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Anthony Hyman

Publications

2010
Jaensch, Steffen; Decker, Markus; Hyman, Anthony A.; Myers, Eugene
Automated tracking and analysis of centrosomes in early Caenorhabditis elegans embryos
Bioinformatics, 26, no. 12, pp. 13-20, (2010)
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Greenan, Garrett
Setting mitotic spindle length in the early Caenorhabditis elegans embryo
[Doctoral Thesis] Technische Universität Dresden, (2010)
Goehring, Nathan W.; Chowdhury, Debanjan; Hyman, Anthony A.; Grill, Stephan W.
FRAP analysis of membrane-associated proteins: lateral diffusion and membrane-cytoplasmic exchange
Biophys. J., pp. 1-1, (2010)
2009
Howard, Jonathon; Hyman, Anthony A.
Growth, fluctuation and switching at microtubule plus ends.
Nat. Rev. Mol. Cell Biol., 10, no. 8, pp. 569-574, (2009)
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Brangwynne, Clifford; Eckmann, Christian R.; Courson, David S; Rybarska, Agata; Hoege, Carsten; Gharakhani, Joebin; Jülicher, Frank; Hyman, Anthony A.
Germline P granules are liquid droplets that localize by controlled dissolution/condensation.
Science, 324, no. 5935, pp. 1729-1732, (2009)
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Lawo, Steffen; Bashkurov, Mikhail; Mullin, Michael; Ferreria, Mariana Gomez; Kittler, Ralf; Habermann, Bianca; Tagliaferro, Andrea; Poser, Ina; Hutchins, James R A; Hegemann, Björn; Pinchev, Deborah; Buchholz, Frank; Peters, Jan-Michael; Hyman, Anthony A.; Gingras, Anne-Claude; Pelletier, Laurence
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.
Curr. Biol., 19, no. 10, pp. 816-826, (2009)
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Redemann, Stefanie
The role of the acto-myosin cortex for force-generation and spindle positioning in the C. elegans embryo
[Doctoral Thesis] Technische Universität Dresden, (2009)
Zanic, Marija; Stear, Jeffrey H.; Howard, Jonathon; Hyman, Anthony A.
EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.
PLoS ONE, 4, no. 10, pp. 7585-7585, (2009)
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2008
Petrásek, Zdenek; Hoege, Carsten; Mashaghi, Alireza; Ohrt, Thomas; Hyman, Anthony A.; Schwille, Petra
Characterization of protein dynamics in asymmetric cell division by scanning fluorescence correlation spectroscopy.
Biophys. J., 95, no. 11, pp. 5476-5486, (2008)
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Mouysset, Julien; Deichsel, Alexandra; Moser, Sandra; Hoege, Carsten; Hyman, Anthony A.; Gartner, Anton; Hoppe, Thorsten
Cell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication.
Proc. Natl. Acad. Sci. U.S.A., 105, no. 35, pp. 12879-12884, (2008)
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Boxem, Mike; Maliga, Zoltan; Klitgord, Niels; Li, Na; Lemmens, Irma; Mana, Miyeko; Lichtervelde, Lorenzo de; Mul, Joram D.; Peut, Diederik van de; Devos, Maxime; Simonis, Nicolas; Yildirim, Muhammed A.; Cokol, Murat; Kao, Huey-Ling; Smet, Anne-Sophie de; Schlaitz, Anne-Lore; Wang, Haidong; Hao, Tong; Milstein, Stuart; Fan, Changyu; Tipsword, Mike; Drew, Kevin; Galli, Matilde; Rhrissorrakrai, Kahn; Drechsel, David N.; Koller, Daphne; Roth, Frederick P.; Iakoucheva, Lilia M.; Dunker, A. Keith; Bonneau, Richard; Gunsalus, Kristin C.; Hill, David E.; Piano, Fabio; Tavernier, Jan; Heuvel, Sander van den; Hyman, Anthony A.; Vidal, Marc
A protein domain-based interactome network for C. elegans early embryogenesis.
Cell, 134, no. 3, pp. 534-545, (2008)
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Bird, Alexander W.; Hyman, Anthony A.
Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A.
