| 2009 |
| Anna Katharina Sedello |
| Loss-of-Function screen for proteins cooperating with Runx1 in hematopoiesis and leukemogenesis |
| 2009 |
| Dragomir Krastev |
| An RNA interference synthetic interaction screen identifies vulnerability factors for TP53 mutant cells |
| 2009 |
| Frank Buchholz |
| Engineering DNA processing enzymes for the postgenomic era |
| Curr Opin Biotechnol, Vol. 20, no. 4, pp. 383-389, 2009 |
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| Marina Trouillas, Claire Saucourt, Bertrand Guillotin, Xavier Gauthereau, Li Ding, Frank Buchholz, Michael Xavier Doss, Agapios Sachinidis, Jurgen Hescheler, Oliver Hummel, Norbert Huebner, Raivo Kolde, Jaak Vilo, Herbert Schulz, Helene Boeuf |
| Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives |
| BMC Genomics, Vol. 10, pp. 73:1-73:20, 2009 |
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| Michael Buchert, Charbel Darido, Ebba Lagerqvist, Anna Sedello, Chantal Cazevieille, Frank Buchholz, Jean-Francois Bourgaux, Julie Pannequin, Dominique Joubert, Frederic Hollande |
| The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1 |
| Gastroenterology, Vol. 137, no. 1, pp. 156-164, 2009 |
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| Steffen Lawo, Mikhail Bashkurov, Michael Mullin, Mariana Gomez Ferreria, Ralf Kittler, Bianca Habermann, Andrea Tagliaferro, Ina Poser, James R A Hutchins, Bjorn Hegemann, Deborah Pinchev, Frank Buchholz, Jan-Michael Peters, Anthony A Hyman, Anne-Claude Gingras, Laurence Pelletier |
| HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity |
| Curr Biol, Vol. 19, no. 10, pp. 816-826, 2009 |
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| Li Ding, Maciej Paszkowski-Rogacz, Anja Nitzsche, Mikolaj Michal Slabicki, Anne-Kristin Heninger, Ingrid de Vries, Ralf Kittler, Magno Junqueira, Andrej Shevchenko, Herbert Schulz, Norbert Hubner, Michael Xavier Doss, Agapios Sachinidis, Juergen Hescheler, Roberto Iacone, Konstantinos Anastassiadis, A Francis Stewart, M Teresa Pisabarro, Antonio Caldarelli, Ina Poser, Mirko Theis, Frank Buchholz |
| A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity |
| Cell Stem Cell, Vol. 4, no. 5, pp. 403-415, 2009 |
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| Mirko Theis, Mikolaj Slabicki, Magno Junqueira, Maciej Paszkowski-Rogacz, Jana Sontheimer, Ralf Kittler, Anne-Kristine Heninger, Timo Glatter, Kristi Kruusmaa, Ina Poser, Anthony A Hyman, M Teresa Pisabarro, Matthias Gstaiger, Rudolf Aebersold, Andrej Shevchenko, Frank Buchholz |
| Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division |
| EMBO J., Vol. 28, no. 10, pp. 1453-1465, 2009 |
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| 2008 |
| Mikolaj Slabicki |
| A systematic investigation of DNA double strand break repair by a genome-wide RNAi screen in human cells (PhD-thesis) |
| 2008 |
| Ralf Kittler, Laurence Pelletier, Frank Buchholz |
| Systems biology of mammalian cell division |
| Cell Cycle, Vol. 7, no. 14, pp. 2123-2128, 2008 |
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| Ina Poser, Mihail Sarov, James R A Hutchins, Jean-Karim Heriche, Yusuke Toyoda, Andrei Pozniakovsky, Daniela Weigl, Anja Nitzsche, Bjorn Hegemann, Alexander W Bird, Laurence Pelletier, Ralf Kittler, Sujun Hua, Ronald Naumann, Martina Augsburg, Martina M Sykora, Helmut Hofemeister, Youming Zhang, Kim Nasmyth, Kevin P White, Steffen Dietzel, Karl Mechtler, Richard Durbin, A Francis Stewart, Jan-Michael Peters, Frank Buchholz, Anthony A Hyman |
| BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals |
| Nat. Methods, Vol. 5, no. 5, pp. 409-415, 2008 |
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| 2007 |
| Ralf Kittler, Vineeth Surendranath, Anne-Kristin Heninger, Mikolaj Slabicki, Mirko Theis, Gabriele Putz, Kristin Franke, Antonio Caldarelli, Hannes Grabner, Karol Kozak, Jan Wagner, Effi Rees, Bernd Korn, Corina Frenzel, Christoph Sachse, Birte Sonnichsen, Jie Guo, Janell Schelter, Julja Burchard, Peter S Linsley, Aimee L Jackson, Bianca Habermann, Frank Buchholz |
| Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies |
| Nat. Methods, Vol. 4, no. 4, pp. 337-344, 2007 |
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| Indrani Sarkar, Ilona Hauber, Joachim Hauber, Frank Buchholz |
| HIV-1 Proviral DNA Excision Using an Evolved Recombinase |
| Science, Vol. 316, no. 5833, pp. 1912-1915, 2007 |
