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Marino Zerial

Publications

2014
Gerstner, Norman
Endocytic Modulation of Developmental Signaling during Zebrafish Gastrulation
[Doctoral Thesis] Technische Universität Dresden, (2014)
Simeone, Angela; Marsico, Giovanni; Collinet, Claudio; Galvez, Thierry; Kalaidzidis, Yannis; Zerial, Marino; Beyer, Andreas
Revealing molecular mechanisms by integrating high-dimensional functional screens with protein interaction data.
PLoS Comput. Biol., 10, no. 9, pp. 1003801-1003801, (2014)
Perini, Enrico; Schaefer, Ramona; Stöter, Martin; Kalaidzidis, Yannis; Zerial, Marino
Mammalian CORVET Is Required for Fusion and Conversion of Distinct Early Endosome Subpopulations.
Traffic, 15, no. 12, pp. 1366-1389, (2014)
Esner, Milan; Meyenhofer, Felix; Kuhn, Michael; Thomas, Melissa; Kalaidzidis, Yannis; Bickle, Marc
Development of a Kinetic Assay for Late Endosome Movement.
J. Biomol. Screen., pp. 1070-1078, (2014)
Sundaramurthy, Varadharajan; Barsacchi, Rico; Chernykh, Mikhail; Stöter, Martin; Tomschke, Nadine; Bickle, Marc; Kalaidzidis, Yannis; Zerial, Marino
Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen.
Nat. Protoc., 9, no. 2, pp. 474-490, (2014)
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Bogorad, Roman L; Yin, Hao; Zeigerer, Anja; Nonaka, Hidenori; Ruda, Vera M; Zerial, Marino; Anderson, Daniel G; Koteliansky, Victor
Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice.
Nat. Commun., 5, (2014)
2013
Ivanova, Anna; Kalaidzidis, Yannis; Dirkx, Ronald; Sarov, Mihail; Gerlach, Michael; Schroth-Diez, Britta; Müller, Andreas; Liu, Yanmei; Andree, Cordula; Mulligan, Bernard; Münster, Carla; Kurth, Thomas; Bickle, Marc; Speier, Stephan; Anastassiadis, Konstantinos; Solimena, Michele
Age-dependent labeling and imaging of insulin secretory granules.
Diabetes, 62, no. 11, pp. 3687-3696, (2013)
Gilleron, Jerome; Querbes, William; Zeigerer, Anja; Borodovsky, Anna; Marsico, Giovanni; Schubert, Undine; Manygoats, Kevin; Seifert, Sarah; Andree, Cordula; Stöter, Martin; Epstein-Barash, Hila; Zhang, Ligang; Koteliansky, Victor; Fitzgerald, Kevin; Fava, Eugenio; Bickle, Marc; Kalaidzidis, Yannis; Akinc, Akin; Maier, Martin A; Zerial, Marino
Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape.
Nat. Biotechnol., 31, no. 7, pp. 638-646, (2013)
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Kyrkou, A; Soufi, M; Bahtz, R; Ferguson, Charles; Bai, M; Parton, Robert G.; Hoffmann, Ingrid; Zerial, Marino; Fotsis, Theodore; Murphy, Carol
The RhoD to centrosomal duplication.
Small GTPases, 4, no. 2, pp. 116-122, (2013)
Kyrkou, A; Soufi, M; Bahtz, R; Ferguson, Charles; Bai, M; Parton, Robert G.; Hoffmann, I; Zerial, Marino; Fotsis, Theodore; Murphy, C
RhoD participates in the regulation of cell-cycle progression and centrosome duplication.
Oncogene, 32, no. 14, pp. 1831-1842, (2013)
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Perini, Enrico
In vitro reconstitution of the molecular mechanisms of vesicle tethering and membrane fusion
[Doctoral Thesis] Technische Universität Dresden, (2013)
Sundaramurthy, Varadharajan; Barsacchi, Rico; Samusik, Nikolay; Marsico, Giovanni; Gilleron, Jerome; Kalaidzidis, Inna; Meyenhofer, Felix; Bickle, Marc; Kalaidzidis, Yannis; Zerial, Marino
Integration of chemical and RNAi multiparametric profiles identifies triggers of intracellular mycobacterial killing.
Cell Host Microbe, 13, no. 2, pp. 129-142, (2013)
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2012
Gilleron, Jerome; Zeigerer, Anja; Marsico, Giovanni; Galvez, Thierry; Zerial, Marino
[Key role of Rab5: from endosome biogenesis to liver metabolism].
