| 2012 |
| Gerl, Mathias J.; Sampaio, Julio; Kalvodova, Lucie; Verbavatz, Jean-Marc; Shevchenko, Andrej; Schroeder, Cornelia; Simons, Kai |
| Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane |
| J. Cell Biol., pp. 1-1, (2012) |
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| 2011 |
| Hyman, Anthony A.; Simons, Kai |
| The new cell biology: Beyond HeLa cells. |
| Nature, 480, no. 7375, pp. 34-34, (2011) |
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| Kaiser, Hermann-Josef; Surma, Michal; Levental, Ilya; Grzybek, Michal; Klemm, Robin W.; Lingwood, Daniel; Simons, Kai |
| Molecular convergence of bacterial and eukaryotic surface order. |
| JBC, 286, no. 47, pp. 40631-40637, (2011) |
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|
| The Biology of Lipids Trafficking, Regulation, and Function |
| (2011) |
| Download PDFDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text FileDownload Supplementary Text File |
| Coskun, Uenal; Grzybek, Michal; Simons, Kai; Drechsel, David N. |
| Regulation of human EGF receptor by lipids |
| Proc. Natl. Acad. Sci. U.S.A., 108, no. 22, pp. 9044-9048, (2011) |
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| Grzybek, Michal; Levental, Ilya; Simons, Kai |
| Raft domains of variable properties and compositions in plasma membrane vesicles |
| Proc. Natl. Acad. Sci. U.S.A., 108, no. 28, pp. 11411-11416, (2011) |
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| Sampaio, Julio; Simons, Kai |
| Membrane Organization and Lipid Rafts |
| The Biology of Lipids, chapt. 1, pp. 1-17, (2011) |
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| Sampaio, Julio; Klose, Christian; Simons, Kai; Gerl, Mathias J.; Ejsing, Christer S.; Shevchenko, Andrej |
| Membrane lipidome of an epithelial cell line |
| Proc. Natl. Acad. Sci. U.S.A., 108, no. 5, pp. 1903--1907, (2011) |
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| Surma, Michal; Klose, Christian; Klemm, Robin W.; Ejsing, Christer S.; Simons, Kai |
| Generic Sorting of Raft Lipids into Secretory Vesicles in Yeast |
| Traffic, 12, no. 9, pp. 1139-1147, (2011) |
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| Lingwood, Daniel; Coskun, Uenal; Grzybek, Michal; Simons, Kai |
| Cholesterol modulates glycolipid conformation and receptor activity |
| Nature chem. Bio., 5, pp. 260-262, (2011) |
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| 2010 |
| Fraldi, Alessandro; Annunziata, Fabio; Lombardi, Alessia; Kaiser, Hermann-Josef; Medina, Diego Luis; Spampanato, Carmine; Fedele, Anthony Olind; Polishchuk, Roman; Sorrentino, Nicolina Cristina; Simons, Kai; Ballabio, Andrea |
| Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders. |
| EMBO J., 29, no. 21, pp. 3607-3620, (2010) |
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| Simons, Kai |
| Engineering the Future with Cell Biology |
| Mol. Biol. Cell, 21, no. 22, pp. 3822-3822, (2010) |
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| Simons, Kai; Gerl, Mathias J. |
| Revitalizing membrane rafts: new tools and insights |
| Nat. Rev. Mol. Cell Biol., 11, no. 10, pp. 688-699, (2010) |
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| Levental, Ilya; Lingwood, Daniel; Grzybek, Michal; Coskun, Uenal; Simons, Kai |
| Palmitoylation regulates raft affinity for the majority of integral raft proteins |
| Proc. Natl. Acad. Sci. U.S.A., 107, no. 51, pp. 22050-22054, (2010) |
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| Mishra, Rashmi; Grzybek, Michal; Niki, Toshiro; Hirashima, Mitsuomi; Simons, Kai |
| Galectin-9 trafficking regulates apical-basal polarity in Madin-Darby canine kidney epithelial cells |
| Proc. Natl. Acad. Sci. U.S.A., 107, no. 41, pp. 17633-17638, (2010) |
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| Klose, Christian; Ejsing, Christer S.; Garcia-Sáez, Anna J.; Kaiser, Hermann-Josef; Sampaio, Julio; Surma, Michal; Shevchenko, Andrej; Schwille, Petra; Simons, Kai |