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| Ralf Kittler, Laurence Pelletier, Anne-Kristine Heninger, Mikolaj Slabicki, Mirko Theis, Lukasz Miroslaw, Ina Poser, Steffen Lawo, Hannes Grabner, Karol Kozak, Jan Wagner, Vineeth Surendranath, Constance Richter, Wayne Bowen, Aimee L. Jackson, Bianca Habermann, Anthony A. Hyman, Frank Buchholz |
| Genome-scale RNAi profiling of cell division in human tissue culture cells |
| Nat. Cell. Biol., Vol. 9, no. 12, pp. 1401-1412, 2007 |
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| Juraj Gregan, Christian G. Riedel, Mark Petronczki, Lubos Cipak, Cornelia Rumpf, Ina Poser, Frank Buchholz, Karl Mechtler, Kim Nasmyth |
| Tandem affinity purification of functional TAP-tagged proteins from human cells |
| Nat Protoc, Vol. 2, no. 5, pp. 1145-1151, 2007 |
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| Jorg Cammenga, Birte Niebuhr, Stefan Horn, Ulla Bergholz, Gabriele Putz, Frank Buchholz, Jurgen Lohler, Carol Stocking |
| RUNX1 DNA-Binding Mutants, Associated with Minimally Differentiated Acute Myelogenous Leukemia, Disrupt Myeloid Differentiation |
| Cancer Res., Vol. 67, no. 2, pp. 537-545, 2007 |
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| 2006 |
| Ina Poser, Frank Buchholz |
| A new approach to specify RNAi experiments |
| European Pharmaceutical Review, Vol. 3, pp. 12-17, 2006 |
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| Christian G Riedel, Vittorio L Katis, Yuki Katou, Saori Mori, Takehiko Itoh, Wolfgang Helmhart, Marta Galova, Mark Petronczki, Juraj Gregan, Bulent Cetin, Ingrid Mudrak, Egon Ogris, Karl Mechtler, Laurence Pelletier, Frank Buchholz, Katsuhiko Shirahige, Kim Nasmyth |
| Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I |
| Nature, Vol. 441, no. 7089, pp. 53-61, 2006 |
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| Ralf Kittler |
| Functional genomic analysis of cell cycle progression in human tissue culture cells (Phd-thesis) |
| 2006 |
| Christophe J Echeverri, Philip A Beachy, Buzz Baum, Michael Boutros, Frank Buchholz, Sumit K Chanda, Julian Downward, Jan Ellenberg, Andrew G Fraser, Nir Hacohen, William C Hahn, Aimee L Jackson, Amy Kiger, Peter S Linsley, Lawrence Lum, Yong Ma, Bernard Mathey-Prevot, David E Root, David M Sabatini, Jussi Taipale, Norbert Perrimon, Rene Bernards |
| Minimizing the risk of reporting false positives in large-scale RNAi screens |
| Nat. Methods, Vol. 3, no. 10, pp. 777-779, 2006 |
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| Li Ding, Frank Buchholz |
| RNAi in embryonic stem cells |
| Stem Cell Rev, Vol. 2, no. 1, pp. 11-18, 2006 |
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| Frank Buchholz, Ralf Kittler, Mikolaj Slabicki, Mirko Theis |
| Enzymatically prepared RNAi libraries |
| Nat. Methods, Vol. 3, no. 9, pp. 696-700, 2006 |
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| Gabriele Putz, Andrea Rosner, Ina Nuesslein, Nicole Schmitz, Frank Buchholz |
| AML1 deletion in adult mice causes splenomegaly and lymphomas |
| Oncogene, Vol. 25, no. 6, pp. 929-939, 2006 |
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| 2005 |
| Ralf Kittler, Laurence Pelletier, Chunling Ma, Ina Poser, Steffi Fischer, Anthony A Hyman, Frank Buchholz |
| RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells |
| Proc. Natl. Acad. Sci. U.S.A., Vol. 102, no. 7, pp. 2396-2401, 2005 |
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| Frank Buchholz |
| RNA-Interference in mammalian cells |
| European Biotechnology Newsletter, Vol. 4, pp. 39-42, 2005 |
| Frank Buchholz |
| Functional Genomics in Mammalian Cells by RNAi: Opportunities and Challenges |
| Laborwelt, Vol. 6, no. 2, pp. 18-21, 2005 |
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| Eberhard Krauß, Anne-Kristin Heninger, Ralf Kittler, Annett Lohmann, Ina Poser, Jan Wagner, Kristin Franke, Karol Kozak, Hannes Grabner, Frank Buchholz |
| Eine Genom-weite RNA-Interferenz-Bibliothek für die funktionelle Charakterisierung aller Gene in kultivierten, menschlichen Zellen |
| BIOspektrum, Vol. 11, no. 4, pp. 436-440, 2005 |
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| Ralf Kittler, Frank Buchholz |
| Functional genomic analysis of cell division by endoribonuclease-prepared siRNAs. |
| Cell Cycle, Vol. 4, no. 4, pp. 564-567, 2005 |
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| Ralf Kittler, Anne-Kristin Heninger, Kristin Franke, Bianca Habermann, Frank Buchholz |