Med. Sci. (Paris), 28, no. 12, pp. 1041-1044, (2012)
Galvez, Thierry; Gilleron, Jerome; Zerial, Marino; O'Sullivan, Gregory A
SnapShot: Mammalian Rab proteins in endocytic trafficking.
Cell, 151, no. 1, (2012)
Foret, Lionel; Dawson, Jonathan E; Villaseñor, Roberto; Collinet, Claudio; Deutsch, Andreas; Brusch, Lutz; Zerial, Marino; Kalaidzidis, Yannis; Jülicher, Frank
A General Theoretical Framework to Infer Endosomal Network Dynamics from Quantitative Image Analysis.
Curr. Biol., 22, no. 15, pp. 1381-1390, (2012)
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Thompson, David B; Villaseñor, Roberto; Dorr, Brent M; Zerial, Marino; Liu, David R
Cellular uptake mechanisms and endosomal trafficking of supercharged proteins.
Chem. Biol., 19, no. 7, pp. 831-843, (2012)
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Fietz, Simone; Lachmann, Robert; Brandl, Holger; Kircher, Martin; Samusik, Nikolay; Schröder, Roland; Lakshmanaperumal, Naharajan; Henry, Ian; Vogt, Johannes; Riehn, Axel; Distler, Wolfgang; Nitsch, Robert; Enard, Wolfgang; Pääbo, Svante; Huttner, Wieland B.
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal.
Proc. Natl. Acad. Sci. U.S.A., 109, no. 29, pp. 11836-11841, (2012)
Schmees, C; Villaseñor, Roberto; Zheng, W; Ma, H; Zerial, Marino; Heldin, Carl-Henrik; Hellberg, C
Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V.
Mol. Biol. Cell, 23, no. 13, pp. 2571-2582, (2012)
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Winter, Julia Franziska; Höpfner, Sebastian; Korn, Kerstin; Farnung, Benjamin; Bradshaw, Charles R.; Marsico, Giovanni; Volkmer, Michael; Habermann, Bianca; Zerial, Marino
Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity.
Nat. Cell Biol., 14, no. 7, pp. 666-676, (2012)
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Barsacchi, Rico; Sundaramurthy, Varadharajan; Korbee, Kees; Neefjes, Jacques; Ottenhoff, Tom H. M.; Scanu, Tiziana; Zerial, Marino
Manipulating the Fight Between Human Host Cells and Intracellular Pathogens
Systems Microbiology: Current Topics and Applications, chapt. 5, pp. 77-94, (2012)
Zeigerer, Anja; Gilleron, Jerome; Bogorad, Roman L; Marsico, Giovanni; Nonaka, Hidenori; Seifert, Sarah; Epstein-Barash, Hila; Kuchimanchi, Satya; Peng, Chang Geng; Ruda, Vera M; Conte-Zerial, Perla Del; Hengstler, Jan G; Kalaidzidis, Yannis; Koteliansky, Victor; Zerial, Marino
Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.
Nature, 485, no. 7399, pp. 465-470, (2012)
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Stein, Matthias; Pilli, Manohar; Bernauer, Sabine; Habermann, Bianca; Zerial, Marino; Wade, Rebecca C
The interaction properties of the human Rab GTPase family--comparative analysis reveals determinants of molecular binding selectivity.
PLoS ONE, 7, no. 4, (2012)
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Pan-Montojo, Francisco; Schwarz, Mathias; Winkler, Christian; Arnhold, Mike; O'Sullivan, Gregory A; Pal, Arun; Said, Jonas; Marsico, Giovanni; Verbavatz, Jean-Marc; Rodrigo-Angulo, Margarita; Gille, Gabriele; Funk, Richard; Reichmann, Heinz
Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice.
Sci. Rep., 2, (2012)
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2011
Poznyakovskiy, Anton A; Zahnert, Thomas; Kalaidzidis, Yannis; Lazurashvili, Nikoloz; Schmidt, Rolf; Hardtke, Hans-Jürgen; Fischer, Björn; Yarin, Yury M
A segmentation method to obtain a complete geometry model of the hearing organ.
Hear. Res., 282, no. 1-2, pp. 25-34, (2011)
Akhtar, Asifa; Fuchs, Elaine; Mitchison, Timothy J.; Shaw, Reuben J; Johnston, Daniel St; Strasser, Andreas; Taylor, Susan; Walczak, Claire E.; Zerial, Marino
A decade of molecular cell biology: achievements and challenges.