| Yeast lipids can phase-separate into micrometer-scale membrane domains |
| J. Biol. Chem., 285, no. 39, pp. 30224-30232, (2010) |
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| Shevchenko, Andrej; Simons, Kai |
| Lipidomics: coming to grips with lipid diversity. |
| Nat. Rev. Mol. Cell Biol., 11, no. 8, pp. 593-598, (2010) |
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| Levental, Ilya; Grzybek, Michal; Simons, Kai |
| Greasing their way: lipid modifications determine protein association with membrane rafts |
| Biochemistry, 49, no. 30, pp. 6305-6316, (2010) |
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| Sampaio, Julio |
| The role of lipids in cellular architecture and function |
| [Doctoral Thesis] Technische Universität Dresden, (2010) |
| Kaiser, Hermann-Josef |
| Membrane order and domain formation in cholesterol-containing membranes |
| [Doctoral Thesis] Technische Universität Dresden, (2010) |
| Horlacher, Tim; Oberli, Matthias A; Werz, Daniel B; Kröck, Lenz; Bufali, Simone; Mishra, Rashmi; Sobek, Jens; Simons, Kai; Hirashima, Mitsuomi; Niki, Toshiro; Seeberger, Peter H |
| Determination of carbohydrate-binding preferences of human galectins with carbohydrate microarrays. |
| Chembiochem, 11, no. 11, pp. 1563-1573, (2010) |
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| Coskun, Uenal; Simons, Kai |
| Membrane rafting: from apical sorting to phase segregation. |
| FEBS Lett., 584, no. 9, pp. 1685-1693, (2010) |
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| Lenoir, Marc; Coskun, Uenal; Grzybek, Michal; Cao, Xinwang; Buschhorn, Sabine Barbara; James, Jonathan; Simons, Kai; Overduin, Michael |
| Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains. |
| EMBO Rep., 11, no. 4, pp. 279-284, (2010) |
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| Simons, Kai |
| New beginnings: getting the kick I needed |
| Nat. Cell Biol., 12, no. 3, pp. 202-202, (2010) |
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| Breslow, David K.; Collins, Sean R.; Bodenmiller, Bernd; Aebersold, Ruedi; Simons, Kai; Shevchenko, Andrej; Ejsing, Christer S.; Weissman, Jonathan S. |
| Orm family proteins mediate sphingolipid homeostasis |
| Nature, 463, no. 7284, pp. 1048-1053, (2010) |
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| Simons, Kai |
| My life on a raft |
| Scientist, 24, no. 2, pp. 24-24, (2010) |
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| Rajendran, Lawrence; Knölker, Hans-Joachim; Simons, Kai |
| Subcellular targeting strategies for drug design and delivery. |
| Nat Rev Drug Discov, 9, no. 1, pp. 29-42, (2010) |
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| Lingwood, Daniel; Simons, Kai |
| Lipid rafts as a membrane-organizing principle. |
| Science, 327, no. 5961, pp. 46-50, (2010) |
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| 2009 |
| Cao, Xinwang; Coskun, Uenal; Rössle, Manfred; Buschhorn, Sabine Barbara; Grzybek, Michal; Dafforn, Timothy R; Lenoir, Marc; Overduin, Michael; Simons, Kai |
| Golgi protein FAPP2 tubulates membranes. |
| Proc. Natl. Acad. Sci. U.S.A., 106, no. 50, pp. 21121-21125, (2009) |
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| Lingwood, Daniel; Schuck, Sebastian; Ferguson, Charles; Gerl, Mathias J.; Simons, Kai |
| Morphological homeostasis by autophagy. |
| Autophagy, 5, no. 7, pp. 1039-1040, (2009) |
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| Lingwood, Daniel; Kaiser, Hermann-Josef; Levental, Ilya; Simons, Kai |
| Lipid rafts as functional heterogeneity in cell membranes. |
| Biochem. Soc. Trans., 37, no. Pt 5, pp. 955-960, (2009) |
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| Kaiser, Hermann-Josef; Lingwood, Daniel; Levental, Ilya; Sampaio, Julio; Kalvodova, Lucie; Rajendran, Lawrence; Simons, Kai |
| Order of lipid phases in model and plasma membranes. |
| Proc. Natl. Acad. Sci. U.S.A., 106, no. 39, pp. 16645-16650, (2009) |
