) 38-43 (2021)
DOI
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Tobias Pietzsch, Lorenzo Duso, Christoph Zechner
Compartor: A toolbox for the automatic generation of moment equations for dynamic compartment populations.
Bioinformatics, 37(17) 2782-2784 (2021)
Open Access   DOI
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Anders S Hansen#, Christoph Zechner#
Promoters adopt distinct dynamic manifestations depending on transcription factor context.
Mol Syst Biol, 17(2) Art. No. e9821 (2021)
Open Access   DOI

2020

David Thomas Gonzales, Christoph Zechner, T-Y Dora Tang
Building synthetic multicellular systems usingbottom–up approaches.
Curr Opin Syst Biol, 24 56-63 (2020)
Open Access   DOI
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Lorenzo Duso, Christoph Zechner
Stochastic reaction networks in dynamic compartment populations.
Proc Natl Acad Sci U.S.A., 117(37) 22674-22683 (2020)
Open Access   DOI
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Christoph Zechner#, Elisa Nerli, Caren Norden#
Stochasticity and determinism in cell fate decisions.
Development, 147(14) Art. No. dev181495 (2020)
DOI
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Mohammadreza Bahadorian, Christoph Zechner#, Carl D. Modes#
Gift of gab: Probing the limits of dynamic concentration-sensing across a network of communicating cells.
Phys Rev Research, 2(2) Art. No. 023403 (2020)
Open Access   DOI
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Adam Klosin✳︎, F Oltsch✳︎, T Harmon, Alf Honigmann, Frank Jülicher#, Anthony A. Hyman#, Christoph Zechner#
Phase separation provides a mechanism to reduce noise in cells.
Science, 367(6476) 464-468 (2020)
DOI

2019

Lorenzo Duso, Christoph Zechner
Path mutual information for a class of biochemical reaction networks.
In: 2019 IEEE 58th Conference on Decision and Control (CDC) (2019)(Eds.) Carlos A. Canudas de Wit, Piscataway, N.J., IEEE (2019), 6610-6615
DOI
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David Thomas Gonzales, T-Y Dora Tang, Christoph Zechner
Moment-based analysis of biochemical networks in a heterogeneous population of communicating cells.
In: 2019 IEEE 58th Conference on Decision and Control (CDC) (2019)(Eds.) Carlos A. Canudas de Wit, Piscataway, N.J., IEEE (2019), 939-944
DOI
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Giorgio Fracasso, Yvonne Körner, David Thomas Gonzales, T-Y Dora Tang
In vitro gene expression and detergent-free reconstitution of active proteorhodopsin in lipid vesicles.
Exp. Biol. Med. (Maywood), 244(4) 314-322 (2019)
DOI
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Dimitrios Papadopoulos#, Kassiani Skouloudaki, Ylva Engström, Lars Terenius, Rudolf Rigler, Christoph Zechner, Vladana Vukojević, Pavel Tomancak#
Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch.
Development, 146(12) Art. No. dev168179 (2019)
DOI

2018

Lorenzo Duso, Christoph Zechner
Selected-node stochastic simulation algorithm.
J Chem Phys, 148(16) Art. No. 164108 (2018)
DOI

2017

L Carine Stapel, Christoph Zechner, Nadine Vastenhouw
Uniform gene expression in embryos is achieved by temporal averaging of transcription noise.
Genes Dev, 31(16) 1635-1640 (2017)
DOI
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Irena Kuzmanovska, Andreas Milias-Argeitis, Jan Mikelson, Christoph Zechner, Mustafa Khammash
Parameter inference for stochastic single-cell dynamics from lineage tree data.
BMC Syst Biol, 11(1) Art. No. 52 (2017)
Open Access   DOI
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Jakob Ruess✳︎#, Heinz Koeppl, Christoph Zechner✳︎#
Sensitivity estimation for stochastic models of biochemical reaction networks in the presence of extrinsic variability.
J Chem Phys, 146(12) Art. No. 124122 (2017)
DOI

2016

Christoph Zechner, Georg Seelig, Marc Rullan, Mustafa Khammash
Molecular circuits for dynamic noise filtering.
Proc Natl Acad Sci U.S.A., 113(17) 4729-4734 (2016)
DOI

2014

Christoph Zechner, Heinz Koeppl
Uncoupled analysis of stochastic reaction networks in fluctuating environments.
PLoS Comput Biol, 10(12) Art. No. e1003942 (2014)
Open Access   PDF    DOI
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Christoph Zechner, Maria F Unger, Serge Pelet, Matthias Peter, Heinz Koeppl
Scalable inference of heterogeneous reaction kinetics from pooled single-cell recordings.
Nat Methods, 11(2) 197-202 (2014)
DOI

2012

Christoph Zechner, Jakob Ruess, Peter Krenn, Serge Pelet, Matthias Peter, John Lygeros, Heinz Koeppl
Moment-based inference predicts bimodality in transient gene expression.
Proc Natl Acad Sci U.S.A., 109(21) 8340-8345 (2012)
DOI