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Teymuras Kurzchalia

Publications

2011
Erkut, Cihan; Penkov, Sider; Khesbak, Hassan; Vorkel, Daniela; Verbavatz, Jean-Marc; Fahmy, Karim; Kurzchalia, Teymuras V.
Trehalose renders the dauer larva of Caenorhabditis elegans resistant to extreme desiccation.
Curr. Biol., 21, no. 15, pp. 1331-1336, (2011)
Penkov, Sider
Trehalose and trehalose lipids in Caenorhabditis elegans dauer larva
[Doctoral Thesis] Technische Universität Dresden, (2011)
2010
Penkov, Sider; Mende, Fanny; Zagoriy, Vyacheslav; Erkut, Cihan; Martin, René; Pässler, Ulrike; Schuhmann, Kai; Schwudke, Dominik; Gruner, Margit; Mäntler, Jana; Müller-Reichert, Thomas; Shevchenko, Andrej; Knölker, Hans-Joachim; Kurzchalia, Teymuras V.
Maradolipids: Diacyltrehalose Glycolipids Specific to Dauer Larva in Caenorhabditis elegans.
Angew. Chem. Int. Ed. Engl., 49, no. 49, pp. 9430-9435, (2010)
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Carvalho, Maria; Schwudke, Dominik; Sampaio, Julio; Palm, Wilhelm; Riezman, Isabelle; Dey, Gautam; Gupta, Gagan D; Mayor, Satyajit; Riezman, Howard; Shevchenko, Andrej; Kurzchalia, Teymuras V.; Eaton, Suzanne
Survival strategies of a sterol auxotroph.
Development, 137, no. 21, pp. 3675-3685, (2010)
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Zagoriy, Vyacheslav; Matyash, Vitali; Kurzchalia, Teymuras V.
Long-chain O-ascarosyl-alkanediols are constitutive components of Caenorhabditis elegans but do not induce dauer larva formation.
Chem. Biodivers., 7, no. 8, pp. 2016-2022, (2010)
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Aguilar, Pablo S; Heiman, Maxwell G; Walther, Tobias C; Engel, Alex; Schwudke, Dominik; Gushwa, Nathan; Kurzchalia, Teymuras V.; Walter, Peter
Structure of sterol aliphatic chains affects yeast cell shape and cell fusion during mating.
Proc. Natl. Acad. Sci. U.S.A., 107, no. 9, pp. 4170-4175, (2010)
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Martin, René; Entchev, Eugeni V.; Kurzchalia, Teymuras V.; Knölker, Hans-Joachim
Steroid hormones controlling the life cycle of the nematode Caenorhabditis elegans: stereoselective synthesis and biology.
Org. Biomol. Chem., 8, no. 4, pp. 739-750, (2010)
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2009
Zagoriy, Vyacheslav
Long chain O-ascarosyl alkanediols (ascarosides) of Caenorhabditis elegans
[Doctoral Thesis] Technische Universität Dresden, (2009)
Martin, René; Schäfer, Tina; Theumer, Gabriele; Entchev, Eugeni V.; Kurzchalia, Teymuras V.; Knölker, Hans-Joachim
Improved Synthesis of an Ascaroside Pheromone Controlling Dauer Larva Development in Caenorhabditis elegans
Synthesis, 41, no. 20, pp. 3488-3492, (2009)
Martin, René; Entchev, Eugeni V.; Däbritz, Frank; Kurzchalia, Teymuras V.; Knölker, Hans-Joachim
Synthesis and Hormonal Activity of the (25S)-Cholesten-26-oic Acids – Potent Ligands for the DAF-12 Receptor in Caenorhabditis elegans
Eur. J. Org. Chem., no. 22, pp. 3703-3714, (2009)
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Hannich, J Thomas; Entchev, Eugeni V.; Mende, Fanny; Boytchev, Hristio; Martin, René; Zagoriy, Vyacheslav; Theumer, Gabriele; Riezman, Isabelle; Riezman, Howard; Knölker, Hans-Joachim; Kurzchalia, Teymuras V.
Methylation of the sterol nucleus by STRM-1 regulates dauer larva formation in Caenorhabditis elegans.
Dev. Cell, 16, no. 6, pp. 833-843, (2009)
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Martin, René; Saini, Ratni; Bauer, Ingmar; Gruner, Margit; Kataeva, Olga; Zagoriy, Vyacheslav; Entchev, Eugeni V.; Kurzchalia, Teymuras V.; Knölker, Hans-Joachim
4Alpha-bromo-5alpha-cholestan-3beta-ol and nor-5alpha-cholestan-3beta-ol derivatives-stereoselective synthesis and hormonal activity in Caenorhabditis elegans.