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| Kalvodova, Lucie; Sampaio, Julio; Cordo, Sandra; Ejsing, Christer S.; Shevchenko, Andrej; Simons, Kai |
| The lipidomes of vesicular stomatitis virus, semliki forest virus, and the host plasma membrane analyzed by quantitative shotgun mass spectrometry. |
| J. Virol., 83, no. 16, pp. 7996-8003, (2009) |
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| Ohya, Takeshi; Miaczynska, Marta; Coskun, Uenal; Lommer, Barbara; Runge, Anja; Drechsel, David N.; Kalaidzidis, Yannis; Zerial, Marino |
| Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes. |
| Nature, 459, no. 7250, pp. 1091-1097, (2009) |
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| Klemm, Robin W.; Ejsing, Christer S.; Surma, Michal; Kaiser, Hermann-Josef; Gerl, Mathias J.; Sampaio, Julio; Robillard, Quentin de; Ferguson, Charles; Proszynski, Tomasz J.; Shevchenko, Andrej; Simons, Kai |
| Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network. |
| J. Cell Biol., 185, no. 4, pp. 601-612, (2009) |
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| Lingwood, Daniel; Schuck, Sebastian; Ferguson, Charles; Gerl, Mathias J.; Simons, Kai |
| Generation of cubic membranes by controlled homotypic interaction of membrane proteins in the endoplasmic reticulum. |
| J. Biol. Chem., 284, no. 18, pp. 12041-12048, (2009) |
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| Lingwood, Daniel |
| The activation of organization in cell membranes |
| [Doctoral Thesis] Technische Universität Dresden, (2009) |
| Klose, Christian |
| Membrane organization in yeast |
| [Doctoral Thesis] Technische Universität Dresden, (2009) |
| Ejsing, Christer S.; Sampaio, Julio; Surendranath, Vineeth; Duchoslav, Eva; Ekroos, Kim; Klemm, Robin W.; Simons, Kai; Shevchenko, Andrej |
| Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry. |
| Proc. Natl. Acad. Sci. U.S.A., 106, no. 7, pp. 2136-2141, (2009) |
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| 2008 |
| Simons, Kai |
| The misused impact factor. |
| Science, 322, no. 5899, pp. 165-165, (2008) |
| Download PDF |
| Buschhorn, Sabine Barbara |
| Functional implications of lipid organization in MDCK cells |
| [Doctoral Thesis] Technische Universität Dresden, (2008) |
| Lingwood, Daniel; Ries, Jonas; Schwille, Petra; Simons, Kai |
| Plasma membranes are poised for activation of raft phase coalescence at physiological temperature. |
| Proc. Natl. Acad. Sci. U.S.A., 105, no. 29, pp. 10005-10010, (2008) |
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| Rajendran, Lawrence; Schneider, Anja; Schlechtingen, Georg; Weidlich, Sebastian; Ries, Jonas; Braxmeier, Tobias; Schwille, Petra; Schulz, Jörg B; Schroeder, Cornelia; Simons, Mikael; Jennings, Gary; Knölker, Hans-Joachim; Simons, Kai |
| Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting. |
| Science, 320, no. 5875, pp. 520-523, (2008) |
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| Torkko, Juha M.; Manninen, Aki; Schuck, Sebastian; Simons, Kai |
| Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis. |
| J. Cell. Sci., 121, no. Pt 8, pp. 1193-1203, (2008) |
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| Schneider, Anja; Rajendran, Lawrence; Honsho, Masanori; Gralle, Matthias; Donnert, Gerald; Wouters, Fred; Hell, Stefan W; Simons, Mikael |
| Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons. |
| J. Neurosci., 28, no. 11, pp. 2874-2882, (2008) |
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| Trajkovic, Katarina; Hsu, Chieh; Chiantia, Salvatore; Rajendran, Lawrence; Wenzel, Dirk; Wieland, Felix T.; Schwille, Petra; Brügger, Britta; Simons, Mikael |
| Ceramide triggers budding of exosome vesicles into multivesicular endosomes. |
| Science, 319, no. 5867, pp. 1244-1247, (2008) |
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| Gerl, Mathias J. |
| Membrane domains and traffic in epithelial cells |
| [Doctoral Thesis] Technische Universität Dresden, (2008) |
| 2007 |