J. Cell Biol., 182, no. 2, pp. 289-300, (2008)
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Poser, Ina; Sarov, Mihail; Hutchins, James R A; Hériché, Jean-Karim; Toyoda, Yusuke; Pozniakovsky, Andrei I.; Weigl, Daniela; Nitzsche, Anja; Hegemann, Björn; Bird, Alexander W.; Pelletier, Laurence; Kittler, Ralf; Hua, Sujun; Naumann, Ronald; Augsburg, Martina; Sykora, Martina M; Hofemeister, Helmut; Zhang, Youming; Nasmyth, Kim; White, Kevin P; Dietzel, Steffen; Mechtler, Karl; Durbin, Richard; Stewart, A. Francis; Peters, Jan-Michael; Buchholz, Frank; Hyman, Anthony A.
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.
Nat. Methods, 5, no. 5, pp. 409-415, (2008)
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Brouhard, Gary J.; Stear, Jeffrey H.; Noetzel, Tim L.; Al-Bassam, Jawdat; Kinoshita, Kazuhisa; Harrison, Stephen C.; Howard, Jonathon; Hyman, Anthony A.
XMAP215 is a processive microtubule polymerase.
Cell, 132, no. 1, pp. 79-88, (2008)
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Zhu, Fei; Lawo, Steffen; Bird, Alexander W.; Pinchev, Deborah; Ralph, Alison; Richter, Constance; Müller-Reichert, Thomas; Kittler, Ralf; Hyman, Anthony A.; Pelletier, Laurence
The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis.
Curr. Biol., 18, no. 2, pp. 136-141, (2008)
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Green, Rebecca A.; Audhya, Anjon; Pozniakovsky, Andrei I.; Dammermann, Alexander; Pemble, Hayley; Monen, Joost; Portier, Nathan; Hyman, Anthony A.; Desai, Arshad; Oegema, Karen
Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo
Fluorescent Proteins, chapt. 9, pp. 179-218, in: Methods in cell biology, 85, (2008)
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Lundin, Victor F; Srayko, Martin; Hyman, Anthony A.; Leroux, Michel R
Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans.
Dev. Biol., 313, no. 1, pp. 320-334, (2008)
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2007
Elie-Caille, Céline; Severin, Fedor F.; Helenius, Jonne H.; Howard, Jonathon; Müller, Daniel J. ; Hyman, Anthony A.
Straight GDP-tubulin protofilaments form in the presence of taxol.
Curr. Biol., 17, no. 20, pp. 1765-1770, (2007)
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Schonegg, Stephanie; Constantinescu, Alexandru T.; Hoege, Carsten; Hyman, Anthony A.
The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos.
Proc. Natl. Acad. Sci. U.S.A., 104, no. 38, pp. 14976-14981, (2007)
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Nieland, Thomas J. F.; Shaw, Jared T; Jaipuri, Firoz A; Maliga, Zoltan; Duffner, Jay L; Koehler, Angela N; Krieger, Monty
Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.
J. Lipid Res., 48, no. 8, pp. 1832-1845, (2007)
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Stirling, Peter C; Srayko, Martin; Takhar, Karam S; Pozniakovsky, Andrei I.; Hyman, Anthony A.; Leroux, Michel R
Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression.
Mol. Biol. Cell, 18, no. 6, pp. 2336-2345, (2007)
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Al-Bassam, Jawdat; Larsen, Nicholas A.; Hyman, Anthony A.; Harrison, Stephen C.
Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding.
Structure, 15, no. 3, pp. 355-362, (2007)
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Cowan, Carrie R.; Hyman, Anthony A.
Acto-myosin reorganization and PAR polarity in C. elegans.
Development, 134, no. 6, pp. 1035-1043, (2007)
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Howard, Jonathon; Hyman, Anthony A.
Microtubule polymerases and depolymerases.
Curr. Opin. Cell Biol., 19, no. 1, pp. 31-35, (2007)
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Mori, Daisuke; Yano, Yoshihisa; Toyo-oka, Kazuhito; Yoshida, Noriyuki; Yamada, Masami; Muramatsu, Masami; Zhang, Dongwei; Saya, Hideyuki; Toyoshima, Yoko Y; Kinoshita, Kazuhisa; Wynshaw-Boris, Anthony; Hirotsune, Shinji
NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment.