Nat. Rev. Mol. Cell Biol., 12, no. 10, pp. 669-674, (2011)
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Urbanska, Anna; Sadowski, Lukasz; Kalaidzidis, Yannis; Miaczynska, Marta
Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment
Traffic, 12, no. 9, pp. 1227-1241, (2011)
Pilecka, Iwona; Sadowski, Lukasz; Kalaidzidis, Yannis; Miaczynska, Marta
Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment
Exp. Cell Res., 317, no. 8, pp. 1093-1107, (2011)
Marsico, Giovanni
Analysis of the interplay between endocytosis and cell morphology through the development of computational methods
[Doctoral Thesis] Technische Universität Dresden, (2011)
Tang, Danming; Xiang, Yi; Renzis, Stefano de; Rink, Jochen; Zheng, Gen; Zerial, Marino; Wang, Yanzhuang
The ubiquitin ligase HACE1 regulates Golgi membrane dynamics during the cell cycle.
Nat. Commun., 2, (2011)
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2010
Chandrashaker, Akhila
Systems analysis of early endosome motility through identification of molecular motors
[Doctoral Thesis] Technische Universität Dresden, (2010)
Akinc, Akin; Querbes, William; De, Soma; Qin, June; Frank-Kamenetsky, Maria; Jayaprakash, K Narayanannair; Jayaraman, Muthusamy; Rajeev, Kallanthottathil G; Cantley, William L; Dorkin, J Robert; Butler, James S; Qin, Liuliang; Racie, Timothy; Sprague, Andrew; Fava, Eugenio; Zeigerer, Anja; Hope, Michael J; Zerial, Marino; Sah, Dinah W Y; Fitzgerald, Kevin; Tracy, Mark A; Manoharan, Muthiah; Koteliansky, Victor; Fougerolles, Antonin de; Maier, Martin A
Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.
Mol. Ther., 18, no. 7, pp. 1357-1364, (2010)
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Mottola, Giovanna; Classen, Anne-Kathrin; González-Gaitán, Marcos; Eaton, Suzanne; Zerial, Marino
A novel function for the Rab5 effector Rabenosyn-5 in planar cell polarity.
Development, 137, no. 14, pp. 2353-2364, (2010)
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Farhan, Hesso; Wendeler, Markus W; Mitrovic, Sandra; Fava, Eugenio; Silberberg, Yael; Sharan, Roded; Zerial, Marino; Hauri, Hans-Peter
MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening.
J. Cell Biol., 189, no. 6, pp. 997-1011, (2010)
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Poteryaev, Dmitry; Datta, Sunando; Ackema, Karin; Zerial, Marino; Spang, Anne
Identification of the switch in early-to-late endosome transition.
Cell, 141, no. 3, pp. 497-508, (2010)
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Collinet, Claudio; Stöter, Martin; Bradshaw, Charles R.; Samusik, Nikolay; Rink, Jochen; Kenski, Denise; Habermann, Bianca; Buchholz, Frank; Henschel, Robert; Mueller, Matthias S; Nagel, Wolfgang E; Fava, Eugenio; Kalaidzidis, Yannis; Zerial, Marino
Systems survey of endocytosis by multiparametric image analysis.
Nature, 464, no. 7286, pp. 243-249, (2010)
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Goto-Silva, Livia
Characterization of APPL signalling endosomes in neurons
[Doctoral Thesis] Technische Universität Dresden, (2010)
2009
Helbing, Dirk; Deutsch, Andreas; Diez, Stefan; Peters, Karsten; Kalaidzidis, Yannis; Padberg-Gehle, Kathrin; Lämmer, Stefan; Johansson, Anders; Breier, Georg; Schulze, Frank; Zerial, Marino
Biologistics and the struggle for efficiency: concepts and perspectives
Adv. complex systems, 12, no. 6, pp. 533-548, (2009)
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Ohya, Takeshi; Miaczynska, Marta; Coskun, Uenal; Lommer, Barbara; Runge, Anja; Drechsel, David N.; Kalaidzidis, Yannis; Zerial, Marino
Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.