| Halter, David; Neumann, Sylvia; Dijk, Suzanne M van; Wolthoorn, Jasja; Mazière, Ann M de; Vieira, Otilia V; Mattjus, Peter; Klumperman, Judith; Meer, Gerrit van; Sprong, Hein |
| Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis. |
| J. Cell Biol., 179, no. 1, pp. 101-115, (2007) |
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| Friedrichs, Jens; Torkko, Juha M.; Helenius, Jonne H.; Teräväinen, Terhi P; Füllekrug, Joachim; Müller, Daniel J. ; Simons, Kai; Manninen, Aki |
| Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy. |
| J. Biol. Chem., 282, no. 40, pp. 29375-29383, (2007) |
| Download PDF |
| Parton, Robert G.; Simons, Kai |
| The multiple faces of caveolae. |
| Nat. Rev. Mol. Cell Biol., 8, no. 3, pp. 185-194, (2007) |
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| Kippert, Angelika; Trajkovic, Katarina; Rajendran, Lawrence; Ries, Jonas; Simons, Mikael |
| Rho regulates membrane transport in the endocytic pathway to control plasma membrane specialization in oligodendroglial cells. |
| J. Neurosci., 27, no. 13, pp. 3560-3570, (2007) |
| Download PDF |
| Rajendran, Lawrence; Lay, Soazig Le; Illges, Harald |
| Raft association and lipid droplet targeting of flotillins are independent of caveolin. |
| Biol. Chem., 388, no. 3, pp. 307-314, (2007) |
| Download PDF |
| Schuck, Sebastian; Gerl, Mathias J.; Ang, Agnes; Manninen, Aki; Keller, Patrick; Mellman, Ira; Simons, Kai |
| Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells. |
| Traffic, 8, no. 1, pp. 47-60, (2007) |
| Download PDF |
| Ejsing, Christer S. |
| Molecular characterization of the lipidome by mass spectrometry |
| [Doctoral Thesis] Technische Universität Dresden, (2007) |
| Download PDF |
| Rajendran, Lawrence; Knobloch, Marlen; Geiger, Kathrin D.; Dienel, Stephanie; Nitsch, Roger; Simons, Kai; Konietzko, Uwe |
| Increased Abeta production leads to intracellular accumulation of Abeta in flotillin-1-positive endosomes. |
| Neuro-degenerative diseases, 4, no. 2-3, pp. 164-170, (2007) |
| Download PDF |
| Lingwood, Daniel; Simons, Kai |
| Detergent resistance as a tool in membrane research |
| Nat. Protoc., 2, no. 9, pp. 2159-2165, (2007) |
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| 2006 |
| Vieira, Otilia V; Gaus, Katharina; Verkade, Paul; Füllekrug, Joachim; Vaz, Winchil L. C.; Simons, Kai |
| FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells. |
| Proc. Natl. Acad. Sci. U.S.A., 103, no. 49, pp. 18556-18561, (2006) |
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| Stetzkowski-Marden, Françoise; Gaus, Katharina; Recouvreur, Michel; Cartaud, Annie; Cartaud, Jean |
| Agrin elicits membrane lipid condensation at sites of acetylcholine receptor clusters in C2C12 myotubes. |
| J. Lipid Res., 47, no. 10, pp. 2121-2133, (2006) |
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| Gaus, Katharina; Lay, Soazig Le; Balasubramanian, Nagaraj; Schwartz, Martin A |
| Integrin-mediated adhesion regulates membrane order. |
| J. Cell Biol., 174, no. 5, pp. 725-734, (2006) |
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| Rajendran, Lawrence; Honsho, Masanori; Zahn, Tobias R.; Keller, Patrick; Geiger, Kathrin D.; Verkade, Paul; Simons, Kai |
| Alzheimer's disease beta-amyloid peptides are released in association with exosomes. |
| Proc. Natl. Acad. Sci. U.S.A., 103, no. 30, pp. 11172-11177, (2006) |
| Download PDF |
| Proszynski, Tomasz J.; Klemm, Robin W.; Bagnat, Michel; Gaus, Katharina; Simons, Kai |
| Plasma membrane polarization during mating in yeast cells. |
| J. Cell Biol., 173, no. 6, pp. 861-866, (2006) |
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| Lay, Soazig Le; Hajduch, Eric; Lindsay, Margaret R; Lièpvre, Xavier Le; Thiele, Christoph; Ferré, Pascal; Parton, Robert G.; Kurzchalia, Teymuras V.; Simons, Kai; Dugail, Isabelle |
| Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis. |
| Traffic, 7, no. 5, pp. 549-561, (2006) |
| Download PDF |
| Meder, Doris; Simons, Kai |