Mol. Cell. Biol., 27, no. 1, pp. 352-367, (2007)
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Cisneros, David A.
Molecular assemblies observed by atomic force microscopy
[Doctoral Thesis] Technische Universität Dresden, (2007)
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Said, Amani
Mechanisms underlying cell sorting at the A-P compartment boundary in the Drosophila wing
[Doctoral Thesis] Technische Universität Dresden, (2007)
Bringmann, Henrik; Cowan, Carrie R.; Kong, Jun; Hyman, Anthony A.
LET-99, GOA-1/GPA-16, and GPR-1/2 are required for aster-positioned cytokinesis.
Curr. Biol., 17, no. 2, pp. 185-191, (2007)
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Bringmann, Henrik
Experiments concerning the mechanisms of cytokinesis in Caenorhabditis elegans embryos
[Doctoral Thesis] Technische Universität Dresden, (2007)
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2006
Cowan, Carrie R.; Hyman, Anthony A.
Cyclin E-Cdk2 temporally regulates centrosome assembly and establishment of polarity in Caenorhabditis elegans embryos.
Nat. Cell Biol., 8, no. 12, pp. 1441-1447, (2006)
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Sandall, Sharsti; Severin, Fedor F.; McLeod, Ian X.; Yates, John R.; Oegema, Karen; Hyman, Anthony A.; Desai, Arshad
A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension.
Cell, 127, no. 6, pp. 1179-1191, (2006)
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Pecreaux, Jacques; Röper, Jens-Christian; Kruse, Karsten; Jülicher, Frank; Hyman, Anthony A.; Grill, Stephan W.; Howard, Jonathon
Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators.
Curr. Biol., 16, no. 21, pp. 2111-2122, (2006)
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Pelletier, Laurence; O'Toole, Eileen T.; Schwager, Anne; Hyman, Anthony A.; Müller-Reichert, Thomas
Centriole assembly in Caenorhabditis elegans.
Nature, 444, no. 7119, pp. 619-623, (2006)
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Sarov, Mihail; Schneider, Susan; Pozniakovsky, Andrei I.; Roguev, Assen; Ernst, Susanne; Zhang, Youming; Hyman, Anthony A.; Stewart, A. Francis
A recombineering pipeline for functional genomics applied to Caenorhabditis elegans.
Nat. Methods, 3, no. 10, pp. 839-844, (2006)
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Varga, Vladimir; Helenius, Jonne H.; Tanaka, Kozo; Hyman, Anthony A.; Tanaka, Tomoyuki U; Howard, Jonathon
Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner.
Nat. Cell Biol., 8, no. 9, pp. 957-962, (2006)
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Schonegg, Stephanie; Hyman, Anthony A.
CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos.
Development, 133, no. 18, pp. 3507-3516, (2006)
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Kerssemakers, Jacob W. J.; Munteanu, Emilia-Laura; Laan, Liedewij; Noetzel, Tim L.; Janson, Marcel E; Dogterom, Marileen
Assembly dynamics of microtubules at molecular resolution.
Nature, 442, no. 7103, pp. 709-712, (2006)
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Benenati, Gaspare
Osmotic balance and establishment of polarity in the C. elegans embryo require cytochrome P450 CYP31A
[Doctoral Thesis] Technische Universität Dresden, (2006)
Al-Bassam, Jawdat; Breugel, Mark van; Harrison, Stephen C.; Hyman, Anthony A.
Stu2p binds tubulin and undergoes an open-to-closed conformational change.
J. Cell Biol., 172, no. 7, pp. 1009-1022, (2006)
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Dinu, Cerasela Z.
Leveraging the motor protein kinesin to manipulate DNA molecules in synthetic environment
[Doctoral Thesis] Technische Universität Dresden, (2006)
Sokolov, Svyatoslav; Knorre, Dmitry A.; Smirnova, Ekaterina; Markova, Olga V.; Pozniakovsky, Andrei I.; Skulachev, Vladimir P.; Severin, Fedor F.
