DeutschEnglish

Suzanne Eaton

Long-range cell communication and tissue organization in the developing wing of Drosophila

The broad interest of my lab is to understand the cell biological mechanisms that organize global patterns in developing tissues.

We are focused on two aspects of drosophila wing development:
1) the role of membrane trafficking in shaping of morphogen gradients in the larval wing disc, and
2) mechanisms of junction remodeling and tissue polarization during pupal morphogenesis.

Imaginal disc (wing pouch)

Selected Publications

2007
Eugster, Christina; Panáková, Daniela; Mahmoud, Ali; Eaton, Suzanne
Lipoprotein-heparan sulfate interactions in the Hh pathway.
Dev. Cell, 13, no. 1, pp. 57-71, (2007)
Download PDF
2006
Marois, Eric; Mahmoud, Ali; Eaton, Suzanne
The endocytic pathway and formation of the Wingless morphogen gradient.
Development, 133, no. 2, pp. 307-317, (2006)
Download PDF
2005
Panáková, Daniela; Sprong, Hein; Thiele, Christoph; Eaton, Suzanne; Marois, Eric
Lipoprotein particles are required for Hedgehog and Wingless signalling.
Nature, 435, no. 7038, pp. 58-65, (2005)
Download PDF
2002
Hannus, Michael; Feiguin, Fabian; Heisenberg, Carl-Philipp; Eaton, Suzanne
Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A.
Development, 129, no. 14, pp. 3493-3503, (2002)
Download PDF
2001
Greco, Valentina; Hannus, Michael; Eaton, Suzanne
Argosomes: a potential vehicle for the spread of morphogens through epithelia.
Cell, 106, no. 5, pp. 633-645, (2001)
Download PDF
1999
Rietveld, Anton; Neutz, Stephanie; Simons, Kai; Eaton, Suzanne
Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.
J. Biol. Chem., 274, no. 17, pp. 12049-12054, (1999)
Download PDF