| Lipid Rafts, Caveolae, and Membrane Traffic |
| Lipid Rafts and Caveolae, chapt. 1, pp. 1-23, (2006) |
| Download PDF |
| Schuck, Sebastian; Simons, Kai |
| Controversy fuels trafficking of GPI-anchored proteins. |
| J. Cell Biol., 172, no. 7, pp. 963-965, (2006) |
| Download PDF |
| Ejsing, Christer S.; Moehring, Thomas; Bahr, Ute; Duchoslav, Eva; Karas, Michael; Simons, Kai; Shevchenko, Andrej |
| Collision-induced dissociation pathways of yeast sphingolipids and their molecular profiling in total lipid extracts: a study by quadrupole TOF and linear ion trap-orbitrap mass spectrometry. |
| Journal of mass spectrometry : JMS, 41, no. 3, pp. 372-389, (2006) |
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| Kalvodova, Lucie |
| Reconstituting APP and BACE in proteoliposomes to characterize lipid requirements for ß-secretase activity |
| [Doctoral Thesis] Technische Universität Dresden, (2006) |
| Meder, Doris; Moreno, Maria Joao; Verkade, Paul; Vaz, Winchil L. C.; Simons, Kai |
| Phase coexistence and connectivity in the apical membrane of polarized epithelial cells. |
| Proc. Natl. Acad. Sci. U.S.A., 103, no. 2, pp. 329-334, (2006) |
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| Füllekrug, Joachim; Shevchenko, Anna; Shevchenko, Andrej; Simons, Kai |
| Identification of glycosylated marker proteins of epithelial polarity in MDCK cells by homology driven proteomics. |
| BMC Biochem., 7, pp. 8-8, (2006) |
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| 2005 |
| Simons, Kai; Featherstone, Carol |
| The European research council on the brink. |
| Cell, 123, no. 5, pp. 747-750, (2005) |
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| Kalvodova, Lucie; Kahya, Nicoletta; Schwille, Petra; Ehehalt, Robert; Verkade, Paul; Drechsel, David N.; Simons, Kai |
| Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro. |
| J. Biol. Chem., 280, no. 44, pp. 36815-36823, (2005) |
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| Manninen, Aki; Verkade, Paul; Lay, Soazig Le; Torkko, Juha M.; Kasper, Michael; Füllekrug, Joachim; Simons, Kai |
| Caveolin-1 is not essential for biosynthetic apical membrane transport. |
| Mol. Cell. Biol., 25, no. 22, pp. 10087-10096, (2005) |
| Download PDF |
| Vieira, Otilia V; Verkade, Paul; Manninen, Aki; Simons, Kai |
| FAPP2 is involved in the transport of apical cargo in polarized MDCK cells. |
| J. Cell Biol., 170, no. 4, pp. 521-526, (2005) |
| Download PDF |
| Delacour, Delphine; Gouyer, Valérie; Zanetta, Jean-Pierre; Drobecq, Hervé; Leteurtre, Emmanuelle; Grard, Georges; Moreau-Hannedouche, Odile; Maes, Emmanuel; Pons, Alexandre; André, Sabine; Bivic, André Le; Gabius, Hans Joachim; Manninen, Aki; Simons, Kai; Huet, Guillemette |
| Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells. |
| J. Cell Biol., 169, no. 3, pp. 491-501, (2005) |
| Download PDF |
| Rajendran, Lawrence; Simons, Kai |
| Lipid rafts and membrane dynamics. |
| J. Cell. Sci., 118, no. Pt 6, pp. 1099-1102, (2005) |
| Download PDF |
| Meder, Doris; Simons, Kai |
| Cell biology. Ras on the roundabout. |
| Science, 307, no. 5716, pp. 1731-1733, (2005) |
| Download PDF |
| Proszynski, Tomasz J. |
| Protein sorting and cell surface polarity in yeast |
| [Doctoral Thesis] Technische Universität Dresden, (2005) |
| Meder, Doris; Shevchenko, Anna; Simons, Kai; Füllekrug, Joachim |
| Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells. |
| J. Cell Biol., 168, no. 2, pp. 303-313, (2005) |
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| 2004 |
| Schuck, Sebastian; Simons, Kai |
| Polarized sorting in epithelial cells: raft clustering and the biogenesis of the apical membrane. |
| J. Cell. Sci., 117, no. Pt 25, pp. 5955-5964, (2004) |
| Download PDF |
| Schuck, Sebastian |
| Protein sorting to the apical membrane of epithelial cells |
| [Doctoral Thesis] Technische Universität Dresden, (2004) |
| Poole, Kate; Meder, Doris; Simons, Kai; Müller, Daniel J. |