Ysp2 mediates death of yeast induced by amiodarone or intracellular acidification.
Biochim. Biophys. Acta, 1757, no. 9-10, pp. 1366-1370, (2006)
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Kinoshita, Kazuhisa; Noetzel, Tim L.; Arnal, Isabelle; Drechsel, David N.; Hyman, Anthony A.
Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1.
J. Muscle Res. Cell. Motil., 27, no. 2, pp. 107-114, (2006)
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Sokolov, Svyatoslav; Pozniakovsky, Andrei I.; Bocharova, Natalia; Knorre, Dmitry A.; Severin, Fedor F.
Expression of an expanded polyglutamine domain in yeast causes death with apoptotic markers.
Biochim. Biophys. Acta, 1757, no. 5-6, pp. 660-666, (2006)
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Sapra, K. Tanuj; Besir, Hüseyin; Oesterhelt, Dieter; Müller, Daniel J.
Characterizing molecular interactions in different bacteriorhodopsin assemblies by single-molecule force spectroscopy.
J. Mol. Biol., 355, no. 4, pp. 640-650, (2006)
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2005
Bringmann, Henrik
Cytokinesis and the spindle midzone.
Cell Cycle, 4, no. 12, pp. 1709-1712, (2005)
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Schonegg, Stephanie
Rho GTPase family members in establishment of polarity in C.elegans embryos
[Doctoral Thesis] Technische Universität Dresden, (2005)
Kinoshita, Kazuhisa; Noetzel, Tim L.; Pelletier, Laurence; Mechtler, Karl; Drechsel, David N.; Schwager, Anne; Lee, Mike; Raff, Jordan W; Hyman, Anthony A.
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis.
J. Cell Biol., 170, no. 7, pp. 1047-1055, (2005)
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Barros, Teresa P.; Kinoshita, Kazuhisa; Hyman, Anthony A.; Raff, Jordan W
Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules.
J. Cell Biol., 170, no. 7, pp. 1039-1046, (2005)
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Gunsalus, Kristin C.; Ge, Hui; Schetter, Aaron J; Goldberg, Debra S; Han, Jing-Dong J; Hao, Tong; Berriz, Gabriel F; Bertin, Nicolas; Huang, Jerry; Chuang, Ling-Shiang; Li, Ning; Mani, Ramamurthy; Hyman, Anthony A.; Sönnichsen, Birte; Echeverri, Christophe J.; Roth, Frederick P.; Vidal, Marc; Piano, Fabio
Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis.
Nature, 436, no. 7052, pp. 861-865, (2005)
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Srayko, Martin; Kaya, Aynur; Stamford, Joanne; Hyman, Anthony A.
Identification and characterization of factors required for microtubule growth and nucleation in the early C. elegans embryo.
Dev. Cell, 9, no. 2, pp. 223-236, (2005)
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Ozlü, Nurhan; Srayko, Martin; Kinoshita, Kazuhisa; Habermann, Bianca; O'Toole, Eileen T.; Müller-Reichert, Thomas; Schmalz, Natalie; Desai, Arshad; Hyman, Anthony A.
An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles.
Dev. Cell, 9, no. 2, pp. 237-248, (2005)
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Bringmann, Henrik; Hyman, Anthony A.
A cytokinesis furrow is positioned by two consecutive signals.
Nature, 436, no. 7051, pp. 731-734, (2005)
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Kurz, Thimo; Ozlü, Nurhan; Rudolf, Fabian; O'Rourke, Sean M; Luke, Brian; Hofmann, Kay; Hyman, Anthony A.; Bowerman, Bruce; Peter, Matthias
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.
Nature, 435, no. 7046, pp. 1257-1261, (2005)
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Grill, Stephan W.; Hyman, Anthony A.
Spindle positioning by cortical pulling forces.
Dev. Cell, 8, no. 4, pp. 461-465, (2005)
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Tanaka, Kozo; Mukae, Naomi; Dewar, Hilary; Breugel, Mark van; James, Euan K; Prescott, Alan R; Antony, Claude; Tanaka, Tomoyuki U
Molecular mechanisms of kinetochore capture by spindle microtubules.