Nature, 459, no. 7250, pp. 1091-1097, (2009)
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Bramsen, Jesper B; Laursen, Maria B; Nielsen, Anne F; Hansen, Thomas B; Bus, Claus; Langkjaer, Niels; Babu, B Ravindra; Højland, Torben; Abramov, Mikhail; Aerschot, Arthur Van; Odadzic, Dalibor; Smicius, Romualdas; Haas, Jens; Andree, Cordula; Barman, Jharna; Wenska, Malgorzata; Srivastava, Puneet; Zhou, Chuanzheng; Honcharenko, Dmytro; Hess, Simone; Müller, Elke; Bobkov, Georgii V; Mikhailov, Sergey N; Fava, Eugenio; Meyer, Thomas F; Chattopadhyaya, Jyoti; Zerial, Marino; Engels, Joachim W; Herdewijn, Piet; Wengel, Jesper; Kjems, Jørgen
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity.
Nucleic Acids Res., 37, no. 9, pp. 2867-2881, (2009)
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Collinet, Claudio
System survey of endocytosis by functional genomics and quantitative multi-parametric image analysis
[Doctoral Thesis] Technische Universität Dresden, (2009)
Deribe, Yonathan Lissanu; Wild, Philipp; Chandrashaker, Akhila; Curak, Jasna; Schmidt, Mario; Kalaidzidis, Yannis; Milutinovic, Natasa; Kratchmarova, Irina; Buerkle, Lukas; Fetchko, Michael J; Schmidt, Philipp; Kittanakom, Saranya; Brown, Kevin R; Jurisica, Igor; Blagoev, Blagoy; Zerial, Marino; Stagljar, Igor; Dikic, Ivan
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.
Sci. Signal., 2, no. 102, (2009)
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Kalaidzidis, Yannis
Multiple objects tracking in fluorescence microscopy.
J. Math. Biol., 58, no. 1-2, pp. 57-80, (2009)
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Bradshaw, Charles R.
Improving the analysis of genome-wide screens through the detection of weakly conserved domains
[Doctoral Thesis] Technische Universität Dresden, (2009)
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2008
Poznyakovskiy, Anton A; Zahnert, Thomas; Kalaidzidis, Yannis; Schmidt, Rolf; Fischer, Björn; Baumgart, Johannes; Yarin, Yury M
The creation of geometric three-dimensional models of the inner ear based on micro computer tomography data.
Hear. Res., 243, no. 1-2, pp. 95-104, (2008)
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McShane, Marisa P.; Zerial, Marino
Survival of the weakest: signaling aided by endosomes.
J. Cell Biol., 182, no. 5, pp. 823-825, (2008)
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Schenck, Annette; Goto-Silva, Livia; Collinet, Claudio; Rhinn, Muriel; Giner, Angelika; Habermann, Bianca; Brand, Michael; Zerial, Marino
The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development.
Cell, 133, no. 3, pp. 486-497, (2008)
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Pal, Arun; Severin, Fedor F.; Höpfner, Sebastian; Zerial, Marino
Regulation of endosome dynamics by Rab5 and Huntingtin-HAP40 effector complex in physiological versus pathological conditions
Small GTPases in disease, chapt. 17, pp. 239-257, in: Methods in enzymology ; 438, (2008)
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Conte-Zerial, Perla Del; Brusch, Lutz; Rink, Jochen; Collinet, Claudio; Kalaidzidis, Yannis; Zerial, Marino; Deutsch, Andreas
Membrane identity and GTPase cascades regulated by toggle and cut-out switches.
Mol. Syst. Biol., 4, pp. 206-206, (2008)
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Winter, Julia Franziska
Genome-wide analysis of membrane trafficking in polarised epithelial cells in the C. elegans intestine
[Doctoral Thesis] Technische Universität Dresden, (2008)
2007
Kalaidzidis, Yannis
Intracellular objects tracking.
Eur. J. Cell Biol., 86, no. 9, pp. 569-578, (2007)
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Lessmann, Torben; Leuenberger, Michele G; Menninger, Sascha; Lopez-Canet, Meritxell; Müller, Oliver; Hümmer, Stefan; Bormann, Jenny; Korn, Kerstin; Fava, Eugenio; Zerial, Marino; Mayer, Thomas U; Waldmann, Herbert
Natural product-derived modulators of cell cycle progression and viral entry by enantioselective oxa Diels-Alder reactions on the solid phase.
Chem. Biol., 14, no. 4, pp. 443-451, (2007)
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Kicheva, Anna; Pantazis, Periklis; Bollenbach, Tobias; Kalaidzidis, Yannis; Bittig, Thomas; Jülicher, Frank; González-Gaitán, Marcos
Kinetics of morphogen gradient formation.