Org. Biomol. Chem., 7, no. 11, pp. 2303-2309, (2009)
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Martin, René; Schmidt, Arndt W; Theumer, Gabriele; Krause, Tilo; Entchev, Eugeni V.; Kurzchalia, Teymuras V.; Knölker, Hans-Joachim
Synthesis and biological activity of the (25R)-cholesten-26-oic acids--ligands for the hormonal receptor DAF-12 in Caenorhabditis elegans.
Org. Biomol. Chem., 7, no. 5, pp. 909-920, (2009)
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Benenati, Gaspare; Penkov, Sider; Müller-Reichert, Thomas; Entchev, Eugeni V.; Kurzchalia, Teymuras V.
Two cytochrome P450s in Caenorhabditis elegans are essential for the organization of eggshell, correct execution of meiosis and the polarization of embryo.
Mech. Dev., 126, no. 5-6, pp. 382-393, (2009)
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Hannich, J Thomas
Lipid methylation in the development of Caenorhabditits elegans
[Doctoral Thesis] Technische Universität Dresden, (2009)
2008
Martin, René; Däbritz, Frank; Entchev, Eugeni V.; Kurzchalia, Teymuras V.; Knölker, Hans-Joachim
Stereoselective synthesis of the hormonally active (25S)-delta7-dafachronic acid, (25S)-Delta4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid.
Org. Biomol. Chem., 6, no. 23, pp. 4293-4295, (2008)
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Entchev, Eugeni V.; Schwudke, Dominik; Zagoriy, Vyacheslav; Matyash, Vitali; Bogdanova, Aliona; Habermann, Bianca; Zhu, Lin; Shevchenko, Andrej; Kurzchalia, Teymuras V.
LET-767 is required for the production of branched chain and long chain fatty acids in Caenorhabditis elegans.
J. Biol. Chem., 283, no. 25, pp. 17550-17560, (2008)
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Heimerl, Susanne; Liebisch, Gerhard; Lay, Soazig Le; Böttcher, Alfred; Wiesner, Philipp; Lindtner, Silke; Kurzchalia, Teymuras V.; Simons, Kai; Schmitz, Gerd
Caveolin-1 deficiency alters plasma lipid and lipoprotein profiles in mice.
Biochem. Biophys. Res. Commun., 367, no. 4, pp. 826-833, (2008)
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Lebreton, Magalie
New outlooks on the transport of cholesterol in Caenorhabditis elegans
[Doctoral Thesis] Technische Universität Dresden, (2008)
2006
Fernández, Manuel A; Albor, Cecilia; Ingelmo-Torres, Mercedes; Nixon, Susan J.; Ferguson, Charles; Kurzchalia, Teymuras V.; Tebar, Francesc; Enrich, Carlos; Parton, Robert G.; Pol, Albert
Caveolin-1 is essential for liver regeneration.
Science, 313, no. 5793, pp. 1628-1632, (2006)
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Waschke, Jens; Golenhofen, Nikola; Kurzchalia, Teymuras V.; Drenckhahn, Detlev
Protein kinase C-mediated endothelial barrier regulation is caveolin-1-dependent.
Histochem. Cell Biol., 126, no. 1, pp. 17-26, (2006)
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Yu, Jun; Bergaya, Sonia; Murata, Takahisa; Alp, Ilkay F.; Bauer, Michael P.; Lin, Michelle I; Drab, Marek; Kurzchalia, Teymuras V.; Stan, Radu V; Sessa, William C
Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels.
J. Clin. Invest., 116, no. 5, pp. 1284-1291, (2006)
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Schmidt, Arndt W; Doert, Thomas; Goutal, Sigrid; Gruner, Margit; Mende, Fanny; Kurzchalia, Teymuras V.; Knölker, Hans-Joachim
Regio- and Stereospecific Synthesis of Cholesterol Derivatives and their Hormonal Activity in Caenorhabditis elegans
Eur. J. Org. Chem., 16, pp. 3687-3706, (2006)
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2005
Lay, Soazig Le; Kurzchalia, Teymuras V.
Getting rid of caveolins: phenotypes of caveolin-deficient animals.