| The effect of raft lipid depletion on microvilli formation in MDCK cells, visualized by atomic force microscopy. |
| FEBS Lett., 565, no. 1-3, pp. 53-58, (2004) |
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| Proszynski, Tomasz J.; Simons, Kai; Bagnat, Michel |
| O-glycosylation as a sorting determinant for cell surface delivery in yeast. |
| Mol. Biol. Cell, 15, no. 4, pp. 1533-1543, (2004) |
| Download PDF |
| Füllekrug, Joachim; Simons, Kai |
| Lipid rafts and apical membrane traffic. |
| Ann. N. Y. Acad. Sci., 1014, pp. 164-169, (2004) |
| Download PDF |
| Schuck, Sebastian; Manninen, Aki; Honsho, Masanori; Füllekrug, Joachim; Simons, Kai |
| Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference. |
| Proc. Natl. Acad. Sci. U.S.A., 101, no. 14, pp. 4912-4917, (2004) |
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| Meder, Doris |
| Organization and formation of the apical membrane of epithelial cells |
| [Doctoral Thesis] Technische Universität Dresden, (2004) |
| Simons, Kai; Vaz, Winchil L. C. |
| Model systems, lipid rafts, and cell membranes. |
| Annual review of biophysics and biomolecular structure, 33, pp. 269-295, (2004) |
| Download PDF |
| Lommel, Mark; Bagnat, Michel; Strahl, Sabine |
| Aberrant processing of the WSC family and Mid2p cell surface sensors results in cell death of Saccharomyces cerevisiae O-mannosylation mutants. |
| Mol. Cell. Biol., 24, no. 1, pp. 46-57, (2004) |
| 2003 |
| Ekroos, Kim; Ejsing, Christer S.; Bahr, Ute; Karas, Michael; Simons, Kai; Shevchenko, Andrej |
| Charting molecular composition of phosphatidylcholines by fatty acid scanning and ion trap MS3 fragmentation. |
| J. Lipid Res., 44, no. 11, pp. 2181-2192, (2003) |
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| Schuck, Sebastian; Honsho, Masanori; Ekroos, Kim; Shevchenko, Andrej; Simons, Kai |
| Resistance of cell membranes to different detergents. |
| Proc. Natl. Acad. Sci. U.S.A., 100, no. 10, pp. 5795-5800, (2003) |
| Download PDF |
| Lahtinen, Ulla; Honsho, Masanori; Parton, Robert G.; Simons, Kai; Verkade, Paul |
| Involvement of caveolin-2 in caveolar biogenesis in MDCK cells. |
| FEBS Lett., 538, no. 1-3, pp. 85-88, (2003) |
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| Ehehalt, Robert; Keller, Patrick; Haass, Christian; Thiele, Christoph; Simons, Kai |
| Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. |
| J. Cell Biol., 160, no. 1, pp. 113-123, (2003) |
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| 2002 |
| Bagnat, Michel; Simons, Kai |
| Lipid rafts in protein sorting and cell polarity in budding yeast Saccharomyces cerevisiae. |
| Biol. Chem., 383, no. 10, pp. 1475-1480, (2002) |
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| Bagnat, Michel; Simons, Kai |
| Cell surface polarization during yeast mating. |
| Proc. Natl. Acad. Sci. U.S.A., 99, no. 22, pp. 14183-14188, (2002) |
| Download PDF |
| Simons, Kai; Ehehalt, Robert |
| Cholesterol, lipid rafts, and disease. |
| J. Clin. Invest., 110, no. 5, pp. 597-603, (2002) |
| Download PDF |
| Ehehalt, Robert; Michel, Beate; Tonelli, Davide De Pietri; Zacchetti, Daniele; Simons, Kai; Keller, Patrick |
| Splice variants of the beta-site APP-cleaving enzyme BACE1 in human brain and pancreas. |
| Biochem. Biophys. Res. Commun., 293, no. 1, pp. 30-37, (2002) |
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| Ekroos, Kim; Chernushevich, Igor V.; Simons, Kai; Shevchenko, Andrej |
| Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometer. |
| Anal. Chem., 74, no. 5, pp. 941-949, (2002) |
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| 2001 |
| Bagnat, Michel; Chang, Amy; Simons, Kai |
| Plasma membrane proton ATPase Pma1p requires raft association for surface delivery in yeast. |
| Mol. Biol. Cell, 12, no. 12, pp. 4129-4138, (2001) |
| Download PDF |
| Simons, Kai |
| Lessons in science politics. |
| Nat. Rev. Mol. Cell Biol., 2, no. 12, pp. 931-933, (2001) |
| Download PDF |