Nature, 434, no. 7036, pp. 987-994, (2005)
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Sönnichsen, Birte; Koski, L B; Walsh, A; Marschall, P; Neumann, B; Brehm, Michael; Alleaume, Anne-Marie; Artelt, J.; Bettencourt, P; Cassin, E; Hewitson, M; Holz, Christian; Khan, M; Lazik, S; Martin, Claudia; Nitzsche, Bert; Ruer, Martine; Stamford, Joanne; Winzi, M; Heinkel, R; Röder, M; Finell, J; Häntsch, H; Jones, S J M; Jones, M; Piano, Fabio; Gunsalus, Kristin C.; Oegema, Karen; Gönczy, Pierre; Coulson, A; Hyman, Anthony A.; Echeverri, C J
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans.
Nature, 434, no. 7032, pp. 462-469, (2005)
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Hyman, Anthony A.
Boveri revisited.
EMBO J., 24, no. 6, pp. 1104-1110, (2005)
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Noetzel, Tim L.; Drechsel, David N.; Hyman, Anthony A.; Kinoshita, Kazuhisa
A comparison of the ability of XMAP215 and tau to inhibit the microtubule destabilizing activity of XKCM1.
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 360, no. 1455, pp. 591-594, (2005)
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Kittler, Ralf; Pelletier, Laurence; Ma, Chunling; Poser, Ina; Fischer, Steffi; Hyman, Anthony A.; Buchholz, Frank
RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells.
Proc. Natl. Acad. Sci. U.S.A., 102, no. 7, pp. 2396-2401, (2005)
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Pozniakovsky, Andrei I.; Knorre, Dmitry A.; Markova, Olga V.; Hyman, Anthony A.; Skulachev, Vladimir P.; Severin, Fedor F.
Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast.
J. Cell Biol., 168, no. 2, pp. 257-269, (2005)
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Kovalchuk, Andriy
Molecular analysis of the LTR Retrotransposon Ylt1 from the genome of dimorphic fungus yarrowia lipolytica
[Doctoral Thesis] Technische Universität Dresden, (2005)
Hyman, Anthony A.; Howard, Jonathon
Cell structure and dynamics
Curr. Opin. Cell Biol., 17, pp. 1-2, (2005)
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2004
Hess, Henry; Röper, Jens-Christian; Grill, Stephan W.; Koelle, Michael R
RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans.
Cell, 119, no. 2, pp. 209-218, (2004)
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Cowan, Carrie R.; Hyman, Anthony A.
Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos.
Nature, 431, no. 7004, pp. 92-96, (2004)
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Sampath, Srinath; Ohi, Ryoma; Leismann, Oliver; Salic, Adrian; Pozniakovsky, Andrei I.; Funabiki, Hironori
The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly.
Cell, 118, no. 2, pp. 187-202, (2004)
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Pelletier, Laurence; Ozlü, Nurhan; Hannak, Eva; Cowan, Carrie R.; Habermann, Bianca; Ruer, Martine; Müller-Reichert, Thomas; Hyman, Anthony A.
The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication.
Curr. Biol., 14, no. 10, pp. 863-873, (2004)
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Bringmann, Henrik; Skiniotis, Georgios; Spilker, Annina; Kandels-Lewis, Stefanie; Vernos, Isabelle; Surrey, Thomas
A kinesin-like motor inhibits microtubule dynamic instability.
Science, 303, no. 5663, pp. 1519-1522, (2004)
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Schaar, Bruce T; Kinoshita, Kazuhisa; McConnell, Susan K
Doublecortin microtubule affinity is regulated by a balance of kinase and phosphatase activity at the leading edge of migrating neurons.
Neuron, 41, no. 2, pp. 203-213, (2004)
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Cowan, Carrie R.; Hyman, Anthony A.
Asymmetric cell division in C. elegans: cortical polarity and spindle positioning.
Annu. Rev. Cell Dev. Biol., 20, pp. 427-453, (2004)
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2003
Quintin, Sophie; Mains, Paul E; Zinke, Andrea; Hyman, Anthony A.