Biochim. Biophys. Acta, 1746, no. 3, pp. 322-333, (2005)
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Papanikolaou, Agathi; Papafotika, Alexandra; Murphy, Carol; Papamarcaki, Thomais; Tsolas, Orestes; Drab, Marek; Kurzchalia, Teymuras V.; Kasper, Michael; Christoforidis, Savvas
Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39.
J. Biol. Chem., 280, no. 28, pp. 26406-26414, (2005)
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Entchev, Eugeni V.; Kurzchalia, Teymuras V.
Requirement of sterols in the life cycle of the nematode Caenorhabditis elegans.
Semin. Cell Dev. Biol., 16, no. 2, pp. 175-182, (2005)
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Bacia, Kirsten; Schwille, Petra; Kurzchalia, Teymuras V.
Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes.
Proc. Natl. Acad. Sci. U.S.A., 102, no. 9, pp. 3272-3277, (2005)
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Kirkham, Matthew; Fujita, Akikazu; Chadda, Rahul; Nixon, Susan J.; Kurzchalia, Teymuras V.; Sharma, Deepak K; Pagano, Richard E; Hancock, John F.; Mayor, Satyajit; Parton, Robert G.
Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles.
J. Cell Biol., 168, no. 3, pp. 465-476, (2005)
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Damm, Eva-Maria; Pelkmans, Lucas; Kartenbeck, Jürgen; Mezzacasa, Anna; Kurzchalia, Teymuras V.; Helenius, Ari
Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae.
J. Cell Biol., 168, no. 3, pp. 477-488, (2005)
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2004
Matyash, Vitali; Entchev, Eugeni V.; Mende, Fanny; Wilsch-Bräuninger, Michaela; Thiele, Christoph; Schmidt, Arndt W; Knölker, Hans-Joachim; Ward, Samuel; Kurzchalia, Teymuras V.
Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16.
PLoS Biol., 2, no. 10, pp. 280-280, (2004)
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2003
Kurzchalia, Teymuras V.; Ward, Samuel
Why do worms need cholesterol?
Nat. Cell Biol., 5, no. 8, pp. 684-688, (2003)
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Lucius, H; Friedrichson, Tim; Kurzchalia, Teymuras V.; Lewin, G R
Identification of caveolae-like structures on the surface of intact cells using scanning force microscopy.
J. Membr. Biol., 194, no. 2, pp. 97-108, (2003)
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Kurzchalia, Teymuras V.
Anthrax toxin rafts into cells.
J. Cell Biol., 160, no. 3, pp. 295-296, (2003)
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Wyse, Bruce D.; Prior, Ian A.; Qian, Hongwei; Morrow, Isabel C.; Nixon, Susan J.; Muncke, Cornelia; Kurzchalia, Teymuras V.; Thomas, Walter G.; Parton, Robert G.; Hancock, John F.
Caveolin Interacts with the Angiotensin II Type 1 Receptor during Exocytic Transport but Not at the Plasma Membrane
J. Biol. Chem., 278, no. 26, pp. 23738-23746, (2003)
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2001
Drab, Marek; Verkade, Paul; Elger, Marlies; Kasper, Michael; Lohn, Matthias; Lauterbach, Birgit; Menne, Jan; Lindschau, Carsten; Mende, Fanny; Luft, Friedrich C.; Schedl, Aandreas; Haller, Hermann; Kurzchalia, Teymuras V.
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice.
Science, 293, no. 5539, pp. 2449-2452, (2001)
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Matyash, Vitali; Geier, Christian; Henske, Annemarie; Mukherjee, Sushmita; Hirsh, David; Thiele, Christoph; Grant, Barth; Maxfield, Frederick R.; Kurzchalia, Teymuras V.
Distribution and transport of cholesterol in Caenorhabditis elegans.
Mol. Biol. Cell, 12, no. 6, pp. 1725-1736, (2001)
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1999
Simons, Mikael; Friedrichson, Tim; Schulz, Jörg B; Pitto, Marina; Masserini, Massimo; Kurzchalia, Teymuras V.
Exogenous administration of gangliosides displaces GPI-anchored proteins from lipid microdomains in living cells.
Mol. Biol. Cell, 10, no. 10, pp. 3187-3196, (1999)
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Kurzchalia, Teymuras V.; Parton, Robert G.
Membrane microdomains and caveolae.
Curr. Opin. Cell Biol., 11, no. 4, pp. 424-431, (1999)
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Scheel, Jochen; Srinivasan, Jagan; Honnert, Ulrike; Henske, Annemarie; Kurzchalia, Teymuras V.
Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans.
Nat. Cell Biol., 1, no. 2, pp. 127-129, (1999)
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