| Production of endoribonuclease-prepared short interfering RNAs for gene silencing in mammalian cells. |
| Nat. Methods, Vol. 2, no. 10, pp. 779-784, 2005 |
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| Lukasz Miroslaw, Artur Chorazyczewski, Frank Buchholz, Ralf Kittler |
| Correlation-based Method for Automatic Mitotic Cell Detection in Phase Contrast Microscopy |
| Computer Recognition Systems : Proceedings of 4th International Conference on Computer Recognition Systems CORES '05, Springer, Berlin, Chapt. IV, pp. 627-634, 2005 |
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| Dong Ji Zhang, Qi Wang, Jie Wei, Gyulnar Baimukanova, Frank Buchholz, A Francis Stewart, Xiaohong Mao, Nigel Killeen |
| Selective expression of the cre recombinase in late-stage thymocytes using the distal promoter of the lck gene. |
| J. Immunol., Vol. 174, no. 11, pp. 6725-6731, 2005 |
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| Frank Buchholz, David Drechsel, Martine Ruer, Ralf Kittler |
| Production of siRNA in vitro by enzymatic digestion of double-stranded RNA |
| Gene Silencing by RNA Interference : Technology and Application, CRC Press, Boca Raton, Florida, Chapt. 6, pp. 87-99, 2005 |
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| Frank Buchholz, Federico Calegari, Ralf Kittler, Wieland B. Huttner |
| RNA interference in postimplantation mouse embryos |
| RNA interference technology: from basic science to drug development, Cambridge University Press, Cambridge, Chapt. 15, pp. 207-219, 2005 |
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| 2004 |
| Effi Rees, Bernhard Korn, Frank Buchholz |
| Genfunktionsanalyse im Genom-weiten Maßstab mit 'small interfering' RNAs |
| Laborwelt, Vol. 5, no. 1, pp. 21-22, 2004 |
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| Ralf Kittler, Gabriele Putz, Laurence Pelletier, Ina Poser, Anne-Kristin Heninger, David Drechsel, Steffi Fischer, Irena Konstantinova, Bianca Habermann, Hannes Grabner, Marie-Laure Yaspo, Heinz Himmelbauer, Bernd Korn, Karla Neugebauer, Maria Teresa Pisabarro, Frank Buchholz |
| An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division |
| Nature, Vol. 432, no. 7020, pp. 1036-1040, 2004 |
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| Andreas Henschel, Frank Buchholz, Bianca Habermann |
| DEQOR: a web-based tool for the design and quality control of siRNAs |
| Nucleic Acids Res., Vol. 32, no. Web Server issue, pp. W113-W120, 2004 |
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| Jan Kronke, Ralf Kittler, Frank Buchholz, Marc P Windisch, Thomas Pietschmann, Ralf Bartenschlager, Michael Frese |
| Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. |
| J. Virol., Vol. 78, no. 7, pp. 3436-3446, 2004 |
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| Federico Calegari, Anne-Marie Marzesco, Ralf Kittler, Frank Buchholz, Wieland B Huttner |
| Tissue-specific RNA interference in post-implantation mouse embryos using directional electroporation and whole embryo culture |
| Differentiation, Vol. 72, no. 2-3, pp. 92-102, 2004 |
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| 2003 |
| Eric Ennifar, Joachim E W Meyer, Frank Buchholz, A Francis Stewart, Dietrich Suck |
| Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation |
| Nucleic Acids Res., Vol. 31, no. 18, pp. 5449-5460, 2003 |
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| Ralf Kittler, Frank Buchholz |
| RNA interference: gene silencing in the fast lane. |
| Semin. Cancer Biol., Vol. 13, no. 4, pp. 259-265, 2003 |
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| 2002 |
| D. R. Shimshek, J. Kim, M. R. Hubner, D. J. Spergel, Frank Buchholz, E. Casanova, A. Francis Stewart, P. H. Seeburg, R. Sprengel |
| Codon-improved Cre recombinase (iCre) expression in the mouse. |
| Genesis, Vol. 32, no. 1, pp. 19-26, 2002 |
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| Dun Yang, Frank Buchholz, Zhongdong Huang, Andrei Goga, Chih-Ying Chen, Frances M. Brodsky, J. Michael Bishop |
| Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. |
| Proc. Natl. Acad. Sci. U.S.A., Vol. 99, no. 15, pp. 9942-9947, 2002 |
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| Federico Calegari, Wulf Haubensak, Dun Yang, Wieland B. Huttner, Frank Buchholz |
| Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA. |
| Proc. Natl. Acad. Sci. U.S.A., Vol. 99, no. 22, pp. 14236-14240, 2002 |
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