| Simons, Mikael; Keller, Patrick; Dichgans, Johannes; Schulz, Jörg B |
| Cholesterol and Alzheimer's disease: is there a link? |
| Neurology, 57, no. 6, pp. 1089-1093, (2001) |
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| Prydz, Kristian; Simons, Kai |
| Cholesterol depletion reduces apical transport capacity in epithelial Madin-Darby canine kidney cells. |
| Biochem. J., 357, no. Pt 1, pp. 11-15, (2001) |
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| Lusa, Sari; Blom, Titta S.; Eskelinen, Eeva-Liisa; Kuismanen, Esa; MÃ¥nsson, Jan-Eric; Simons, Kai; Ikonen, Elina |
| Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane. |
| J. Cell. Sci., 114, no. Pt 10, pp. 1893-1900, (2001) |
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| Lafont, Frank; Simons, Kai |
| Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling. |
| Proc. Natl. Acad. Sci. U.S.A., 98, no. 6, pp. 3180-3184, (2001) |
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| Keller, Patrick; Toomre, Derek K; DÃaz, Elena; White, Jamie; Simons, Kai |
| Multicolour imaging of post-Golgi sorting and trafficking in live cells. |
| Nat. Cell Biol., 3, no. 2, pp. 140-149, (2001) |
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| Simons, Kai; Zerial, Marino |
| Traffic of Proteins and Compartmentalization of Eukaryotic Cells |
| Frontiers of Life, Volume II - Cells and Organisms, pp. 43-54, (2001) |
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| White, Jamie; Keller, Patrick; Stelzer, Ernst H K |
| Spatial partitioning of secretory cargo from Golgi resident proteins in live cells. |
| BMC Cell Biol., 2, pp. 19-19, (2001) |
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| 2000 |
| Simons, Kai; Ikonen, Elina |
| How cells handle cholesterol. |
| Science, 290, no. 5497, pp. 1721-1726, (2000) |
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| Simons, Kai; Gruenberg, Jean |
| Jamming the endosomal system: lipid rafts and lysosomal storage diseases. |
| Trends Cell Biol., 10, no. 11, pp. 459-462, (2000) |
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| Simons, Kai; Featherstone, Carol |
| EUROPEAN POLICY: Science in Europe. |
| Science, 290, no. 5494, pp. 1099-1101, (2000) |
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| Simons, Kai |
| A voice for European life scientists. An interview with Kai Simons, President of the European Life Science Organisation and Director of the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden. |
| EMBO Rep., 1, no. 5, pp. 381-383, (2000) |
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| Simons, Kai; Toomre, Derek K |
| Lipid rafts and signal transduction. |
| Nat. Rev. Mol. Cell Biol., 1, no. 1, pp. 31-39, (2000) |
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| Lecat, Sandra; Verkade, Paul; Thiele, Christoph; Fiedler, Klaus; Simons, Kai; Lafont, Frank |
| Different properties of two isoforms of annexin XIII in MDCK cells. |
| J. Cell. Sci., 113 ( Pt 14), pp. 2607-2618, (2000) |
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| Plant, Pamela J.; Lafont, Frank; Lecat, Sandra; Verkade, Paul; Simons, Kai; Rotin, Daniela |
| Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb. |
| J. Cell Biol., 149, no. 7, pp. 1473-1484, (2000) |
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| Toomre, Derek K; Steyer, Jürgen A.; Keller, Patrick; Almers, Wolfhard; Simons, Kai |
| Fusion of constitutive membrane traffic with the cell surface observed by evanescent wave microscopy. |
| J. Cell Biol., 149, no. 1, pp. 33-40, (2000) |
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| Pralle, A; Keller, Patrick; Florin, E L; Simons, Kai; Hörber, J K |
| Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells. |
| J. Cell Biol., 148, no. 5, pp. 997-1008, (2000) |
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| Bagnat, Michel; Keränen, Sirkka; Shevchenko, Anna; Shevchenko, Andrej; Simons, Kai |
| Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. |