Science, 315, no. 5811, pp. 521-525, (2007)
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2006
Pal, Arun; Severin, Fedor F.; Lommer, Barbara; Shevchenko, Anna; Zerial, Marino
Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease.
J. Cell Biol., 172, no. 4, pp. 605-618, (2006)
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2005
Martin, Sally; Driessen, Kim; Nixon, Susan J.; Zerial, Marino; Parton, Robert G.
Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism.
J. Biol. Chem., 280, no. 51, pp. 42325-42335, (2005)
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Rink, Jochen; Ghigo, Eric; Kalaidzidis, Yannis; Zerial, Marino
Rab conversion as a mechanism of progression from early to late endosomes.
Cell, 122, no. 5, pp. 735-749, (2005)
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Macé, Gaëtane; Miaczynska, Marta; Zerial, Marino; Nebreda, Angel R
Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis.
EMBO J., 24, no. 18, pp. 3235-3246, (2005)
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Shin, Hye-Won; Hayashi, Mitsuko; Christoforidis, Savvas; Lacas-Gervais, Sandra; Hoepfner, Sebastian; Wenk, Markus R; Modregger, Jan; Uttenweiler-Joseph, Sandrine; Wilm, Matthias; Nystuen, Arne; Frankel, Wayne N; Solimena, Michele; Camilli, Pietro De; Zerial, Marino
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway.
J. Cell Biol., 170, no. 4, pp. 607-618, (2005)
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Pelkmans, Lucas; Zerial, Marino
Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae.
Nature, 436, no. 7047, pp. 128-133, (2005)
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Pelkmans, Lucas; Fava, Eugenio; Grabner, Hannes; Hannus, Michael; Habermann, Bianca; Krausz, Eberhard; Zerial, Marino
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis.
Nature, 436, no. 7047, pp. 78-86, (2005)
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Höpfner, Sebastian
Modulation of Cargo Transport and Sorting through Endosome Motility and Positioning
[Doctoral Thesis] Technische Universität Dresden, (2005)
Hoepfner, Sebastian; Severin, Fedor F.; Cabezas, Alicia; Habermann, Bianca; Runge, Anja; Gillooly, David J.; Stenmark, Harald; Zerial, Marino
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B.
Cell, 121, no. 3, pp. 437-450, (2005)
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Krausz, Eberhard; Pelkmans, Lucas; Fava, Eugenio; Hannus, Michael; Möbius, Claudia; Korn, Kerstin; Halley, Francoise; Lohmann, Annett; Grabner, Hannes; Zerial, Marino
Genomweite funktionelle Analyse des Kinoms mittels RNA-Interfernz
BIOspektrum, 11, no. SH, pp. 518-520, (2005)
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2004
Schnatwinkel, Carsten; Christoforidis, Savvas; Lindsay, Margaret R; Uttenweiler-Joseph, Sandrine; Wilm, Matthias; Parton, Robert G.; Zerial, Marino
The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms.
PLoS Biol., 2, no. 9, pp. 261-261, (2004)
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Pelkmans, Lucas; Bürli, Thomas; Zerial, Marino; Helenius, Ari
Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic.
Cell, 118, no. 6, pp. 767-780, (2004)
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Miaczynska, Marta; Pelkmans, Lucas; Zerial, Marino
Not just a sink: endosomes in control of signal transduction.
Curr. Opin. Cell Biol., 16, no. 4, pp. 400-406, (2004)
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Miaczynska, Marta; Christoforidis, Savvas; Giner, Angelika; Shevchenko, Anna; Uttenweiler-Joseph, Sandrine; Habermann, Bianca; Wilm, Matthias; Parton, Robert G.; Zerial, Marino
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment.
Cell, 116, no. 3, pp. 445-456, (2004)
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2003
Gasman, Stéphane; Kalaidzidis, Yannis; Zerial, Marino
RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase.
Nat. Cell Biol., 5, no. 3, pp. 195-204, (2003)
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Mattera, Rafael; Arighi, Cecilia N; Lodge, Robert; Zerial, Marino; Bonifacino, Juan S
Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex.
EMBO J., 22, no. 1, pp. 78-88, (2003)
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2002
Murray, James T; Panaretou, Christina; Stenmark, Harald; Miaczynska, Marta; Backer, Jonathan M
Role of Rab5 in the recruitment of hVps34/p150 to the early endosome.
