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Frank Buchholz

Frank Buchholz

Research Group Leader

Scientific Carreer

01/2002 - present

Max Planck Institute for Molecular Cell Biology and Genetics (MPI-CBG)
Group Leader
Research: "Programming and re-programming of mammalian cells in vitro and in vivo"

05/1998 - 12/2001

UNIVERSITY OF CALIFORNIA SAN FRANCISCO (UCSF), The G. W. Hooper Foundation (USA)
Postdoctoral research
Research: "A conditional mouse model for t(8;21) induced leukemia using Cre/loxP technology"
Mentor: Prof. J. Michael Bishop
Funding: Leukemia and Lymphoma Society fellowship

04/1994 - 05/1998

EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL), Gene Expression Program, Heidelberg (Germany)
Postdoctoral research (12/1997 - 05/1998)
Research: "Generation of designer recombinases through directed molecular evolution"
Mentor: Dr. A. Francis Stewart
Funding: EMBL postdoctoral fellowship


Education


04/1994 - 12/1997

PhD Thesis
Title: "Investigation and development of site specific recombinases for advanced genomic engineering"
Supervisor: Dr. A. Francis Stewart
Funding: EMBL PhD program fellowship

08/1987- 06/1993

UNIVERSITY OF GÖTTINGEN Department of Molecular Genetics (Germany)
UNIVERSITY OF CALIFORNIA SAN DIEGO (UCSD) Department of Molecular Medicine (USA)

09/1991 - 12/1992

Diploma Thesis
Title: "Identifizierung, Klonierung und Charakterisierung des gewebespezifisch exprimierten Gens zipI der Ratte"
Supervisor: Prof. Michael G. Rosenfeld and Prof. Hans J. Fritz
Funding: Education abroad program (EAP), Fulbright fellowship

08/1987 - 06/1993

UNIVERSITY OF GÖTTINGEN, Biology Faculty (Germany)
Biology degree


Honors and Awards


2003

Research grant of the "Deutsche Jose Carreras Leukämie-Stiftung e.V."

2002

Group Leader position at the Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany

1998

Leukemia and Lymphoma Society postdoctoral fellowship
Postdoctoral position at EMBL (European Molecular Biology Laboratory), Heidelberg (Germany)

1997

PhD in Biology from the University in Heidelberg, Germany

1994

Ph.D. position at the EMBL (European Molecular Biology Laboratory), Heidelberg, Germany
EMBL Ph.D. program fellowship-recipient

1993

Diploma thesis in Biology, Göttingen, Germany

1991

Education abroad program (EAP) fellowship
Fulbright fellowship


Patents


Stewart,-AF; Zhang-Y; Buchholz- F
"Novel DNA cloning method"
Granted international patent PCT/EP98/07945

Stewart,-AF; Buchholz- F
"Substrate linked directed evolution (SliDE)"
Approved in UK WO0244409