| Proc. Natl. Acad. Sci. U.S.A., 97, no. 7, pp. 3254-3259, (2000) |
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| Benting, Jürgen; Lecat, Sandra; Zacchetti, Daniele; Simons, Kai |
| Protein expression in Drosophila Schneider cells. |
| Anal. Biochem., 278, no. 1, pp. 59-68, (2000) |
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| Verkade, Paul; Harder, Thomas; Lafont, Frank; Simons, Kai |
| Induction of caveolae in the apical plasma membrane of Madin-Darby canine kidney cells. |
| J. Cell Biol., 148, no. 4, pp. 727-739, (2000) |
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| 1999 |
| Benting, Jürgen; Rietveld, Anton; Ansorge, Iris; Simons, Kai |
| Acyl and alkyl chain length of GPI-anchors is critical for raft association in vitro. |
| FEBS Lett., 462, no. 1-2, pp. 47-50, (1999) |
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| Füllekrug, Joachim; Scheiffele, Peter; Simons, Kai |
| VIP36 localisation to the early secretory pathway. |
| J. Cell. Sci., 112 ( Pt 17), pp. 2813-2821, (1999) |
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| Benting, Jürgen; Rietveld, Anton; Simons, Kai |
| N-Glycans mediate the apical sorting of a GPI-anchored, raft-associated protein in Madin-Darby canine kidney cells. |
| J. Cell Biol., 146, no. 2, pp. 313-320, (1999) |
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| Cheong, Kwang Ho; Zacchetti, Daniele; Schneeberger, Eveline E.; Simons, Kai |
| VIP17/MAL, a lipid raft-associated protein, is involved in apical transport in MDCK cells. |
| Proc. Natl. Acad. Sci. U.S.A., 96, no. 11, pp. 6241-6248, (1999) |
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| Rietveld, Anton; Neutz, Stephanie; Simons, Kai; Eaton, Suzanne |
| Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains. |
| J. Biol. Chem., 274, no. 17, pp. 12049-12054, (1999) |
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| Lafont, Frank; Verkade, Paul; Galli, Thierry; Wimmer, Christian; Louvard, Daniel; Simons, Kai |
| Raft association of SNAP receptors acting in apical trafficking in Madin-Darby canine kidney cells. |
| Proc. Natl. Acad. Sci. U.S.A., 96, no. 7, pp. 3734-3738, (1999) |
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| Harder, Thomas; Simons, Kai |
| Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation. |
| Eur. J. Immunol., 29, no. 2, pp. 556-562, (1999) |
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| Scheiffele, Peter; Rietveld, Anton; Wilk, Thomas; Simons, Kai |
| Influenza viruses select ordered lipid domains during budding from the plasma membrane. |
| J. Biol. Chem., 274, no. 4, pp. 2038-2044, (1999) |
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| Scheiffele, Peter; Simons, Kai |
| Epithelial Polarity and Sorting |
| Epithelial morphogenesis in development and disease, chapt. 10, pp. 41-71, in: Cell adhesion and communication ; 7, (1999) |
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| 1998 |
| Rietveld, Anton; Simons, Kai |
| The differential miscibility of lipids as the basis for the formation of functional membrane rafts. |
| Biochim. Biophys. Acta, 1376, no. 3, pp. 467-479, (1998) |
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| Ikonen, Elina; Simons, Kai |
| Protein and lipid sorting from the trans-Golgi network to the plasma membrane in polarized cells. |
| Semin. Cell Dev. Biol., 9, no. 5, pp. 503-509, (1998) |
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| Lafont, Frank; Lecat, Sandra; Verkade, Paul; Simons, Kai |
| Annexin XIIIb associates with lipid microdomains to function in apical delivery. |
| J. Cell Biol., 142, no. 6, pp. 1413-1427, (1998) |
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| Lafont, Frank; Ikonen, Elina; Simons, Kai |
| Permeabilized Epithelial Cells to Study Exocytic Membrane Transport |
| Cell Biology: A Laboratory Handbook, 2nd Edition, Vol. 2, chapt. 4, pp. 229-238, (1998) |
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