Traffic, 3, no. 6, pp. 416-427, (2002)
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Panopoulou, Ekaterini; Gillooly, David J.; Wrana, Jeffrey L; Zerial, Marino; Stenmark, Harald; Murphy, Carol; Fotsis, Theodore
Early endosomal regulation of Smad-dependent signaling in endothelial cells.
J. Biol. Chem., 277, no. 20, pp. 18046-18052, (2002)
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Renzis, Stefano de; Sönnichsen, Birte; Zerial, Marino
Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes.
Nat. Cell Biol., 4, no. 2, pp. 124-133, (2002)
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Miaczynska, Marta; Zerial, Marino
Mosaic organization of the endocytic pathway.
Exp. Cell Res., 272, no. 1, pp. 8-14, (2002)
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2001
Lippé, Roger; Miaczynska, Marta; Rybin, Vladimir; Runge, Anja; Zerial, Marino
Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex.
Mol. Biol. Cell, 12, no. 7, pp. 2219-2228, (2001)
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Esters, Heike; Alexandrov, Kirill; Iakovenko, Andrei; Ivanova, Tania; Thomä, Nicolas; Rybin, Vladimir; Zerial, Marino; Scheidig, Axel J.; Goody, Roger S.
Vps9, Rabex-5 and DSS4: proteins with weak but distinct nucleotide-exchange activities for Rab proteins.
J. Mol. Biol., 310, no. 1, pp. 141-156, (2001)
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Murphy, Carol; Saffrich, Rainer; Olivo-Marin, Jean-Christophe; Giner, Angelika; Ansorge, Wilhelm; Fotsis, Theodore; Zerial, Marino
Dual function of rhoD in vesicular movement and cell motility.
Eur. J. Cell Biol., 80, no. 6, pp. 391-398, (2001)
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Uttenweiler-Joseph, Sandrine; Neubauer, Gitte; Christoforidis, Savvas; Zerial, Marino; Wilm, Matthias
Automated de novo sequencing of proteins using the differential scanning technique.
Proteomics, 1, no. 5, pp. 668-682, (2001)
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Putte, Tom Van de; Zwijsen, An; Lonnoy, Olivier; Rybin, Vladimir; Cozijnsen, Miranda; Francis, Annick; Baekelandt, Veerle; Kozak, Christine A.; Zerial, Marino; Huylebroeck, Danny
Mice with a homozygous gene trap vector insertion in mgcRacGAP die during pre-implantation development.
Mech. Dev., 102, no. 1-2, pp. 33-44, (2001)
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Zerial, Marino; McBride, Heidi M.
Rab proteins as membrane organizers.
Nat. Rev. Mol. Cell Biol., 2, no. 2, pp. 107-117, (2001)
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Christoforidis, Savvas; Zerial, Marino
Purification of EEA1 from bovine brain cytosol using Rab5 affinity chromatography and activity assays
GTPases involved in vesicular traffic, chapt. 14, pp. 120-132, in: Methods in enzymology ; 329, (2001)
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Stenmark, Harald; Zerial, Marino
Molecular mechanisms of membrane fusion in the endocytic pathway
Endocytosis, chapt. 5, pp. 94-110, in: Frontiers in molecular biology ; 36, (2001)
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Nielsen, Erik; Severin, Fedor F.; Hyman, Anthony A.; Zerial, Marino
In vitro reconstitution of endosome motility along microtubules
Kinesin protocols, chapt. 12, pp. 133-146, in: Methods in molecular biology ; 164, (2001)
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Lippé, Roger; Horiuchi, Hisanori; Runge, Anja; Zerial, Marino
Expression, purification, and characterization of Rab5 effector complex, rabaptin-5/rabex-5
GTPases involved in vesicular traffic, pp. 132-145, in: Methods in enzymology ; 329, (2001)
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2000
Lanzetti, Letizia; Rybin, Vladimir; Malabarba, Maria Grazia; Christoforidis, Savvas; Scita, Giorgio; Zerial, Marino; Fiore, Pier Paolo Di
The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5.
Nature, 408, no. 6810, pp. 374-377, (2000)
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Nielsen, Erik; Christoforidis, Savvas; Uttenweiler-Joseph, Sandrine; Miaczynska, Marta; Dewitte, Frederique; Wilm, Matthias; Hoflack, Bernard; Zerial, Marino
Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain.