The mbk-2 kinase is required for inactivation of MEI-1/katanin in the one-cell Caenorhabditis elegans embryo.
EMBO Rep., 4, no. 12, pp. 1175-1181, (2003)
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O'Toole, Eileen T.; McDonald, Kent; Mäntler, Jana; McIntosh, J. Richard; Hyman, Anthony A.; Müller-Reichert, Thomas
Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans.
J. Cell Biol., 163, no. 3, pp. 451-456, (2003)
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Srayko, Martin; Quintin, Sophie; Schwager, Anne; Hyman, Anthony A.
Caenorhabditis elegans TAC-1 and ZYG-9 form a complex that is essential for long astral and spindle microtubules.
Curr. Biol., 13, no. 17, pp. 1506-1511, (2003)
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Breugel, Mark van; Drechsel, David N.; Hyman, Anthony A.
Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family of microtubule-associated proteins is a plus end-binding microtubule destabilizer.
J. Cell Biol., 161, no. 2, pp. 359-369, (2003)
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Howard, Jonathon; Hyman, Anthony A.
Dynamics and mechanics of the microtubule plus end.
Nature, 422, no. 6933, pp. 753-758, (2003)
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Müller-Reichert, Thomas; Sassoon, Ingrid; O'Toole, Eileen T.; Romao, Maryse; Ashford, Anthony J.; Hyman, Anthony A.; Antony, Claude
Analysis of the distribution of the kinetochore protein Ndc10p in Saccharomyces cerevisiae using 3-D modeling of mitotic spindles.
Chromosoma, 111, no. 7, pp. 417-428, (2003)
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Kirkham, Matthew; Müller-Reichert, Thomas; Oegema, Karen; Grill, Stephan W.; Hyman, Anthony A.
SAS-4 is a C. elegans centriolar protein that controls centrosome size.
Cell, 112, no. 4, pp. 575-587, (2003)
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2002
Mendoza, Manuel; Hyman, Anthony A.; Glotzer, Michael
GTP binding induces filament assembly of a recombinant septin.
Curr. Biol., 12, no. 21, pp. 1858-1863, (2002)
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Kaitna, Susanne; Schnabel, Heinke; Schnabel, Ralf; Hyman, Anthony A.; Glotzer, Michael
A ubiquitin C-terminal hydrolase is required to maintain osmotic balance and execute actin-dependent processes in the early C. elegans embryo.
J. Cell. Sci., 115, no. Pt 11, pp. 2293-2302, (2002)
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Hannak, Eva; Oegema, Karen; Kirkham, Matthew; Gönczy, Pierre; Habermann, Bianca; Hyman, Anthony A.
The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent.
J. Cell Biol., 157, no. 4, pp. 591-602, (2002)
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2001
Hannak, Eva; Kirkham, Matthew; Hyman, Anthony A.; Oegema, Karen
Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans.
J. Cell Biol., 155, no. 7, pp. 1109-1116, (2001)
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Gönczy, Pierre; Bellanger, Jean-Michel; Kirkham, Matthew; Pozniakovsky, Andrei I.; Baumer, Karine; Phillips, Jennifer B.; Hyman, Anthony A.
zyg-8, a gene required for spindle positioning in C. elegans, encodes a doublecortin-related kinase that promotes microtubule assembly.
Dev. Cell, 1, no. 3, pp. 363-375, (2001)
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Oegema, Karen; Desai, Arshad; Rybina, Sonja; Kirkham, Matthew; Hyman, Anthony A.
Functional analysis of kinetochore assembly in Caenorhabditis elegans.
J. Cell Biol., 153, no. 6, pp. 1209-1226, (2001)
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Popov, Andrei V.; Pozniakovsky, Andrei I.; Arnal, Isabelle; Antony, Claude; Ashford, Anthony J.; Kinoshita, Kazuhisa; Tournebize, Regis; Hyman, Anthony A.; Karsenti, Eric
XMAP215 regulates microtubule dynamics through two distinct domains.
EMBO J., 20, no. 3, pp. 397-410, (2001)
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Grill, Stephan W.; Gönczy, Pierre; Stelzer, Ernst H K; Hyman, Anthony A.
Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo.
Nature, 409, no. 6820, pp. 630-633, (2001)
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Wittmann, Torsten; Hyman, Anthony A.; Desai, Arshad
The spindle: a dynamic assembly of microtubules and motors.
Nat. Cell Biol., 3, no. 1, pp. 28-34, (2001)
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Gönczy, Pierre; Grill, Stephan W.; Stelzer, Ernst H K; Kirkham, Matthew; Hyman, Anthony A.
Spindle positioning during the asymmetric first cell division of Caenorhabditis elegans embryos.
Novartis Found. Symp., 237, pp. 164-175, (2001)
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Nielsen, Erik; Severin, Fedor F.; Hyman, Anthony A.; Zerial, Marino
In vitro reconstitution of endosome motility along microtubules
Kinesin protocols, chapt. 12, pp. 133-146, in: Methods in molecular biology ; 164, (2001)
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2000
Gönczy, Pierre; Echeverri, Christophe J.; Oegema, Karen; Coulson, A; Jones, Steven J. M.; Copley, Richard R.; Duperon, John; Oegema, Jeffrey; Brehm, Michael; Cassin, E; Hannak, Eva; Kirkham, Matthew; Pichler, Silke; Flohrs, Kathrin; Goessen, A; Leidel, Sebastian; Alleaume, Anne-Marie; Martin, Cecilie; Ozlü, Nurhan; Bork, Peer; Hyman, Anthony A.
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III.
Nature, 408, no. 6810, pp. 331-336, (2000)
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Jantsch-Plunger, V; Gönczy, Pierre; Romano, Alper; Schnabel, Heinke; Hamill, Danielle; Schnabel, Ralf; Hyman, Anthony A.; Glotzer, Michael
CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis.
J. Cell Biol., 149, no. 7, pp. 1391-1404, (2000)
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Arnal, Isabelle; Karsenti, Eric; Hyman, Anthony A.
Structural transitions at microtubule ends correlate with their dynamic properties in Xenopus egg extracts.
J. Cell Biol., 149, no. 4, pp. 767-774, (2000)
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Pichler, Silke; Gönczy, Pierre; Schnabel, Heinke; Pozniakovsky, Andrei I.; Ashford, Anthony J.; Schnabel, Ralf; Hyman, Anthony A.
OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos.
Development, 127, no. 10, pp. 2063-2073, (2000)
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Ahmad, F. J.; Hughey, Jessica; Wittmann, Torsten; Hyman, Anthony A.; Greaser, Marion; Baas, Peter W.
Motor proteins regulate force interactions between microtubules and microfilaments in the axon.
Nat. Cell Biol., 2, no. 5, pp. 276-280, (2000)
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Hyman, Anthony A.
Centrosomes: Sic transit gloria centri.
Curr. Biol., 10, no. 7, pp. 276-278, (2000)
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1999
Gönczy, Pierre; Pichler, Silke; Kirkham, Matthew; Hyman, Anthony A.
Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo.
J. Cell Biol., 147, no. 1, pp. 135-150, (1999)
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Desai, Arshad; Hyman, Anthony A.
Microtubule cytoskeleton: No longer an also Ran.
Curr. Biol., 9, no. 18, pp. 704-707, (1999)
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Gönczy, Pierre; Schnabel, Heinke; Kaletta, Titus; Amores, Ana Duran; Hyman, Anthony A.; Schnabel, Ralf
Dissection of cell division processes in the one cell stage Caenorhabditis elegans embryo by mutational analysis.
J. Cell Biol., 144, no. 5, pp. 927-946, (1999)
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Wittmann, Torsten; Hyman, Anthony A.
Recombinant p50/dynamitin as a tool to examine the role of dynactin in intracellular processes
Mitosis and meiosis, pp. 137-143, in: Methods in cell biology ; 61, (1999)
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Severin, Fedor F.; Kaplan, Ken; Sorger, Peter; Hyman, Anthony A.
In vitro assays for studying Saccharomyces cerevisiae kinetochore activity
Mitosis and meiosis, chapt. 8, pp. 145-153, in: Methods in cell biology ; 61, (1999)
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