J. Cell Biol., 151, no. 3, pp. 601-612, (2000)
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Lehtonen, Sanna; Ora, Ari; Olkkonen, Vesa M; Geng, Lin; Zerial, Marino; Somlo, Stefan; Lehtonen, Eero
In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.
J. Biol. Chem., 275, no. 42, pp. 32888-32893, (2000)
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Sönnichsen, Birte; Renzis, Stefano de; Nielsen, Erik; Rietdorf, Jens; Zerial, Marino
Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11.
J. Cell Biol., 149, no. 4, pp. 901-914, (2000)
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Christoforidis, Savvas; Zerial, Marino
Purification and identification of novel Rab effectors using affinity chromatography.
Methods, 20, no. 4, pp. 403-410, (2000)
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Rubino, Mariantonietta; Miaczynska, Marta; Lippé, Roger; Zerial, Marino
Selective membrane recruitment of EEA1 suggests a role in directional transport of clathrin-coated vesicles to early endosomes.
J. Biol. Chem., 275, no. 6, pp. 3745-3748, (2000)
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1999
Christoforidis, Savvas; Miaczynska, Marta; Ashman, Keith; Wilm, Matthias; Zhao, Liyun; Yip, Shu-Chin; Waterfield, Michael D.; Backer, Jonathan M; Zerial, Marino
Phosphatidylinositol-3-OH kinases are Rab5 effectors.
Nat. Cell Biol., 1, no. 4, pp. 249-252, (1999)
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McBride, Heidi M.; Rybin, Vladimir; Murphy, Carol; Giner, Angelika; Teasdale, Rohan; Zerial, Marino
Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13.
Cell, 98, no. 3, pp. 377-386, (1999)
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Mulholland, Jon; Konopka, James; Singer-Kruger, Birgit; Zerial, Marino; Botstein, David
Visualization of receptor-mediated endocytosis in yeast.
Mol. Biol. Cell, 10, no. 3, pp. 799-817, (1999)
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Christoforidis, Savvas; McBride, Heidi M.; Burgoyne, Robert D.; Zerial, Marino
The Rab5 effector EEA1 is a core component of endosome docking.
Nature, 397, no. 6720, pp. 621-625, (1999)
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1998
Lehtonen, Sanna; Olkkonen, Vesa M; Stapleton, Mark; Zerial, Marino; Lehtonen, Eero
HMG-17, a chromosomal non-histone protein, shows developmental regulation during organogenesis.
Int. J. Dev. Biol., 42, no. 6, pp. 775-782, (1998)
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Simonsen, Anne; Lippé, Roger; Christoforidis, Savvas; Gaullier, Jean-Michel; Brech, Andreas; Callaghan, Judy; Toh, Ban-Hock; Murphy, Carol; Zerial, Marino; Stenmark, Harald
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion.
Nature, 394, no. 6692, pp. 494-498, (1998)
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Gournier, Helene; Stenmark, Harald; Rybin, Vladimir; Lippé, Roger; Zerial, Marino
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion.
EMBO J., 17, no. 7, pp. 1930-1940, (1998)
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Vitale, Gaetano; Rybin, Vladimir; Christoforidis, Savvas; Thornqvist, Per-Ove; McCaffrey, Mary; Stenmark, Harald; Zerial, Marino
Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5.
EMBO J., 17, no. 7, pp. 1941-1951, (1998)
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Zacchi, Paola; Stenmark, Harald; Parton, Robert G.; Orioli, Donata; Lim, Filip; Giner, Angelika; Mellman, Ira; Zerial, Marino; Murphy, Carol
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells.
J. Cell Biol., 140, no. 5, pp. 1039-1053, (1998)
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Stenmark, Harald; Zerial, Marino
Transient Expression Using the T7 RNA Polymerase Recombinant Vaccinia Virus System
Cell Biology: A Laboratory Handbook, 2nd Edition, Vol. 4, chapt. 14, pp. 201-203, (1998)
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Stenmark, Harald; Zerial, Marino
Stock Preparation of Recombinant Vaccinia Virus
Cell Biology: A Laboratory Handbook, 2nd Edition, Vol. 1, pp. 540-543, (1998)
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Zerial, Marino
Membranes and sorting
Curr. Opin. Cell Biol., 10, pp. 475-476, (1998)
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1997
Stenmark, Harald; Zerial, Marino
Lipofection
Cell Biology: A Laboratory Handbook, 2nd Edition, Vol. 4, chapt. 13, pp. 141-144, (1997)
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